Superlattice nonlinearities for Gigahertz-Terahertz generation in harmonic multipliers

Semiconductor superlattices are strongly nonlinear media offering several technological challenges associated with the generation of high-frequency Gigahertz radiation and very effective frequency multiplication up to several Terahertz. However, charge accumulation, traps and interface defects lead to pronounced asymmetries in the nonlinear current flow, from which high harmonic generation stems. This problem requires a full non-perturbative solution of asymmetric current flow under irradiation, which we deliver in this paper within the Boltzmann-Bloch approach. We investigate the nonlinear output on both frequency and time domains and demonstrate a significant enhancement of even harmonics by tuning the interface quality. Moreover, we find that increasing arbitrarily the input power is not a solution for high nonlinear output, in contrast with materials described by conventional susceptibilities. There is a complex combination of asymmetry and power values leading to maximum high harmonic generation.Comment: 13 pages, 7 figures, Accepted for Nanophotonics (De Gruyter

Controlling the harmonic conversion efficiency in semiconductor superlattices by interface roughness design

In semiconductor superlattices, when Bragg oscillating electrons interact with an input electromagnetic field, frequency multiplication is possible. An ideal superlattice has a purely antisymmetric voltage current response and can thus produce only odd harmonics. However, real world superlattices can also have even harmonic response and that increases the range of possible output frequencies. These effects have been recently explained with a predictive model that combines an Ansatz solution for the Boltzmann Equation with a Nonequilibrium Green's Functions approach. This predictive tool, coupled with recent progress on GHz input sources, support the growing interest in developing compact room temperature devices that can operate from the GHz to the THz range. The natural question to ask is what efficiencies can be expected. This paper addresses this issue by investigating power-conversion efficiency in irradiated semiconductor superlattices. Interface imperfections are consistently included in the theory and they strongly influence the power output of both odd and even harmonics. Good agreement is obtained for predicted odd harmonic outputs with experimental data for a wide frequency range. The intrinsic conversion efficiency used is based on the estimated amplitude of the input field inside the sample and thus independent of geometrical factors that characterize different setups. The method opens the possibility of designing even harmonic output power by controlling the interface quality

Photo-acoustic spectroscopy using a quantum cascade laser (QCL) for analysis of ammonia in water solutions

Ammonia (NH$_3$) toxicity, stemming from nitrification, can adversely affect aquatic life and influence the taste and odor of drinking water. This underscores the necessity for highly responsive and accurate sensors to continuously monitor NH$_3$ levels in water, especially in complex environments where reliable sensors have been lacking until this point. Herein, we detail the development of a sensor comprising a compact and selective analyzer with low gas consumption and a timely response, based on photoacoustic spectroscopy. This, combined with an automated liquid sampling system, enables the precise detection of ammonia traces in water. The sensor system incorporates a state-of-the art quantum cascade laser as the excitation source emitting at 9 \textmu m in resonance with the absorption line of NH$_3$ located at 1103.46 cm$^{-1}$. Our instrument demonstrated detection sensitivity at low ppm level for total ammonia nitrogen with response times less than 60 seconds. For the sampling system, an ammonia stripping solution was designed resulting in a prompt full measurement cycle (6.35 mins). A further evaluation of the sensor within a pilot study showed good reliability and agreement with the reference method for real water samples, confirming the potential of our NH$_3$ analyzer for water-quality monitoring applications.Comment: In total:15 pages,13 figures. main paper:9 pages(9 pages,9 figures:8 figures + 1 graphical abstract-figure), supporting information: 6 pages, 4 figure

Structural and biomechanical alterations in rabbit thoracic aortas are associated with the progression of atherosclerosis

