Individual and mean rPDC values at different stages of the study.

<p>Individual fronto-occipital (F3–O1, F4–O2) 10–20 Hz and occipito-frontal (O1–F3, O2–F4) 8–16 Hz rPDC values during stepwise increased propofol infusion during the awake (AWA) state, sedation (SED), loss of consciousness (LOC) and return of consciousness (ROC). Individual and mean rPDC values are presented with thin and thick lines, respectively.</p

Directed connectivity between frontal and parietal brain regions.

<p>Fronto-parietal (F3–P3, F4–P4) (1a) and Fronto-occipital (F3–O1, F4–O2) (1b) directional connectivity during the awake (AWA) period compared to propofol-induced sedation (SED), propofol-induced loss of consciousness (LOC) and return of consciousness (ROC) after the termination of propofol infusion. The time frequency plot presents the number of subjects exceeding the significance level. Remark that the timeline between SED and LOC is almost continuous as all the subjects lost consciousness approximately 5 min after SED.</p

Renormalized partial directed coherence (rPDC) values during propofol infusion.

<p>With overall significant (p<0.05) ANOVA result, the p-values for paired comparisons are also given. The non-significant p-values (p>0.05) are given in brackets. Abbreviations: ANOVA  =  Analysis of variance, AWA  =  Awake, SED  =  Sedation, LOC  =  Loss of consciousness, ROC  =  Return of consciousness.</p><p>Renormalized partial directed coherence (rPDC) values during propofol infusion.</p