Increasing the CpG dinucleotide abundance in the HIV-1 genomic RNA inhibits viral replication

Additional file 1. Codon modification of nucleotides 22-261 in gag inhibits viral replication in SupT1 cells. SupT1 cells were infected with 10 ng of p24Gag for each indicated virus. The amount of infectious virus present at each time point was measured in TZM-bl cells. This is representative of three independent experiments