18 research outputs found
Western blotting with antibodies specific for H3K4me3 and H3K9me3.
<p>was used to determine the degree of lysine-specific methylation, in relationship with Kdm5c/5d (H3K4me3 demethylase) and Kmt1a/1b (H3K9 trimethylases). No sex- or diet-specific signal was observed.</p
Ingenuity pathway analysis for gene responding to HFD: Biological functions in female.
a<p>The first 10 biological categories of function are indicated and function annotation with a significant z-score are detailed.</p>u<p>Upregulated genes. <sup>d</sup>Downregulated genes.</p><p>Underline corresponds to genes deregulated both in female and male placentas.</p
Ingenuity pathway analysis for sexually dimorphic genes: Biological functions under CD conditions.
a<p>The first 10 biological categories of function are indicated and function annotation with a significant z-score are detailed.</p>f<p>Genes more expressed in females. <sup>m</sup>Genes more expressed in males.</p><p>Underline corresponds to genes both dimorphic under CD or HFD conditions.</p
Ingenuity pathway analysis for sexually dimorphic genes: Networks under HFD conditions (M HFD vs F HFD).
a<p>Networks with scores ≥25 are indicated. <sup>b</sup>Genes in bold are included in our datasets.</p>f<p>Genes more expressed in females. <sup>m</sup>Genes more expressed in males.</p><p>Underline corresponds to genes both dimorphic under CD or HFD conditions.</p
Ingenuity pathway analysis for gene responding to HFD: Networks in female.
a<p>Networks with scores ≥25 are indicated. <sup>b</sup>Genes in bold are included in our datasets.</p>u<p>Upregulated genes. <sup>d</sup>Downregulated genes.</p><p>Underline corresponds to genes deregulated both in female and male placentas.</p
Ingenuity pathway analysis for sexually dimorphic genes: Biological functions under HFD conditions.
a<p>The first 10 biological categories of function are indicated and function annotation with a significant z-score are detailed.</p>f<p>Genes more expressed in females. <sup>m</sup>Genes more expressed in males.</p><p>Underline corresponds to genes both dimorphic under CD or HFD conditions.</p
Effect of sex and maternal diet on the epigenetic machinery enzyme gene expression.
<p>Log<sub>2</sub>(fold change) are indicated in brackets (microarrays/RT-qPCR). ND = not done. NS = non significant.</p
Venn diagram representing the number of genes in LIMMA statistical analysis.
<p>(A) displaying significant sexual dimorphism or (B) significantly dysregulated under the influence of maternal high-fat diet.</p
Ingenuity pathway analysis for gene responding to HFD: Biological functions in male.
a<p>The first 10 biological categories of function are indicated and function annotation with a significant z-score are detailed.</p>u<p>Upregulated genes. <sup>d</sup> Downregulated genes.</p><p>Underline corresponds to genes deregulated both in female and male placentas.</p
Ingenuity pathway analysis for gene responding to HFD: Networks in male.
a<p>Networks with scores ≥25 are indicated. <sup>b</sup>Genes in bold are included in our datasets.</p>u<p>Upregulated genes. <sup>d</sup>Downregulated genes.</p><p>Underline corresponds to genes deregulated both in female and male placentas.</p