Digital detox: An effective solution in the smartphone era? A systematic literature review

Smartphone use, e.g., on social network sites or instant messaging, can impair well-being and is related to clinical phenomena, like depression. Digital detox interventions have been suggested as a solution to reduce negative impacts from smartphone use on outcomes like well-being or social relationships. Digital detox is defined as timeouts from using electronic devices (e.g., smartphones), either completely or for specific subsets of smartphone use. However, until now, it has been unclear whether digital detox interventions are effective at promoting a healthy way of life in the digital era. This systematic literature review aimed to answer the question of whether digital detox interventions are effective at improving outcomes like health and well-being, social relationships, self-control or performance. Systematic searches of seven databases were carried out according to PRISMA guidelines, and intervention studies were extracted that examined timeouts from smartphone use and/or smartphone-related use of social network sites and instant messaging. The review yielded k = 21 extracted studies (total N = 3,625 participants). The studies included interventions in the field, from which 12 were identified as randomized controlled trials. The results showed that the effects from digital detox interventions varied across studies on health and well-being, social relationships, self-control, or performance. For example, some studies found positive intervention effects, whereas others found no effect or even negative consequences for well-being. Reasons for these mixed findings are discussed. Research is needed to examine mechanisms of change to derive implications for the development of successful digital detox interventions

Digital detox: An effective solution in the smartphone era? A systematic literature review

Smartphone use, e.g., on social network sites or instant messaging, can impair well-being and is related to clinical phenomena, like depression. Digital detox interventions have been suggested as a solution to reduce negative impacts from smartphone use on outcomes like well-being or social relationships. Digital detox is defined as timeouts from using electronic devices (e.g., smartphones), either completely or for specific subsets of smartphone use. However, until now, it has been unclear whether digital detox interventions are effective at promoting a healthy way of life in the digital era. This systematic literature review aimed to answer the question of whether digital detox interventions are effective at improving outcomes like health and well-being, social relationships, self-control or performance. Systematic searches of seven databases were carried out according to PRISMA guidelines, and intervention studies were extracted that examined timeouts from smartphone use and/or smartphone-related use of social network sites and instant messaging. The review yielded k = 21 extracted studies (total N = 3,625 participants). The studies included interventions in the field, from which 12 were identified as randomized controlled trials. The results showed that the effects from digital detox interventions varied across studies on health and well-being, social relationships, self-control, or performance. For example, some studies found positive intervention effects, whereas others found no effect or even negative consequences for well-being. Reasons for these mixed findings are discussed. Research is needed to examine mechanisms of change to derive implications for the development of successful digital detox interventions

The Human Serum Metabolome

Continuing improvements in analytical technology along with an increased interest in performing comprehensive, quantitative metabolic profiling, is leading to increased interest pressures within the metabolomics community to develop centralized metabolite reference resources for certain clinically important biofluids, such as cerebrospinal fluid, urine and blood. As part of an ongoing effort to systematically characterize the human metabolome through the Human Metabolome Project, we have undertaken the task of characterizing the human serum metabolome. In doing so, we have combined targeted and non-targeted NMR, GC-MS and LC-MS methods with computer-aided literature mining to identify and quantify a comprehensive, if not absolutely complete, set of metabolites commonly detected and quantified (with today's technology) in the human serum metabolome. Our use of multiple metabolomics platforms and technologies allowed us to substantially enhance the level of metabolome coverage while critically assessing the relative strengths and weaknesses of these platforms or technologies. Tables containing the complete set of 4229 confirmed and highly probable human serum compounds, their concentrations, related literature references and links to their known disease associations are freely available at http://www.serummetabolome.ca

Hausarbeit im Öffentlichen Recht für Anfänger - Nach der Demo wird es teuer

Der Fall wurde als Hausarbeit im Rahmen der Übung im öffentlichen Recht für Anfänger im Wintersemester 2019/2020 an der Abteilung Rechtswissenschaft der Universität Mannheim gestellt. Der Fall ist an die Ereignisse in Hamburg während des G-20-Gipfels im Jahr 2017 angelehnt. Die Schwerpunkte der Hausarbeit lagen in der Prüfung der Verfassungsmäßigkeit der zivilrechtlichen Haftungsbestimmungen für Schäden bei Versammlungen sowie in der Prüfung der verfassungskonformen Anwendung der §§ 830, 840 BGB durch die Zivilgerichte im Einzelfall