31 research outputs found
Mutations of the human thyrotropin-Ăź subunit glycosylate site reduce thyrotropin synthesis independent of changes in glycosylate status
Análise da translação anterior da tĂbia, pico de torque e atividade eletromiográfica do quadrĂceps e isquiotibiais em indivĂduos com lesĂŁo do ligamento cruzado anterior em cadeia cinĂ©tica aberta
Magnetosome Formation in Prokaryotes
Magnetotactic bacteria were discovered almost 30 years ago, and for many years and many different reasons, the number of researchers working in this field was few and progress was slow. Recently, however, thanks to the isolation of new strains and the development of new techniques for manipulating these strains, researchers from several laboratories have made significant progress in elucidating the molecular, biochemical, chemical and genetic bases of magnetosome formation and understanding how these unique intracellular organelles function. We focus here on this progress
Infection polymorphism and cytoplasmic incompatibility in Hymenoptera-Wolbachia associations
Infection polymorphism and cytoplasmic incompatibility in Hymenoptera-Wolbachia associations
Progress in the Development Of Natural Products for Human Immunodeficiency Viruses Infections
Salivary biomarkers in cancer detection
Cancer is the second most common cause of death in the USA. Its symptoms are often not specific and absent, until the tumors have already metastasized. Therefore, there is an urgent demand for developing rapid, highly accurate and noninvasive tools for cancer screening, early detection, diagnostics, staging and prognostics. Saliva as a multi-constituent oral fluid comprises secretions from the major and minor salivary glands, extensively supplied by blood. Molecules such as DNAs, RNAs, proteins, metabolites, and microbiota, present in blood, could be also found in saliva. Recently, salivary diagnostics has drawn significant attention for the detection of specific biomarkers, since the sample collection and processing are simple, cost-effective, and precise and do not cause patient discomfort. Here, we review recent salivary candidate biomarkers for systemic cancers by dividing them according to their origin into: genomic, transcriptomic, proteomic, metabolomic and microbial types