<p>Abstract</p> <p>Background</p> <p>Atherosclerosis is a diffuse and highly variable disease of arteries that alters the mechanical properties of the vessel wall through highly variable changes in its cellular composition and histological structure. We have analyzed the effects of acute atherosclerotic changes on the mechanical properties of the descending thoracic aorta of rabbits fed a 4% cholesterol diet.</p> <p>Methods</p> <p>Two groups of eight male New Zealand White rabbits were randomly selected and fed for 8 weeks either an atherogenic diet (4% cholesterol plus regular rabbit chow), or regular chow. Animals were sacrificed after 8 weeks, and the descending thoracic aortas were excised for pressure-diameter tests and histological evaluation to examine the relationship between aortic elastic properties and atherosclerotic lesions.</p> <p>Results</p> <p>All rabbits fed the high-cholesterol diet developed either intermediate or advanced atherosclerotic lesions, particularly American Heart Association-type III and IV, which were fatty and contained abundant lipid-filled foam cells (RAM 11-positive cells) and fewer SMCs with solid-like actin staining (HHF-35-positive cells). In contrast, rabbits fed a normal diet had no visible atherosclerotic changes. The atherosclerotic lesions correlated with a statistically significant decrease in mean vessel wall stiffness in the cholesterol-fed rabbits (51.52 ± 8.76 kPa) compared to the control animals (68.98 ± 11.98 kPa), especially in rabbits with more progressive disease.</p> <p>Conclusions</p> <p>Notably, stiffness appears to decrease with the progression of atherosclerosis after the 8-week period.</p

System for classifying antibody concentration against severe acute respiratory syndrome coronavirus 2 S1 spike antigen with automatic quick response generation for integration with health passports

Aim: After the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic and the realization of mass vaccination against the virus, the availability of a reliable, rapid, and easy-to-use system for registering the individual anti-S1 antibody titer could facilitate the personalized assessment of the need for booster vaccine doses and the reduction of social distancing and other measures. Methods: The biosensor system is based on immobilized engineered SK-N-SH neuroblastoma cells, bearing the S1 protein, and it can detect immunoglobulin G (IgG) antibodies against the SARS-CoV-2 S1 spike antigen. A disposable electrode strip bearing the engineered mammalian cells is connected to a customized read-out potentiometric device with real-time data transmission to a wireless fidelity (WiFi)-connected smartphone. Blood samples from past-infected individuals and individuals vaccinated against SARS-CoV-2 were used for validation. Results: In the present study, a smartphone application (app), capable of analyzing data regarding the levels of anti-S1 antibodies in blood is introduced. The app works in conjunction with a portable, ultra-rapid, and sensitive biosensor transmitting real-time measurements to the smartphone. Both historical and current individual data can be encoded by using the app, resulting in a widely accepted quick response (QR) code, which can then be constantly updated to match a person’s status. Conclusions: This novel system could be utilized for the eventual development of a coronavirus disease 2019 (COVID-19) electronic passport, which could be further employed to improve the population-wide, cross-country surveillance of vaccination efficiency, as well as facilitate the implementation of cross-border digital health services in a user-friendly and secure way

Study of Single and Multipass f&ndash;rGO Inkjet-Printed Structures with Various Concentrations: Electrical and Thermal Evaluation

Reduced graphene oxide (rGO) is a derivative of graphene, which has been widely used as the conductive pigment of many water-based inks and is recognized as one of the most promising graphene-based materials for large-scale and low-cost production processes. In this work, we evaluate a custom functionalised reduced graphene oxide ink (f&ndash;rGO) via inkjet-printing technology. Test line structures were designed and fabricated by the inkjet printing process using the f&ndash;rGO ink on a pretreated polyimide substrate. For the electrical characterisation of these devices, two-point (2P) and four-point (4P) probe measurements were implemented. The results showed a major effect of the number of printed passes on the resulting resistance for all ink concentrations in both 2P and 4P cases. Interesting results can be extracted by comparing the obtained multipass resistance values that results to similar effective concentration with less passes. These measurements can provide the ground to grasp the variation in resistance values due to the different ink concentrations, and printing passes and can provide a useful guide in achieving specific resistance values with adequate precision. Accompanying topography measurements have been conducted with white-light interferometry. Furthermore, thermal characterisation was carried out to evaluate the operation of the devices as temperature sensors and heaters. It has been found that ink concentration and printing passes directly influence the performance of both the temperature sensors and heaters

