Flow chart of the data collection of eating disorder study in males of FinnTwin16 cohorts.

<p>* Excluded N = 10 men whose low BMI resulted from missing limbs or tetraplegia; or other severe physical illness (multiple sclerosis, cerebral palsy).</p

Characteristics of the male anorexia nervosa probands and their co-twins in the population-based FinnTwin16 study.

<p><i>Note</i>: ¹Purging,²Non-purging</p

Autoimmune disease status per each individual autoimmune disease included in the study at the end of the study period (covering the time before, during and after the treatment) for a composite of all patients with eating disorder compared with their control individuals.

<p>Odds Ratios (OR) are presented if meaningful analyses were possible.</p

Period prevalences and results from conditional logistic regression models of autoimmune diseases from the start of the study period until the beginning of the treatment of an eating disorder.

<p>For the seven separate autoimmune disease categories presented, each participant counts as maximum one observation per category. For the total figure of any autoimmune disease, each participant is presented as maximum one observation. Out of all patients and all controls, there was only one patient participant (with bulimia nervosa) with pulmonary disease (not shown). CI, Confidence Interval; OR, Odds ratio.</p

Lifetime prevalences of autoimmune diseases, i.e. status at the end of the study period covering the time before, during and after the treatment for an eating disorder in patients with eating disorders compared with their control individuals.

<p>Lifetime prevalences of autoimmune diseases, i.e. status at the end of the study period covering the time before, during and after the treatment for an eating disorder in patients with eating disorders compared with their control individuals.</p

Study sample by diagnostic groups with lifetime prevalence figures of autoimmune diseases covering the time before, during, and after the treatment for an eating disorder.

<p>Each participant is presented as one observation, i.e. some autoimmune disease-positive individuals had more than one autoimmune disease. ED, Eating Disorder.</p

Incidence of new onset autoimmune diseases after the start of the treatment for an eating disorder until the end of the study period.

<p>Each participant accounted as maximum one observation per autoimmune disease category (according to the first incident autoimmune disease).Those who already had had an autoimmune disease (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0104845#pone-0104845-t002" target="_blank">Table 2</a>) included in each category, were excluded. In the section of ‘<i>Any autoimmune disease</i>’<b>,</b> those who had had any previous autoimmune disease were excluded. There were no incident cases in pulmonary diseases. CI, Confidence Interval; RR, Risk Ratio.</p><p>*Statistically significant P-values.</p