Evaluation of the efficacy of dentin hypersensitivity treatments - a systematic review and follow-up analysis

OBJECTIVES: To compare the treatments used to treat dentin hypersensitivity (DH), based on its efficacy and effect duration. METHODS: Medline/PubMed, Cochrane Library, EMBASE, and ClinicalTrials were searched for articles published between January 1st , 2008 and November 14th , 2018, in English, Portuguese or Spanish, reporting clinical trials, completed and with results. This systematic review protocol was registered in PROSPERO, number CRD42019121986. RESULTS: 74 randomized clinical trials were included in the systematic review, reporting patients from 16 to 65 years old, with a clinical diagnosis of DH, that evaluate the efficacy of a desensitizing product, compared to pre-treatment, used the evaporative method stimulation and the visual analogue scale. These studies evaluated 5366 patients and at least 9167 teeth. Seven follow-up periods were considered corresponding to an immediate, medium or long-time effect. 66 studies were included in the quantitative synthesis. Glutaraldehyde with HEMA, glass ionomer cements and Laser present significant immediate (until 7 days) DH reduction. Medium term (until 1 month) reduction was observed in stannous fluoride, glutaraldehyde with HEMA, hydroxyapatite, glass ionomer cements and Laser groups. Finally, long term significant reduction was seen at potassium nitrate, arginine, glutaraldehyde with HEMA, hydroxyapatite, adhesive systems, glass ionomer cements, and LASER. CONCLUSIONS: All active ingredients show efficacy in DH reduction in different follow-up times. Only in-office treatments are effective in immediate DH reduction, maintaining its efficacy over time. For long time effects, at home treatments can also be used. More standardized evaluation protocols should be implemented to increase the robustly of the results.info:eu-repo/semantics/publishedVersio

PRODUCTION OF CHI-CHARMONIUM VIA 300-GEV/C PION AND PROTON INTERACTIONS ON A LITHIUM TARGET

We present a measurement and comparison of the chi(c1) and chi(c2) production cross sections determined from interactions of 300-GeV/c pi+/- and p with a Li target. We find chi(c1)/chi(c2) production ratios of 0.52(+0.57/-0.27) and 0.08(+0.25/-0.15) from reactions induced by pi+/- and p, respectively

PRODUCTION OF J/PSI VIA PSI' AND CHI DECAY IN 300-GEV/C PROTON-NUCLEON AND PI+/--NUCLEON INTERACTIONS

The production of the chi2 and chi2 states of charmonium has been observed in 300 GeV/c pi+/-N and pN interactions. The fraction of the total inclusive J/psi production due to radiative chi decay has been determined to be 0.40 +/- 0.04, 0.37 +/- 0.03, and 0.30 +/- 0.04 for the pi+, pi-, and proton data, respectively. Total cross sections for chi1 and chi2 production of 131 +/- 18 +/- 14 and 188 +/- 30 +/- 21 nb/nucleon in the 300 GeV/c pi-N interactions have been obtained. By measuring the contributions to the J/psi production due to both psi’ and radiative chi decay, the cross sections for direct J/psi production have been determined to be 97 +/- 14, 102 +/- 14, and 89 +/- 12 nb/nucleon for pi+, pi-, and protons, respectively

MEASUREMENT OF J/PSI AND PSI' PRODUCTION IN 300-GEV/C PROTON, ANTIPROTON, AND PI+/- INTERACTIONS WITH NUCLEI

Hadroproduction of the J/psi and psi’ states has been studied in 300-GeV/c proton, antiproton, and pi+-Li interactions. Both total and differential cross sections in x(F) and p(T) have been measured for the J/psi for the pi+-, proton, and antiproton interactions. The ratio of psi’ to J/psi production has been determined for the four types of beam particles