High-frequency acoustoelectronic phenomena in miniband superlattices

The motion of a quantum particle in a periodic potential can generate rich dynamics in the presence of a driving field. Such systems include, but are not limited to, semiconductor superlattices which exhibit a very anisotropic band structure that results into pronounced nonlinearities and high carrier mobility. In this thesis, we investigate the semiclassical dynamics and electron transport in a spatially periodic potential driven by a propagating wave. Firstly, we examine the transport features of an electron in a single miniband superlattice driven by a high-frequency acoustic plane wave. In this system, the nonlinear electron dynamics crucially depends on the amplitude of the acoustic wave. The transport characteristics are studied by means of a non-linearised kinetic model. In particular, to provide a realistic description of the directed transport, we employ the exact path-integral solutions of the Boltzmann transport equation. The calculated electron drift velocity and the time-averaged velocity show a nonmonotonic dependence upon the amplitude of the acoustic wave with multiple pronounced extrema. We found out that the changes in the velocity-amplitude characteristics are directly associated with a series of global bifurcations due to topological rearrangements of the phase space of the system. These dramatic transformations are connected with superlattice intraminiband transitions, and accompanied by inelastic emission (absorption) of the quantum particle. The bifurcations also signify the transitions between different dynamical regimes, involving unconfined electron motion, wave-dragging and phonon-assisted Bloch oscillations. Each regime has a characteristic spectral fingerprint, which manifests itself in appearance of specific high-frequency components in the spectra of the corresponding averaging trajectory. Secondly, we consider to use the acoustically pumped superlattices for an amplification of THz electromagnetic waves, involving the mechanisms similar to the Bloch gain in electrically biased superlattices. In particular, we predict the tunable THz gain due to nonlinear oscillations which are associated with the localised motion of electrons confined by a propagating potential wave. Traditionally, one of the key issues which emerges from considering different schemes for achieving small signal gain in superlattices, is the control of electric stability. Here, it is shown that for our case of the fast miniband electrons driven by an acoustic wave, terahertz gain can occur without the electric instability. Additionally, we find that the characteristic changes in the averaged velocities are connected to the shape of gain profiles. Consequently, the analytic findings, which determine the transitions between different dynamical regimes at the bifurcations, hold up for the behaviour of amplification of high-frequency electromagnetic waves. The increase of the miniband width, results in an enhancement of the effect of phase space restructuring on the drift velocity and high-frequency gain. Finally, we analyse the case for a superlattice device utilising acoustic waves with a very slow propagation speed. Benefiting from a simple solution of the Boltzmann equation, here we clarify the role of spatial nonlinearity both in miniband electron dynamics and in amplification of an electromagnetic wave. We show that nonlinear Bloch oscillations occur at a single critical value of the wave amplitude, inducing high negative differential drift velocity. Within this model, we also explain how the amplification of a high-frequency signal can arise below the threshold for an excitation of Bloch oscillations

Superlattice nonlinearities for Gigahertz-Terahertz generation in harmonic multipliers

Abstract Semiconductor superlattices are strongly nonlinear media offering several technological challenges associated with the generation of high-frequency Gigahertz radiation and very effective frequency multiplication up to several Terahertzs. However, charge accumulation, traps and interface defects lead to pronounced asymmetries in the nonlinear current flow, from which high harmonic generation stems. This problem requires a full non-perturbative solution of asymmetric current flow under irradiation, which we deliver in this paper within the Boltzmann-Bloch approach. We investigate the nonlinear output on both frequency and time domains and demonstrate a significant enhancement of even harmonics by tuning the interface quality. Moreover, we find that increasing arbitrarily the input power is not a solution for high nonlinear output, in contrast with materials described by conventional susceptibilities. There is a complex combination of asymmetry and power values leading to maximum high harmonic generation.</jats:p