Built environment, creativity, social art: the recovery of public space as engine of human development

The paper is a part of a comprehensive research aimed at operationalizing HUL approach and experimenting it in the buffer zone of Pompei, mainly in Torre Annunziata (Italy), and is based on the recognition of art and cultural heritage as tools for "managing the change" of landscape. The proposed thesis is that the recovery of public space, configured by art and culture and shared with local community according to an inclusive approach, contribute to regenerate creativity, reconstructing the relationships between people, communities and landscape. This lays the foundations for a "creative environment" and regenerative, concived as a prerequisite of development. In this process, art is a driver which acts on the creativity of local residents, stimulating their critical thinking, open-mindedness and design capacity, and leading them to accept diversity as an opportunity. Focusing on theories and on the empirical analysis of a best practice, MAAM Museum in Rome, this paper has three main objectives: to produce empirical evidence on the cause/effect relationship between art, heritage and community relationships; to make transferable and replicable in other contexts, such as Torre Annunziata, the process experienced at MAAM; to develop a methodology able to soliciting, integrating and supporting the regeneration of relationships in the town of Torre Annunziata

Ambiente costruito, creatività, arte sociale. Il recupero dello spazio pubblico nell’approccio del paesaggio storico urbano

La ricerca si colloca nel quadro degli studi volti a rendere operativo l’approccio del paesaggio storico urbano attraverso strumenti per la “gestione del cambiamento” del paesaggio. Riconoscendo la “piazza” come il luogo in cui si concentrano i valori urbani e si sublima l'idea stessa di comunità, la ricerca affronta il tema del recupero dello spazio pubblico come azione strategica per promuovere uno sviluppo umano sostenibile a partire da azioni locali. La tesi proposta è che il recupero dello spazio pubblico, configurato dall’arte e dalla cultura e condiviso con le comunità locali in un processo inclusivo, contribuisce a rigenerare la creatività, ricostruendo le relazioni tra gli individui, la comunità ed il paesaggio e gettando le basi per la costruzione di un «ambiente creativo», in cui le relazioni diventano sinergie creative e produttive. La tesi viene dimostrata attraverso lo studio teorico, l'analisi di un caso studio e supportata dalla sperimentazione di un living lab nel Parco Nazionale del Cilento, Vallo di Diano e Alburni

Artists Residencies, Challenges and Opportunities for Communities’ Empowerment and Heritage Regeneration

The paper debates the results of a research carried out by the Department of Architecture of the University of Naples “Federico II” (DiARC), as part of the Creative Europe 2018 Artists in Architecture, Re-activating modern European houses program (entitled EACEA 32/2017 and EACEA 35/2017; scientific coordinator: Maria Rita Pinto; project manager: Serena Viola). The research investigates the relationships between creativity and sharing as tools of a new form of social sustainability. These elements can induce positive effects on the settlement qualities of the places, acting as engines of the custody of the settlement values and the collaborative regeneration of the built environment. The methodology is based on participatory approaches able to restore the levels of cohesion, care, and creativity that the experimentation typology of the Artists Residencies is able to trigger on the territory and on the communities who inhabit it. The results return in the form of the complex process of the artist exhibition reception a significant strategy of sustainable development, capable of influencing the community by entrusting it with the role of custodian of the existing heritage and of renewing local entrepreneurship with innovative productions

Towards operationalizing UNESCO Recommendations on “Historic Urban Landscape”: a position paper

<p>This position paper critically analyses the process to implement the UNESCO Recommendation on the Historic Urban Landscape (2011), exploring evaluation tools, innovative business / management models and financing tools for the conservation and regeneration of Historic Urban Landscape (HUL), to make it operational in the perspective of a circular economy model of sustainable development for city / territory system regeneration. Through evaluation tools, it is possible to pass from general principles to operational practices; to produce empirical evidence of the economic, social and environmental benefits of HUL integrated conservation and regeneration. The challenge of generating a symbiosis between conservation and transformation issues requires adequate evaluation methods, business, management and financing tools, engaging civil society and local stakeholders, capturing both HUL tangible and intangible values to turn the historic urban landscape into a driver of sustainable growth. The analysis carried out in this paper shows that through the suggested tools it is possible to make operational the UNESCO Recommendations, transforming conflicts into opportunities, producing economic attractiveness and strengthen social awareness and cohesion.</p

Post-intervention Status in Patients With Refractory Myasthenia Gravis Treated With Eculizumab During REGAIN and Its Open-Label Extension

