Produção de suínos em sistema de ciclo completo: custos e receitas da utilização dos dejetos.

Este trabalho teve como objetivo estimar os custos de distribuição dos dejetos de uma criação de suínos com 42 matrizes em sistema de ciclo completo e as receitas obtidas do seu uso como substituto dos fertilizante químicos. Foram definidas as quantidades de dejetos produzidas, a área de aplicação e os custos de transporte. Posteriormente estimadas as receitas que os dejetos gerariam substituindo fertilizantes químicos como a uréia, o super triplo e o cloreto de potássio.bitstream/item/111047/1/Cot474.pd

Ca2+ signals critical for egress and gametogenesis in malaria parasites depend on a multipass membrane protein that interacts with PKG.

Calcium signaling regulated by the cGMP-dependent protein kinase (PKG) controls key life cycle transitions in the malaria parasite. However, how calcium is mobilized from intracellular stores in the absence of canonical calcium channels in Plasmodium is unknown. Here, we identify a multipass membrane protein, ICM1, with homology to transporters and calcium channels that is tightly associated with PKG in both asexual blood stages and transmission stages. Phosphoproteomic analyses reveal multiple ICM1 phosphorylation events dependent on PKG activity. Stage-specific depletion of Plasmodium berghei ICM1 prevents gametogenesis due to a block in intracellular calcium mobilization, while conditional loss of Plasmodium falciparum ICM1 is detrimental for the parasite resulting in severely reduced calcium mobilization, defective egress, and lack of invasion. Our findings suggest that ICM1 is a key missing link in transducing PKG-dependent signals and provide previously unknown insights into atypical calcium homeostasis in malaria parasites essential for pathology and disease transmission

From fixed-length to arbitrary-length rsa encoding schemes revisited

Abstract. To sign with RSA, one usually encodes the message m as µ(m) and then raises the result to the private exponent modulo N. In Asiacrypt 2000, Coron et al. showed how to build a secure RSA encoding scheme µ ′ (m) for signing arbitrarily long messages from a secure encoding scheme µ(m) capable of handling only fixed-size messages, without making any additional assumptions. However, their construction required that the input size of µ be larger than the modulus size. In this paper we present a construction for which the input size of µ does not have to be larger than N. Our construction shows that the difficulty in building a secure encoding for RSA signatures is not in handling messages of arbitrary length, but rather in finding a secure encoding function for short messages, which remains an open problem in the standard model.

Geochronological and geochemical studies of mafic and intermediate dykes from the Khao Khwang Fold–Thrust Belt: Implications for petrogenesis and tectonic evolution

Zircon U–Pb, mica 40Ar/39Ar ages and geochemistry of the Permo-Triassic mafic to intermediate dyke swarms at the south-western margin of the Indochina Terrane, central Thailand, are reported here and used to decipher the timing of the Sukhothai-Indochina & Sibumasu-Indochina collisions during the Permo-Triassic stages of the Indosinian Orogeny. The mafic dyke swarms in the folded layers of the Khao Khwang Fold–Thrust Belt (KKFTB) were emplaced between the Late Permian and the Late Triassic. The volcanic rocks range from slightly tholeiitic to mostly calc-alkalic, but can be subdivided into three different volcanic groups on the basis of trace and incompatible element abundances such as Ni, Cr, P, Co, and Th. However, all the groups present similar chemical footprints and are enriched in large ion lithophile elements (LILEs) (Rb, Ba, Sr, Pb) and light rare earth elements (LREEs), and depleted in HFSE such as Nb, and Ti highlighting the volcanic arc nature of the system. Isotopically, the three groups are characterized by subtle differences in εNd(t) values (from + 3.2 to + 5.2) and initial 87Sr/86Sr ratios (from 0.7056 to 0.7067). The KKFTB mafic dykes share a few geochemical characteristics of the mafic dykes from the Chiang Khong volcanic suite in the Sukhothai terrane, and from the Loei volcanic belt in northern Indochina. These geochemical features suggest that the KKFTB mafic dykes, and the volcanic rocks in central-northern Thailand, were likely emplaced in a similar orogenic setting. The rocks of Group III are interpreted to have intruded from the Early Triassic (255 ± 6 Ma) to the Late Triassic (207 ± 2 Ma), and were probably sourced from a more crustally contaminated magma