An ICA-ensemble learning approaches for prediction of RNA-seq malaria vector gene expression data classification

Malaria parasites introduce outstanding life-phase variations as they grow across multiple atmospheres of the mosquito vector. There are transcriptomes of several thousand different parasites. (RNA-seq) Ribonucleic acid sequencing is a prevalent gene expression tool leading to better understanding of genetic interrogations. RNA-seq measures transcriptions of expressions of genes. Data from RNA-seq necessitate procedural enhancements in machine learning techniques. Researchers have suggested various approached learning for the study of biological data. This study works on ICA feature extraction algorithm to realize dormant components from a huge dimensional RNA-seq vector dataset, and estimates its classification performance, Ensemble classification algorithm is used in carrying out the experiment. This study is tested on RNA-Seq mosquito anopheles gambiae dataset. The results of the experiment obtained an output metrics with a 93.3% classification accuracy

Access to Dry Season Agricultural Content in the Broadcast Media and Dry Season Irrigation Farming among Smallholder Farmers in Nigeria

Inaccessibility to information could hinder the adoption of dry season agriculture which is very significant to ending the spate of food insecurity in Nigeria. This cross-sectional survey examined access to broadcast media agricultural content and the effect of such information on dry season agriculture practice among smallholder farmers in Nigeria’s Federal Capital Territory (FCT).Participants consisted of 381 smallholder farmers selected from rural settlements in Kuje and Kwali Area councils, through a multi-stage sampling procedure. Data for the study was generated via a self-designed questionnaire. The findings of this study show that access to the broadcast media agricultural content is high (94.2%) in the FCT and the majority (83.1%) of the farmers are particularly exposed to agricultural programmes on dry season farming. However, the regularity of exposure to such programmes is considered rare/occasional by a sizable proportion (44.8%) of the selected farmers. The research further confirms the general acceptability of the broadcast programmes on dry season agriculture but the major snag is that the majority (>50%) of the farmers think that the time at which the information is broadcast is inappropriate. In terms of the practical implications of the programmes, findings also revealed that 50%) remain adamant that dry-season farming is not achievable and productive; therefore, they have not engaged in dry season irrigation agriculture. We concluded that the knowledge gained from the dry season agricultural programmes in the broadcast media is not sufficient for farmers to successfully engage in dry season irrigation farming. The study recommends a long-term and sustained media campaign on dry season farming, the use of interactive programme content, and rescheduling agricultural programmes to farmers’ preferred time could yield the desired impact on dry season irrigation farming and food security in Nigeri

Access to Dry Season Agricultural Content in the Broadcast Media and Dry Season Irrigation Farming among Smallholder Farmers in Nigeria

Inaccessibility to information could hinder the adoption of dry season agriculture which is very significant to ending the spate of food insecurity in Nigeria. This cross-sectional survey examined access to broadcast media agricultural content and the effect of such information on dry season agriculture practice among smallholder farmers in Nigeria’s Federal Capital Territory (FCT). Participants consisted of 381 smallholder farmers selected from rural settlements in Kuje and Kwali Area councils, through a multi-stage sampling procedure. Data for the study was generated via a self-designed questionnaire. The findings of this study show that access to the broadcast media agricultural content is high (94.2%) in the FCT and the majority (83.1%) of the farmers are particularly exposed to agricultural programmes on dry season farming. However, the regularity of exposure to such programmes is considered rare/occasional by a sizable proportion (44.8%) of the selected farmers. The research further confirms the general acceptability of the broadcast programmes on dry season agriculture but the major snag is that the majority (>50%) of the farmers think that the time at which the information is broadcast is inappropriate. In terms of the practical implications of the programmes, findings also revealed that 50%) remain adamant that dry-season farming is not achievable and productive; therefore, they have not engaged in dry season irrigation agriculture. We concluded that the knowledge gained from the dry season agricultural programmes in the broadcast media is not sufficient for farmers to successfully engage in dry season irrigation farming. The study recommends a long-term and sustained media campaign on dry season farming, the use of interactive programme content, and rescheduling agricultural programmes to farmers’ preferred time could yield the desired impact on dry season irrigation farming and food security in Nigeria

Poultry Manure Addition Affects Production, Plant Nutritional Status and Heavy Metals Accumulation in Green Amaranth (Amaranthus hybridus)

