Multilevel multivariable random effects logistic regression analysis of factors associated with ocular <i>C. trachomatis</i> infection.

a<p>Adjusted Odds Ratio (aOR) using two-level multivariable mixed effects logistic regression modelling; CI = confidence interval.</p>b<p>p-value for Wald test (Wald's Chi²); significant associations (where <i>p≤0.05</i>) are highlighted in bold.</p>c<p>researcher observed.</p

The relationship between trachoma and presence of infection with <i>C. trachomatis</i> (<i>Ct</i>).

a<p>N = total number and % = proportion.</p>b<p>Using the WHO Simplified Grading System where TF = trachomatous inflammation-follicular, TI = trachomatous inflammation-intense, TS = trachomatous scarring <a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0002900#pntd.0002900-Thylefors1" target="_blank">[23]</a>. Individuals may appear in more than one clinical category.</p>c<p><i>Ct</i> DNA detected (<i>Ct</i>+) or absent (<i>Ct</i>−) by Amplicor PCR.</p

Multilevel univariable random effects logistic regression analysis of factors associated with active trachoma^a.

a<p>Active trachoma defined as TF (inflammatory trachoma-follicular) and/or TI (inflammatory trachoma-intense) using the WHO simplified scoring system <a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0002900#pntd.0002900-Thylefors1" target="_blank">[23]</a>.</p>b<p>Unadjusted (crude) Odds Ratio (cOR) from two-level univariable mixed effects logistic regression analyses; CI = confidence interval.</p>c<p>p-value for Wald test (Wald's Chi²); significant associations (where <i>p≤0.05</i>) are highlighted in bold.</p>d<p>Continuous numeric variables.</p>e<p>reported by household head.</p>f<p>a ‘vasilha’ is a vessel of capacity ∼30 litres.</p>g<p>researcher observed.</p>h<p>researcher observed within 15 m of the household.</p

Multilevel univariable random effects logistic regression analysis of factors associated with ocular <i>C. trachomatis</i> infection.

a<p>Unadjusted (crude) Odds Ratio (cOR) using two-level univariable mixed effects logistic regression; CI = confidence interval.</p>b<p>p-value for Wald test (Wald's Chi²); significant associations (where <i>p≤0.05</i>) are highlighted in bold.</p>c<p>Continuous numeric variables.</p>d<p>reported by household head.</p>e<p>a ‘vasilha’ is a vessel of capacity ∼30 litres.</p>f<p>researcher observed.</p>g<p>researcher observed within 15 m of the household.</p

Multilevel multivariable random effects logistic regression analysis of factors independently associated with active trachoma^a.

a<p>Active trachoma defined as TF (inflammatory trachoma-follicular) and/or TI (inflammatory trachoma-intense) using the WHO simplified scoring system <a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0002900#pntd.0002900-Thylefors1" target="_blank">[23]</a>.</p>b<p>Model 1 shows the association of predictor variables with active trachoma.</p>c<p>Model 2 includes the presence of <i>C. trachomatis</i> infection and demonstrates the effect of its inclusion on the predictor variables. Some of the association in Model 1 is mediated by <i>C. trachomatis</i> infection.</p>d<p>Adjusted Odds Ratio (aOR) using multivariable two-level mixed effects logistic regression modelling; CI = confidence interval.</p>e<p>p-value for Wald test (Wald's Chi²); significant associations (where <i>p≤0.05</i>) are highlighted in bold.</p

Study population characteristics.

a<p>Total rural population on Bubaque, Canhabaque, Soga and Rubane <a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0002900#pntd.0002900-National1" target="_blank">[4]</a>.</p>b<p>N = total number and % = proportion. IQR = Interquartile range.</p