Number (%) of waves with available hormone measurements for each hormone for females and males.

(PDF)</p

Scatterplots showing the relationship between age and (log-transformed) saliva hormone levels for females and males with hormone values above the detection limit.

To illustrate the longitudinal nature of the data, repeated measures over the follow-up period have been connected (black lines) for 10 randomly selected individuals.</p

Estimates of fixed-effect coefficients, with 95% confidence intervals, in the mixed-effects models.

Estimates of fixed-effect coefficients, with 95% confidence intervals, in the mixed-effects models.</p

Descriptive statistics for age at saliva collection, time of saliva collection, saliva flow rate, and hormone measurements at waves 1 to 4 for females (n = 667) and males (n = 572).

Descriptive statistics for age at saliva collection, time of saliva collection, saliva flow rate, and hormone measurements at waves 1 to 4 for females (n = 667) and males (n = 572).</p

Histogram of log detectable values for DHEA-S overlaid with a normal distribution curve.

(PDF)</p

Percentage of individuals who changed class after excluding hormone measurements not collected at school setting (n = 149).

(PDF)</p

Number (%) of females and males in classes based on hormone levels (L1: Low-level, L2: Mid-level, or L3: High-level compared to population) at age 9 years old and rate of progression during follow-up period (R1: Slow/normal rate, R2: Fast rate compared to population).

Number (%) of females and males in classes based on hormone levels (L1: Low-level, L2: Mid-level, or L3: High-level compared to population) at age 9 years old and rate of progression during follow-up period (R1: Slow/normal rate, R2: Fast rate compared to population).</p

Linear mixed-effect models for saliva hormones.

(PDF)</p

Estimates of standard deviation and correlation parameters in the mixed-effects models for adrenal hormone measured at age 9 years old.

Estimates of standard deviation and correlation parameters in the mixed-effects models for adrenal hormone measured at age 9 years old.</p

Percentage of individuals who changed class after excluding hormone measurements collected after 11am (n = 51).

(PDF)</p