Poultry manure (PM) application may be critical as source of contaminants and may affect crop quality. Experiments were conducted in 2016 and 2017 cropping seasons to determine effects of PM on performance and quality of green amaranth including some minerals and heavy metals in soil and plant tissues. In both years, PM were applied at 0, 10, 20, 30 and 40 t∙ha-1. Application of PM increased soil chemical properties, leaf mineral content, growth and marketable yield of green amaranth compared with the control. Soil pH, organic matter, N and P and leaf mineral N and P were increased up to 40 t ha-1 PM, but soil and leaf K, Ca, Mg, ash, protein, fiber contents were increased up to 20 t ha-1 PM. The lowest fat was observed at 20 t ha-1 PM. Dry matter declined as PM level increased. The PM influenced soil and leaf As, Cu and Zn, the abundance of heavy metals in soil and green amaranth leaf increased as level of PM increased. In soil and green amaranth leaves, levels of As, Cu and Zn as affected by PM did not exceed maximum permissible limits. The best green amaranth quality was obtained at 20 t ha-1 PM and may likely provides a good balance between yield and economic outlay. © 2019 Friends Science Publishers Keywords: Amaranthus hybridus; As; Cu; Leaf mineral content; Soil chemical properties; Z

Development and Process Optimization of a Ready-to-Eat Snack from Rice-Cowpea Composite by a Twin Extruder

A central composite rotatable design with four independent variables viz. blend ratio (broken rice flour and cowpea flour): 90:10–70:30, moisture content (10–18% wet basis), barrel temperature (110–150 ◦C), and screw speed (280–360 rpm) were varied in the development of ready-to-eat snacks using a twin extruder for a broken rice–cowpea product. The effects of the independent variables on specific mechanical energy, water absorption index, water solubility index, total color, hardness, bulk density, expansion ratio, and overall acceptability of the extruded snack were investigated using regression analysis. The results showed that the physical qualities of the ready-to-eat snacks were significantly affected by the extrusion parameters (i.e., blend ratio, barrel temperature, moisture content, and screw speed). From the findings, it was observed that screw speed and moisture contents affected hardness, while water absorption index was affected by all the extrusion parameters. However, the water solubility index and overall acceptance were majorly affected by the moisture content; extrudate produced with barrel ratio of 85:15, 12% moisture content, barrel temperature of 140 ◦C, and screw speed of 300 rpm was the most acceptable, at 6.73 on a 9 point hedonic scales. The blend ratio and barrel temperature influenced the expansion. Furthermore, the combination of cowpea and broken rice to produce nutritious ready-to-eat snacks has high acceptability and is a promising panacea for food security. Keywords: broken rice; cowpea; extrusion; food security and ready-to-eat snack

Assessment of the contribution of TEX air pollutants from Nigeria’s petroleum refineries to the ambient air quality: Part II

Environmental hazards associated with release of emission from petroleum refineries have caused serious concerns for the host communities. The study focused on the assessment of the contribution of Nigerian refineries to the ambient air quality. Total emission of toluene, ethyl benzene and xylene (TEX) from Nigerian twenty-six (four existing and twenty-two proposed) refineries were estimated using emission factor approach, under no-control measure (worst case scenario) option. Results showed that the four existing refineries emit 2.90 × 1013 tons of toluene, 1.93 × 1013 tons ethyl benzene and 1.06 × 1013 tons per year while the twenty-two proposed refineries have the capacity of releasing annually 9.17 × 1013 tons of toluene, 6.69 × 1013 tons of ethyl benzene and .95 x 1013 tons of xylene. If operated at full capacity, the total estimated TEX emission from the existing refineries stood at 5.89 × 1013 tons/year while the proposed refineries have the potential of adding additional 2.01 × 1014 tons/year. These concentrations were considered as environmental menace that could have adverse health challenge of the residents of the host communities. Some technologically driven measures to control and subsequently reduce TEX emission from these refineries were suggested

Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021

BACKGROUND Regular, detailed reporting on population health by underlying cause of death is fundamental for public health decision making. Cause-specific estimates of mortality and the subsequent effects on life expectancy worldwide are valuable metrics to gauge progress in reducing mortality rates. These estimates are particularly important following large-scale mortality spikes, such as the COVID-19 pandemic. When systematically analysed, mortality rates and life expectancy allow comparisons of the consequences of causes of death globally and over time, providing a nuanced understanding of the effect of these causes on global populations. METHODS The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 cause-of-death analysis estimated mortality and years of life lost (YLLs) from 288 causes of death by age-sex-location-year in 204 countries and territories and 811 subnational locations for each year from 1990 until 2021. The analysis used 56 604 data sources, including data from vital registration and verbal autopsy as well as surveys, censuses, surveillance systems, and cancer registries, among others. As with previous GBD rounds, cause-specific death rates for most causes were estimated using the Cause of Death Ensemble model-a modelling tool developed for GBD to assess the out-of-sample predictive validity of different statistical models and covariate permutations and combine those results to produce cause-specific mortality estimates-with alternative strategies adapted to model causes with insufficient data, substantial changes in reporting over the study period, or unusual epidemiology. YLLs were computed as the product of the number of deaths for each cause-age-sex-location-year and the standard life expectancy at each age. As part of the modelling process, uncertainty intervals (UIs) were generated using the 2·5th and 97·5th percentiles from a 1000-draw distribution for each metric. We decomposed life expectancy by cause of death, location, and year to show cause-specific effects on life expectancy from 1990 to 2021. We also used the coefficient of variation and the fraction of population affected by 90% of deaths to highlight concentrations of mortality. Findings are reported in counts and age-standardised rates. Methodological improvements for cause-of-death estimates in GBD 2021 include the expansion of under-5-years age group to include four new age groups, enhanced methods to account for stochastic variation of sparse data, and the inclusion of COVID-19 and other pandemic-related mortality-which includes excess mortality associated with the pandemic, excluding COVID-19, lower respiratory infections, measles, malaria, and pertussis. For this analysis, 199 new country-years of vital registration cause-of-death data, 5 country-years of surveillance data, 21 country-years of verbal autopsy data, and 94 country-years of other data types were added to those used in previous GBD rounds. FINDINGS The leading causes of age-standardised deaths globally were the same in 2019 as they were in 1990; in descending order, these were, ischaemic heart disease, stroke, chronic obstructive pulmonary disease, and lower respiratory infections. In 2021, however, COVID-19 replaced stroke as the second-leading age-standardised cause of death, with 94·0 deaths (95% UI 89·2-100·0) per 100 000 population. The COVID-19 pandemic shifted the rankings of the leading five causes, lowering stroke to the third-leading and chronic obstructive pulmonary disease to the fourth-leading position. In 2021, the highest age-standardised death rates from COVID-19 occurred in sub-Saharan Africa (271·0 deaths [250·1-290·7] per 100 000 population) and Latin America and the Caribbean (195·4 deaths [182·1-211·4] per 100 000 population). The lowest age-standardised death rates from COVID-19 were in the high-income super-region (48·1 deaths [47·4-48·8] per 100 000 population) and southeast Asia, east Asia, and Oceania (23·2 deaths [16·3-37·2] per 100 000 population). Globally, life expectancy steadily improved between 1990 and 2019 for 18 of the 22 investigated causes. Decomposition of global and regional life expectancy showed the positive effect that reductions in deaths from enteric infections, lower respiratory infections, stroke, and neonatal deaths, among others have contributed to improved survival over the study period. However, a net reduction of 1·6 years occurred in global life expectancy between 2019 and 2021, primarily due to increased death rates from COVID-19 and other pandemic-related mortality. Life expectancy was highly variable between super-regions over the study period, with southeast Asia, east Asia, and Oceania gaining 8·3 years (6·7-9·9) overall, while having the smallest reduction in life expectancy due to COVID-19 (0·4 years). The largest reduction in life expectancy due to COVID-19 occurred in Latin America and the Caribbean (3·6 years). Additionally, 53 of the 288 causes of death were highly concentrated in locations with less than 50% of the global population as of 2021, and these causes of death became progressively more concentrated since 1990, when only 44 causes showed this pattern. The concentration phenomenon is discussed heuristically with respect to enteric and lower respiratory infections, malaria, HIV/AIDS, neonatal disorders, tuberculosis, and measles. INTERPRETATION Long-standing gains in life expectancy and reductions in many of the leading causes of death have been disrupted by the COVID-19 pandemic, the adverse effects of which were spread unevenly among populations. Despite the pandemic, there has been continued progress in combatting several notable causes of death, leading to improved global life expectancy over the study period. Each of the seven GBD super-regions showed an overall improvement from 1990 and 2021, obscuring the negative effect in the years of the pandemic. Additionally, our findings regarding regional variation in causes of death driving increases in life expectancy hold clear policy utility. Analyses of shifting mortality trends reveal that several causes, once widespread globally, are now increasingly concentrated geographically. These changes in mortality concentration, alongside further investigation of changing risks, interventions, and relevant policy, present an important opportunity to deepen our understanding of mortality-reduction strategies. Examining patterns in mortality concentration might reveal areas where successful public health interventions have been implemented. Translating these successes to locations where certain causes of death remain entrenched can inform policies that work to improve life expectancy for people everywhere. FUNDING Bill & Melinda Gates Foundation

Access to Dry Season Agricultural Content in the Broadcast Media and Dry Season Irrigation Farming among Smallholder Farmers in Nigeria

