Post-procedural stroke after CAS and CEA.

<p>Random effects odds ratio and 95% confidence interval for the post-procedural incidence of stroke after CAS and CEA.</p

New DWI cerebral lesions after CAS and CEA.

<p>Random effects odds ratio and 95% confidence interval for the primary endpoint of new ischemic lesions at DWI after CAS and CEA.</p

Flow diagram.

<p>Studies included in the meta-analysis.</p

Characteristics of the studies included in the meta-analysis.

<p>*This number indicates the total number of CAS and CEA procedures performed in each study and for which the DWI is available.</p><p>**The reported characteristics refer to the overall population included in the original study and not to the 58 included in the meta-analysis because of DWI availability.</p><p>Abbreviations: CAD = coronary artery disease; CAS = carotid artery stenting; CEA = carotid endarterectomy; EPD = embolic protection device; ICSS-MRI = international carotid stenting study-magnetic resonance imaging; RCT = randomized clinical trial</p><p>Characteristics of the studies included in the meta-analysis.</p

Supplemental Material, Fig_S1 - ESOPE-Equivalent Pulsing Protocols for Calcium Electroporation: An <i>In Vitro</i> Optimization Study on 2 Cancer Cell Models

<p>Supplemental Material, Fig_S1 for ESOPE-Equivalent Pulsing Protocols for Calcium Electroporation: An <i>In Vitro</i> Optimization Study on 2 Cancer Cell Models by Stefania Romeo, Anna Sannino, Maria Rosaria Scarfì, P. Thomas Vernier, Ruggero Cadossi, Julie Gehl, and Olga Zeni in Technology in Cancer Research & Treatment</p

DNA migration pattern of Jurkat cells immediately after nsPEF exposure at 1.0, 1.5, 2.5 MV/m.

<p>For each pulse amplitude, 3 independent experiments were carried out; each data point represents the 75^th percentile of the distributions. * P<0.01 (one sided Kolmogorov-Smirnov test; sham <i>vs</i> exposed samples).</p

Time course of DNA migration pattern for 60 ns, 2.5 MV/m nsPEF exposed and sham-exposed Jurkat cells.

<p>Results are presented as 75^th percentile of the distributions.</p><p>*P<0.01 (one sided Kolmogorov-Smirnov test; sham <i>vs</i> exposed samples).</p

Jurkat cells plasma membrane was selectively permeabilized.

<p>Plasma membrane permeabilization of Jurkat cells after 1 pulse, 60 ns, 2.5 MV/m, presented as representative fluorescence histograms for A) YO-PRO-1 uptake immediately (0 min) and 120 min post pulse and B) PI uptake immediately, 120 min and 180 min post pulse. C) Molecular structures and 3-D models (van der Waal's radii) of the dyes.</p

Cell growth remained unaffected after pulse exposure.

<p>Jurkat cell growth after a single, 60 ns, 2.5 MV/m pulse. Mean ± SD of 7 independent experiments.</p

DNA migration pattern of Jurkat cells under nsPEFs <i>vs</i> MMS.

<p>Distribution of % DNA in the tail for Jurkat cells following nsPEF exposure (Exp), sham exposure (Sham) and 2 hr exposure to 10 µM of methyl methanesulfonate (MMS). Results refer to a representative experiment carried out at 1 pulse, 2.5 MV/m, 60 ns.</p