A pilot study on the impact of occupational therapy home programming for young children with Cerebral Palsy

Occupational therapy home programs are a common approach used to provide interventions for children with cerebral palsy, but there is little evidence to demonstrate the effectiveness of such programs. This singlegroup pretest–posttest design pilot study evaluated the impact of an occupational therapy home program implemented with 20 children who had spastic hemiplegic cerebral palsy (ages 2–7 years, mean 3.8). We measured impact using Goal Attainment Scaling (GAS), the Pediatric Evaluation of Disability Inventory (PEDI), and the Quality of Upper Extremity Skills Test (QUEST). We measured participation amount through a parent self-report log. Significant changes following intervention occured in scores on the GAS, the PEDI Functional Skills and Caregiver Assistance Scales, and the QUEST, but has found no relationship between participation amount and outcome using the same measures. These promising results suggest that further investigation of the impact of occupational therapy home programs is warranted

Parent experience of implementing home programs: Semi-structured interviews

Abstract presented at the 5th Biennial Conference of the Australasian Academy of Cerebral Palsy & Developmental Medicine, 3-6 March 2010, Christchurch, New Zealan

Root‐derived trans‐zeatin cytokinin protects Arabidopsis plants against photoperiod stress

Recently, a novel type of abiotic stress caused by a prolongation of the light period - coined photoperiod stress - has been described in Arabidopsis. During the night after the prolongation of the light period, stress and cell death marker genes are induced. The next day, strongly stressed plants display a reduced photosynthetic efficiency and leaf cells eventually enter programmed cell death. The phytohormone cytokinin (CK) acts as a negative regulator of this photoperiod stress syndrome. In this study, we show that Arabidopsis wild‐type plants increase the CK concentration in response to photoperiod stress. Analysis of cytokinin synthesis and transport mutants revealed that root‐derived trans‐zeatin (tZ)‐type CKs protect against photoperiod stress. The CK signalling proteins ARABIDOPSIS HISTIDINE PHOSPHOTRANSFER PROTEIN 2 (AHP2), AHP3 and AHP5 and transcription factors ARABIDOPSIS RESPONSE REGULATOR 2 (ARR2), ARR10 and ARR12 are required for the protective activity of CK. Analysis of higher order B‐type arr mutants suggested that a complex regulatory circuit exists in which the loss of ARR10 or ARR12 can rescue the arr2 phenotype. Together the results revealed the role of root‐derived CK acting in the shoot through the two‐component signalling system to protect from the negative consequences of strong photoperiod stress

The Photoperiod Stress Response in Arabidopsis thaliana Depends on Auxin Acting as an Antagonist to the Protectant Cytokinin

Fluctuating environmental conditions trigger adaptive responses in plants, which are regulated by phytohormones. During photoperiod stress caused by a prolongation of the light period, cytokinin (CK) has a protective function. Auxin often acts as an antagonist of CK in developmental processes and stress responses. Here, we investigated the regulation of the photoperiod stress response in Arabidopsis thaliana by auxin and its interaction with CK. Transcriptome analysis revealed an altered transcript abundance of numerous auxin metabolism and signaling genes after photoperiod stress treatment. The changes appeared earlier and were stronger in the photoperiod-stress-sensitive CK receptor mutant arabidopsis histidine kinase 2 (ahk2),3 compared to wild-type plants. The concentrations of indole-3-acetic acid (IAA), IAA-Glc and IAA-Asp increased in both genotypes, but the increases were more pronounced in ahk2,3. Genetic analysis revealed that the gain-of-function YUCCA 1 (YUC1) mutant, yuc1D, displayed an increased photoperiod stress sensitivity. In contrast, a loss of the auxin receptors TRANSPORT-INHIBITOR-RESISTANT 1 (TIR1), AUXIN SIGNALING F-BOX 2 (AFB2) and AFB3 in wild-type and ahk2,3 background caused a reduced photoperiod stress response. Overall, this study revealed that auxin promotes response to photoperiod stress antagonizing the protective CK

Wavefront control in space with MEMS deformable mirrors for exoplanet direct imaging

To meet the high contrast requirement of 1×10[superscript −10] to image an Earth-like planet around a sun-like star, space telescopes equipped with coronagraphs require wavefront control systems. Deformable mirrors (DMs) are a key element of a wavefront control system, as they correct for imperfections, thermal distortions, and diffraction that would otherwise corrupt the wavefront and ruin the contrast. The goal of the CubeSat DM technology demonstration mission is to test the ability of a microelectromechanical system (MEMS) DM to perform wavefront control on-orbit on a nanosatellite platform. We consider two approaches for an MEMS DM technology demonstration payload that will fit within the mass, power, and volume constraints of a CubeSat: (1) a Michelson interferometer and (2) a Shack-Hartmann wavefront sensor. We clarify the constraints on the payload based on the resources required for supporting CubeSat subsystems drawn from subsystems that we have developed for a different CubeSat flight project. We discuss results from payload laboratory prototypes and their utility in defining mission requirements