Inaccessibility to information could hinder the adoption of dry season agriculture which is very significant to ending the spate of food insecurity in Nigeria. This cross-sectional survey examined access to broadcast media agricultural content and the effect of such information on dry season agriculture practice among smallholder farmers in Nigeria’s Federal Capital Territory (FCT). Participants consisted of 381 smallholder farmers selected from rural settlements in Kuje and Kwali Area councils, through a multi-stage sampling procedure. Data for the study was generated via a self-designed questionnaire. The findings of this study show that access to the broadcast media agricultural content is high (94.2%) in the FCT and the majority (83.1%) of the farmers are particularly exposed to agricultural programmes on dry season farming. However, the regularity of exposure to such programmes is considered rare/occasional by a sizable proportion (44.8%) of the selected farmers. The research further confirms the general acceptability of the broadcast programmes on dry season agriculture but the major snag is that the majority (>50%) of the farmers think that the time at which the information is broadcast is inappropriate. In terms of the practical implications of the programmes, findings also revealed that 50%) remain adamant that dry-season farming is not achievable and productive; therefore, they have not engaged in dry season irrigation agriculture. We concluded that the knowledge gained from the dry season agricultural programmes in the broadcast media is not sufficient for farmers to successfully engage in dry season irrigation farming. The study recommends a long-term and sustained media campaign on dry season farming, the use of interactive programme content, and rescheduling agricultural programmes to farmers’ preferred time could yield the desired impact on dry season irrigation farming and food security in Nigeria

Potentials of plantain peel and Tithonia diversifolia leaves as soil amendments in enhancing performance and nutritional contents of tomato (Solanum lycopersicum)

Screen house experiment was conducted in 2020 at the Landmark University Teaching and Research Farm Omu-aran, Kwara State. The experiment was carried out to evaluate the potential of dried unripe plantain peel and Tithonia diversifolia as soil amendments and its effect on growth, yield and fruit quality of tomato. Four rates each of dried plantain peel (0, 5, 10 and 15 t/ha) and Tithonia diversifolia (0, 10, 20 and 30 t/ha) were applied sole and combined. The experimental layout was a completely randomized design (CRD) with three replicates. Parameters were collected on the plant height, number of leaves, number of branches, stem girth, yield and fruit quality. Data collected were subjected to Analysis of variance (ANOVA) using the GENSTAT Discovery Software, Edition 4. Comparison of the treatment means were carried out using Duncan Multiple range test (DMRT) at 0.05 level of probability. Results showed that dried plantain peel and Tithonia diversifolia improved, number and weight of fruits as well as the fruit quality of tomato and were comparable to the application of NPK fertilizer. Treatment P5T30 (T8) increased number of leaves and number of branches while P15T20 (T15) and P10T30 (T12) increased plant height and stem girth respectively. Treatment P5T30 (T8) and P10T20 (T11) also significantly improved the fruit quality (minerals, lycopene and Vit. A) of tomato fruits. It can therefore be concluded that application of dried plantain peel and Tithonia diversifolia at P5T30 (T8) and P10T20 (T11) increased the vegetative, yield and quality parameters of tomato in the screen house of the study area

Biochar, poultry manure and NPK fertilizer: sole and combine application effects on soil properties and ginger (Zingiber officinale Roscoe) performance in a tropical Alfisol

Biochar has a low chemical composition and is recalcitrant to degradation. For good soil fertility and nutrient use efficiency of crops it becomes imperative that addition of a fast releasing nutrient source to biochar be sought. Therefore, studies were conducted in 2017 and 2018 to evaluate the effects of biochar with poultry manure (PM) and NPK fertilizer on soil properties, growth and yield of ginger. Treatments evaluated were: biochar applied alone at 15 t ha-1 , PM applied alone at 15 t ha-1, NPK fertilizer applied alone at 200 kg ha-1, biochar applied at 15 t ha-1 with poultry manure applied at 15 t ha-1 (B+PM), biochar applied at 15 t ha-1 with NPK fertilizer applied at 200 kg ha-1 (B+NPK) and a control with no amendment whatsoever. The experimental design was a randomized complete block design with three replications. Biochar, PM, NPK fertilizer alone or B+PM and B+NPK improved soil physical and chemical properties, growth and yield of ginger compared to no amendment (control). NPK fertilizer did not improve soil physical properties nor increased pH, OM, Ca and Mg significantly. B+PM and B+NPK improved soil physical and chemical properties, growth and ginger yield compared to their sole forms. Although B+PM had better soil physical properties, B+NPK increased yield and growth of ginger compared to B+PM. B+NPK increased the yield of ginger by 12.2% and 10.6% in 2017 and 2018, respectively compared with B+PM. B+NPK also increased the yield of ginger by 49.2% and 50.3% in 2017 and 2018, respectively compared to biochar alone. This was related to high presence of nutrients in B+NPK especially N and K which are important for ginger rhizome formation