OBJECTIVE: To evaluate whether eculizumab helps patients with anti-acetylcholine receptor-positive (AChR+) refractory generalized myasthenia gravis (gMG) achieve the Myasthenia Gravis Foundation of America (MGFA) post-intervention status of minimal manifestations (MM), we assessed patients' status throughout REGAIN (Safety and Efficacy of Eculizumab in AChR+ Refractory Generalized Myasthenia Gravis) and its open-label extension. METHODS: Patients who completed the REGAIN randomized controlled trial and continued into the open-label extension were included in this tertiary endpoint analysis. Patients were assessed for the MGFA post-intervention status of improved, unchanged, worse, MM, and pharmacologic remission at defined time points during REGAIN and through week 130 of the open-label study. RESULTS: A total of 117 patients completed REGAIN and continued into the open-label study (eculizumab/eculizumab: 56; placebo/eculizumab: 61). At week 26 of REGAIN, more eculizumab-treated patients than placebo-treated patients achieved a status of improved (60.7% vs 41.7%) or MM (25.0% vs 13.3%; common OR: 2.3; 95% CI: 1.1-4.5). After 130 weeks of eculizumab treatment, 88.0% of patients achieved improved status and 57.3% of patients achieved MM status. The safety profile of eculizumab was consistent with its known profile and no new safety signals were detected. CONCLUSION: Eculizumab led to rapid and sustained achievement of MM in patients with AChR+ refractory gMG. These findings support the use of eculizumab in this previously difficult-to-treat patient population. CLINICALTRIALSGOV IDENTIFIER: REGAIN, NCT01997229; REGAIN open-label extension, NCT02301624. CLASSIFICATION OF EVIDENCE: This study provides Class II evidence that, after 26 weeks of eculizumab treatment, 25.0% of adults with AChR+ refractory gMG achieved MM, compared with 13.3% who received placebo

Minimal Symptom Expression' in Patients With Acetylcholine Receptor Antibody-Positive Refractory Generalized Myasthenia Gravis Treated With Eculizumab

The efficacy and tolerability of eculizumab were assessed in REGAIN, a 26-week, phase 3, randomized, double-blind, placebo-controlled study in anti-acetylcholine receptor antibody-positive (AChR+) refractory generalized myasthenia gravis (gMG), and its open-label extension

Caustic burn caused by intradermal self administration of muriatic acid for suicidal attempt: optimal wound healing and functional recovery with a non surgical treatment

Background. Caustic burns are burns of third and fourth degree caused by strong acids or strong bases. Muriatic acid is often used for suicidal attempt by ingestion. We describe a case of a caustic skin lesion caused by intravenous failed attempt of suicide by injection of Muriatic acid in a woman affected with bipolar-syndrome. Generally, caustic burns are treated by cleansing, escarectomy and coverage with skin grafts. Case report. We treated the patient with a non invasive technique with collagenase and hyaluronic acid sodium salt cream (Bionect start®), hyaluronic acid-based matrix (Hyalomatrix®) and Vacuum-Assisted Closure (VAC) Therapy®. Results. We obtained complete healing in 6 weeks. Conclusions. Combined use of non invasive techniques seems to ensure only advantages for both the patients and the Health System. It reduces health care costs and risks for the patients such as nosocomial infections. Patient’s compliance is high, as its quality of life. Complete healing of the wound is fast and recovery of function is full

Minimally Invasive Reconstructive Surgery for Complex Oncologic Foot Defects in Children

[No abstract available

A participatory approach for built heritage preservation. Case study: the Municipality of Sassano, Italy

In the contemporary scenario of turbulent cultural and societal change, the preservation of historic urban landscape authenticity introduces an approach based on values acknowledgement and adoption (Unesco, 2011). Within the Programme FARO (Financing for Starting Searches Originals 2012-2014) and the Project Cilento LabScape, the RRM lab, University of Naples Federico II, worked on research activities aimed at testing, for the National Park of Cilento and Vallo di Diano (Southern Italy), an integrated model capable of filling the gap between places and end users. A Living Lab focused on the shared management of the transformation occurring in buildings' elements and units of the landscape. The paper describes the experimental activity for Sassano Municipality. Rethinking management procedures and priorities, is one answer to prevent the consequences of identity loss. Working in a design perspective on the dynamics of interactions between people and places, has a big impact on the vulnerability of settlements