Synthesis of 2-arylbenzothiazoles using nano BF₃/SiO₂ as a reusable and efficient heterogeneous catalyst under mild conditions

<div><p>2-Arylbenzothiazoles were synthesized via condensation of 2-aminothiophenol and different aldehydes catalyzed by nano silica-supported boron trifluoride (nano BF₃/SiO₂) as an efficient and reusable catalyst in high yields and short reaction times. The reactions proceeded at room temperature under mild conditions to afford 2-arylbenzothiazole derivatives. The pure products were identified and characterized by physical and spectroscopic data such as IR, ¹H NMR, ¹³C NMR and Mass spectroscopy.</p></div

Facile one-pot synthesis of 2-arylbenzothiazoles catalyzed by H₃PO₄/TiO₂-ZrO₂ (1/1) under solvent-free conditions

<p>A highly efficient and simple protocol for the preparation of 2-arylbenzothiazoles through condensation of 2-aminothiophenol and different aldehydes in the presence of H₃PO₄/TiO₂-ZrO₂(1/1)-cetyl pyridinium bromide (CPB) is described. The reaction proceeded under mild and solvent-free conditions to afford 2-arylbenzothiazole derivatives. In this method, the title compounds were obtained in good to excellent yields and short reaction times. The structures of synthesized products were identified by infrared, ¹H NMR, ¹³C NMR, and mass spectroscopy.</p

A Man with Pancreatic Head Mass Lesion on Endoscopic Ultrasound and Granuloma on Cytopathology

Primary pancreatic lymphoma is an unlikely malignancy accounting for less than 0.5% of pancreatic tumors. Clinical presentation is often nonspecific and may be clinically misdiagnosed as pancreatic adenocarcinoma. Here we present an Iranian case of primary pancreatic lymphoma in a 47-year-old male suffering from jaundice and 20% weight loss. Endoscopic ultrasound revealed a mixed echoic mass lesion at the head of pancreas. The patient underwent endoscopic ultrasound-guided fine needle aspiration of solid pancreatic mass and histopathologic diagnosis revealed granuloma. Computed tomography-guided core needle biopsy was performed and eventually histological examination showed granuloma that was coherent with the diagnosis of primary pancreatic lymphoma. Primary pancreatic lymphoma is a rare entity presenting with nonspecific symptoms, laboratory and radiological findings. Computed tomography results in combination with clinical and radiological studies generally provide guidance for appropriate investigation