13 research outputs found
Absolute Frequency Atlas from 915 nm to 985 nm based on Laser Absorption Spectroscopy of Iodine
This article reports on laser absorption spectroscopy of iodine gas between
915 nm and 985 nm. This wavelength range is scanned utilizing a narrow
linewidth and mode-hop-free tunable diode-laser whose frequency is actively
controlled using a calibrated wavelength meter. This allows us to provide an
iodine atlas that contains almost 10,000 experimentally observed reference
lines with an uncertainty of 50 MHz. For common lines, good agreement is found
with a publication by Gerstenkorn et al. [S. Gerstenkorn, P. Luc, Atlas du
spectre d'absorption de la molecule d'iode 14800-20000 cm, Paris:
Editions du Centre National de la Recherche Scientifique (CNRS), 1978]. The new
rich dataset allows existing models of the iodine molecule to be refined and
can serve as a reference for laser frequency calibration and stabilization.Comment: 7 pages, 4 figures, link to online data depositor
Additional file 6: of Copy number variations in Friesian horses and genetic risk factors for insect bite hypersensitivity
Chromosomal distribution, characteristics and enrichment of detected CNVs and CNVRs. Number of CNVs and CNVRs detected per Equus caballus chromosome (ECA), including detection, state, content, mean size (in base pairs), coverage (in base pairs), chromosomal distribution ( = number of CNVs per chromosome total number of CNVs × 100 % ), chromosomal coverage ( CNVR coverage per chromosome length of chromosome × 100 % ) and SNP coverage in base pairs ( = length of chromosome number of SNPs per chromosome ). (DOCX 24 kb
Additional file 3: of Copy number variations in Friesian horses and genetic risk factors for insect bite hypersensitivity
CNVs randomly selected based on incidence and size validated through qPCR. CNVR identification, chromosome (ECA), start and end position (in bp) and size of the CNVs in the investigated Friesians horse sample is presented, including information on whether the CNV concerned a private (present in 1 horse) or shared (present in 2 horses; the exact same breakpoints were observed) CNV. The designed primers, state of the CNV and results of the qPCR are given. (DOCX 14 kb
Additional file 2: of Copy number variations in Friesian horses and genetic risk factors for insect bite hypersensitivity
Multidimensional scaling plot of 276 genotyped Friesian horses. Multidimensional scaling plot of 276 genotyped Friesian horses calculated with cluster and mds-plot commands in PLINK software v1.07 [28, 29] using autosomal SNPs. (DOCX 31 kb
Additional file 4: of Copy number variations in Friesian horses and genetic risk factors for insect bite hypersensitivity
Regional association plot (ECA20) of insect bite hypersensitivity in Friesian horses. Significance level based on allele frequency differences between cases (n = 141) and controls (n = 135) using a χ2-test (1df). The horizontal red line is the Bonferroni corrected significance level (P-value = 1.63 × 10− 7). (DOCX 27 kb
Additional file 7: of Copy number variations in Friesian horses and genetic risk factors for insect bite hypersensitivity
5350 CNVRs detected by CNVRuler based on 15,041 CNVs identified by PennCNV in 222 Friesian horses. 5350 CNVRs detected by CNVRuler based on 15,041 CNVs identified in PennCNV [33–35] in 222 Friesian horses. Information that is presented includes CNVR identification (CNVR_ID), Equus caballus chromosome (ECA), start position (in bp), end position (in bp), size (in bp), copy number state, number of horses (N) with CNVR and whether the CNVR includes a gene(s) and is present in 1 horse (private) or more (shared). The gene(s) located within the CNVR were identified using human orthologues. Start and end position of the genes annotated in the horse genome are presented, including Ensembl IDs and whether the CNVR is upstream, inside, downstream of the gene or encompasses the gene. (XLSX 603 kb
Additional file 9: of Copy number variations in Friesian horses and genetic risk factors for insect bite hypersensitivity
Visualization of individual CNVs within the CNVRs with the lowest P-value in the association tests. Visualization of individual CNVs within the CNVR on ECA10:12,948,489-13,075,518 (association test including both gains and losses), ECA20:30,624,048-30,689,273 (association test including gains only) and ECA20:30,743,179-30,775,429 (association test including losses only). Each row represents one horse and the X-axis is the position on the chromosome. The black line marks the location of the CNVR. Blue lines represent controls, red lines cases. A dotted line represents a deletion (state = 0n), a striped line represents a CNV with state equals 1n and a solid line represents a duplication (3n). (DOCX 50 kb
Unadjusted and genome-wide <i>p</i>-values for the four GWA analyses performed.
<p>Unadjusted and genome-wide <i>p</i>-values for the four GWA analyses performed.</p
Manhattan plots for Chromosome 8 (ECA8).
<p><sup>a</sup>Manhattan plot based on the results of the cases and controls structured association analysis. <sup>b</sup>Manhattan plot based on the results of the cases and controls principal component analysis. <sup>c</sup>Manhattan plot based on the results of the principal component analysis of IBH severity. <sup>d</sup>Manhattan plot based on the results of the mixed model-structured association analysis of IBH severity. <sup>e</sup>The red line indicates the Bonferroni-corrected significance threshold; the black line indicates the threshold for suggestive SNPs (<i>P</i> < 1x10<sup>-5</sup>).</p
QQ plots for Chromosome 8 (ECA8).
<p><sup>a</sup>Corrected QQ plot for the cases and controls structured association analysis; uncorrected λ = 1.3659. <sup>b</sup>Corrected QQ plot for the cases and controls principal component analysis; uncorrected λ = 1.2599. <sup>c</sup>Corrected QQ plot for the principal component analysis of IBH severity; uncorrected λ = 1.2657. <sup>d</sup>Corrected QQ plot for the mixed model-structured association analysis of IBH severity; uncorrected λ = 1.0222.</p