The Iowa Homemaker vol.31, no.1

Finger or Fork, Doris Jean Coxon, page 3 Learn to Play, Floramae Gates, page 4 What’s Your Beef, Jackie Morrison, page 5 Born to Travel, Ruth Anderson, page 6 Hardships, Colene Ruch, page 7 The O’Bryan Touch, Nancy Voss, page 8 What’s New, Constance Cornwell, Harriet LaRue, page 10 Here’s An Idea, Darleen Bornschein, Jean McGhie, page 12 Alums in the News, Jane Novak, page 15 Trends, Anne Dallager, page 1

The Iowa Homemaker vol.30, no.8

Seniors Say, Harriet LaRue, page 3 Congratulations from the 1921 Staff, page 4 1921-1951, Mrs. Fred Ferguson, Mrs. Frank Kerekes, Mrs. Eloise Hauser, page 5 College Decision, Anne Ekdahl, page 6 Words From a Waiter, Alane Baird, page 7 9 Previews of Home Economics, Barbara Short, page 8 Godey’s Lady’s Book, Patricia Binder, page 11 Here’s An Idea, Carol Dee Legg, page 14 What’s New, Nancy Voss, page 16 Alums in the News, Jane Novak, page 18 Information, Please, Doris Cook, page 20 Trends, Nancy Butler, page 2

A Haploid Pseudo-Chromosome Genome Assembly for a Keystone Sagebrush Species of Western North American Rangelands

Increased ecological disturbances, species invasions, and climate change are creating severe conservation problems for several plant species that are widespread and foundational. Understanding the genetic diversity of these species and how it relates to adaptation to these stressors are necessary for guiding conservation and restoration efforts. This need is particularly acute for big sagebrush (Artemisia tridentata; Asteraceae), which was once the dominant shrub over 1,000,000 km2 in western North America but has since retracted by half and thus has become the target of one of the largest restoration seeding efforts globally. Here, we present the first reference-quality genome assembly for an ecologically important subspecies of big sagebrush (A. tridentata subsp. tridentata) based on short and long reads, as well as chromatin proximity ligation data analyzed using the HiRise pipeline. The final 4.2-Gb assembly consists of 5,492 scaffolds, with nine pseudo-chromosomal scaffolds (nine scaffolds comprising at least 90% of the assembled genome; n = 9). The assembly contains an estimated 43,377 genes based on ab initio gene discovery and transcriptional data analyzed using the MAKER pipeline, with 91.37% of BUSCOs being completely assembled. The final assembly was highly repetitive, with repeat elements comprising 77.99% of the genome, making the Artemisia tridentata subsp. tridentata genome one of the most highly repetitive plant genomes to be sequenced and assembled. This genome assembly advances studies on plant adaptation to drought and heat stress and provides a valuable tool for future genomic research

MEMS deformable mirror CubeSat testbed

To meet the high contrast requirement of 1 × 10[superscript −10] to image an Earth-like planet around a Sun-like star, space telescopes equipped with coronagraphs require wavefront control systems. Deformable mirrors are a key element of these systems that correct for optical imperfections, thermal distortions, and diffraction that would otherwise corrupt the wavefront and ruin the contrast. However, high-actuator-count MEMS deformable mirrors have yet to fly in space long enough to characterize their on-orbit performance and reduce risk by developing and operating their supporting systems. The goal of the MEMS Deformable Mirror CubeSat Testbed is to develop a CubeSat-scale demonstration of MEMS deformable mirror and wavefront sensing technology. In this paper, we consider two approaches for a MEMS deformable mirror technology demonstration payload that will fit within the mass, power, and volume constraints of a CubeSat: 1) a Michelson interferometer and 2) a Shack-Hartmann wavefront sensor. We clarify the constraints on the payload based on the resources required for supporting CubeSat subsystems drawn from subsystems that we have developed for a different CubeSat flight project. We discuss results from payload lab prototypes and their utility in defining mission requirements.United States. National Aeronautics and Space Administration (Office of the Chief Technologist NASA Space Technology Research Fellowship)Jeptha and Emily Wade FundMassachusetts Institute of Technology. Undergraduate Research Opportunities Progra