747 research outputs found
Spin-dependent thermoelectric transport coefficients in near-perfect quantum wires
Thermoelectric transport coefficients are determined for semiconductor
quantum wires with weak thickness fluctuations. Such systems exhibit anomalies
in conductance near 1/4 and 3/4 of 2e^2/h on the rising edge to the first
conductance plateau, explained by singlet and triplet resonances of conducting
electrons with a single weakly bound electron in the wire [T. Rejec, A. Ramsak,
and J.H. Jefferson, Phys. Rev. B 62, 12985 (2000)]. We extend this work to
study the Seebeck thermopower coefficient and linear thermal conductance within
the framework of the Landauer-Buettiker formalism, which also exhibit anomalous
structures. These features are generic and robust, surviving to temperatures of
a few degrees. It is shown quantitatively how at elevated temperatures thermal
conductance progressively deviates from the Wiedemann-Franz law.Comment: To appear in Phys. Rev. B 2002; 3 figure
Lack of correlation of stem cell markers in breast cancer stem cells
BACKGROUND: Various markers are used to identify the unique sub-population of breast cancer cells with stem cell properties. Whether these markers are expressed in all breast cancers, identify the same population of cells, or equate to therapeutic response is controversial. METHODS: We investigated the expression of multiple cancer stem cell markers in human breast cancer samples and cell lines in vitro and in vivo, comparing across and within samples and relating expression with growth and therapeutic response to doxorubicin, docetaxol and radiotherapy. RESULTS: CD24, CD44, ALDH and SOX2 expression, the ability to form mammospheres and side-population cells are variably present in human cancers and cell lines. Each marker identifies a unique rather than common population of cancer cells. In vivo, cells expressing these markers are not specifically localized to the presumptive stem cell niche at the tumour/stroma interface. Repeated therapy does not consistently enrich cells expressing these markers, although ER-negative cells accumulate. CONCLUSIONS: Commonly employed methods identify different cancer cell sub-populations with no consistent therapeutic implications, rather than a single population of cells. The relationships of breast cancer stem cells to clinical parameters will require identification of specific markers or panels for the individual cancer
Commensurability oscillations in the rf conductivity of unidirectional lateral superlattices: measurement of anisotropic conductivity by coplanar waveguide
We have measured the rf magnetoconductivity of unidirectional lateral
superlattices (ULSLs) by detecting the attenuation of microwave through a
coplanar waveguide placed on the surface. ULSL samples with the principal axis
of the modulation perpendicular (S_perp) and parallel (S_||) to the microwave
electric field are examined. For low microwave power, we observe expected
anisotropic behavior of the commensurability oscillations (CO), with CO in
samples S_perp and S_|| dominated by the diffusion and the collisional
contributions, respectively. Amplitude modulation of the Shubnikov-de Haas
oscillations is observed to be more prominent in sample S_||. The difference
between the two samples is washed out with the increase of the microwave power,
letting the diffusion contribution govern the CO in both samples. The failure
of the intended directional selectivity in the conductivity measured with high
microwave power is interpreted in terms of large-angle electron-phonon
scattering.Comment: 8 pages, 5 figure
Trouble at the top: The construction of a tenant identity in the governance of social housing organizations
The project of citizen governance has transformed the social housing sector in England where 20,000 tenants now sit as directors on the boards of housing associations, but the entrance of social housing tenants to the boardroom has aroused opposition from the chief executives of housing companies and triggered regulatory intervention from government inspectors. This paper investigates the cause of these tensions through a theoretical framework drawn from the work of feminist philosopher Judith Butler. It interprets housing governance as an identificatory project with the power to constitute tenant directors as regulated subjects, and presents evidence to suggest that this project of identity fails to completely enclose its subject, allowing tenant directors to engage in ‘identity work’ that threatens the supposed unity of the board. The paper charts the development of antagonism and political tension in the board rooms of housing companies to present an innovative account of the construction and contestation of identities in housing governance
Interaction Effects in a One-Dimensional Constriction
We have investigated the transport properties of one-dimensional (1D)
constrictions defined by split-gates in high quality GaAs/AlGaAs
heterostructures. In addition to the usual quantized conductance plateaus, the
equilibrium conductance shows a structure close to , and in
consolidating our previous work [K.~J. Thomas et al., Phys. Rev. Lett. 77, 135
(1996)] this 0.7 structure has been investigated in a wide range of samples as
a function of temperature, carrier density, in-plane magnetic field
and source-drain voltage . We show that the 0.7
structure is not due to transmission or resonance effects, nor does it arise
from the asymmetry of the heterojunction in the growth direction. All the 1D
subbands show Zeeman splitting at high , and in the wide channel
limit the -factor is , close to that of bulk GaAs.
As the channel is progressively narrowed we measure an exchange-enhanced
-factor. The measurements establish that the 0.7 structure is related to
spin, and that electron-electron interactions become important for the last few
conducting 1D subbands.Comment: 8 pages, 7 figures (accepted in Phys. Rev. B
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