Patient demographics, procedural data and outcomes.

<p>Patient demographics, procedural data and outcomes.</p

Clauss fibrinogen increase after weaning from CPB, according to surgery type.

<p>Clauss fibrinogen measurements over time, starting at the time point <i>Protomine</i>. The comprehensive plots show all patients, with the three types of surgery represented by different symbols. Predictions based on the fixed effects of the three respective linear mixed-effects models are superimposed.</p

Patient flow diagram.

<p>CABG = coronary artery bypass grafting; AVR = aortic valve replacement; AAR = ascending aorta replacement; HCA = hypothermic circulatory arrest. n indicates number of patients.</p

Patient- and CPB-related factors influencing clauss fibrinogen levels and FIBTEM-MCF at <i>Protamine</i>.

<p>Patient- and CPB-related factors influencing clauss fibrinogen levels and FIBTEM-MCF at <i>Protamine</i>.</p

Receiver operator characteristic curve analysis of blood parameters for death in the ICU.

<p>The value of the Area Under the Curve for each blood parameter and the 95% confidence intervals are listed on the bottom right of the figure. APACHE II = Acute Physiology and Chronic Health Evaluation II, IL = Interleukin, SOFA = Sequential Organ Failure Assessment.</p

Survival curves of patients with sepsis with or without shock.

<p>Using Kaplan-Meier curves, stratified by Gas6 measurement at admission with a cut-off value of 249% (relative to Gas6 concentration in normal plasma) (<i>P</i> = 0.026, Log-rank test).</p

Correlation between the plasma levels of Gas6 and those of other biomarkers.

<p>Correlation between the plasma levels of Gas6 and those of other biomarkers.</p

Performance of different biomarkers to predict mortality based on ROC curve area.

<p>Performance of different biomarkers to predict mortality based on ROC curve area.</p

Flow diagram of patients included in the study.

<p>Flow diagram of patients included in the study.</p

Evolution of Gas6 levels during ICU stay.

<p>The scheme is based on a linear mixed model without interaction between time in ICU and survival. Round represent the observed measures in survivors (a) and non-survivors (b), respectively. Lines represent the model-fitted values.</p