2 research outputs found

    VEGFA expression correlates with drug sensitivity.

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    <p>Green and red colors represent negative and positive Spearman’s rank correlation coefficients between VEGFA levels and different anticancer drugs’ IC50 in the CCLE (A) and GDSC (B). A positive correlation with IC50 means that the drug is less effective; a negative correlation indicates that it is more effective when VEGFA expression is higher. p < 0.05 correlations are displayed.</p

    NQO1 expression correlates with 17-AAG effectiveness in multiple cancer types.

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    <p>Green color represents negative Spearman’s rank correlation coefficients between NQO1expression and 17-AAG EC50 in the CCLE (A) and IC50 (EC50 was not available) in GDSC (B). These results indicate that 17-AAG works better when NQO1 expression is higher. Only p < 0.05 correlations are shown.</p
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