Post-restoration evaluation of urban streams in central Texas

This Working paper includes an image of Waller Creek at Shipe Park post-restoration. More relevant data/information will likely surface in the completed report.Waller Creek Working Grou

The role of family social, human and financial capital in family business sustainability - A Malaysian case study

This paper aims to explore the nature of family capital in the form of family social, human and financial capital in the family business. It looks at the contribution of these three forms of family capital as inputs into the business over the stages of the business life-cycle and how they operate to build and sustain the business in that time

Ultracold molecules: vehicles to scalable quantum information processing

We describe a novel scheme to implement scalable quantum information processing using Li-Cs molecular state to entangle $^{6}$Li and $^{133}$Cs ultracold atoms held in independent optical lattices. The $^{6}$Li atoms will act as quantum bits to store information, and $^{133}$Cs atoms will serve as messenger bits that aid in quantum gate operations and mediate entanglement between distant qubit atoms. Each atomic species is held in a separate optical lattice and the atoms can be overlapped by translating the lattices with respect to each other. When the messenger and qubit atoms are overlapped, targeted single spin operations and entangling operations can be performed by coupling the atomic states to a molecular state with radio-frequency pulses. By controlling the frequency and duration of the radio-frequency pulses, entanglement can either be created or swapped between a qubit messenger pair. We estimate operation fidelities for entangling two distant qubits and discuss scalability of this scheme and constraints on the optical lattice lasers

C. elegans Germ Cells Switch between Distinct Modes of Double-Strand Break Repair During Meiotic Prophase Progression

Chromosome inheritance during sexual reproduction relies on deliberate induction of double-strand DNA breaks (DSBs) and repair of a subset of these breaks as interhomolog crossovers (COs). Here we provide a direct demonstration, based on our analysis of rad-50 mutants, that the meiotic program in Caenorhabditis elegans involves both acquisition and loss of a specialized mode of double-strand break repair (DSBR). In premeiotic germ cells, RAD-50 is not required to load strand-exchange protein RAD-51 at sites of spontaneous or ionizing radiation (IR)-induced DSBs. A specialized meiotic DSBR mode is engaged at the onset of meiotic prophase, coincident with assembly of meiotic chromosome axis structures. This meiotic DSBR mode is characterized both by dependence on RAD-50 for rapid accumulation of RAD-51 at DSB sites and by competence for converting DSBs into interhomolog COs. At the mid-pachytene to late pachytene transition, germ cells undergo an abrupt release from the meiotic DSBR mode, characterized by reversion to RAD-50-independent loading of RAD-51 and loss of competence to convert DSBs into interhomolog COs. This transition in DSBR mode is dependent on MAP kinase-triggered prophase progression and coincides temporally with a major remodeling of chromosome architecture. We propose that at least two developmentally programmed switches in DSBR mode, likely conferred by changes in chromosome architecture, operate in the C. elegans germ line to allow formation of meiotic crossovers without jeopardizing genomic integrity. Our data further suggest that meiotic cohesin component REC-8 may play a role in limiting the activity of SPO-11 in generating meiotic DSBs and that RAD-50 may function in counteracting this inhibition

Biliary Cystadenoma Causing Obstructive Jaundice: Case Report and Literature Review

Biliary cystadenomas are rare, potentially malignant neoplasms of biliary origin. Presentation is usually with vague and non-specific symptoms. Here, we describe an unusual case of biliary cystadenoma in a woman presenting with acute onset obstructive jaundice and review the relevant literature of 26 such cases reported over the last two decades