Model (iv): estimated covariate effects for age, BMI, HDL, and LDL.

<p>The solid line is the estimate. The dash-dotted lines are the point-wise 95% confidence intervals. The y-axis is the value of the function.</p

Histogram of log(1+CAC).

<p>Histogram of log(1+CAC).</p

Model (i.1): estimated covariate effects for age, BMI, HDL, and LDL.

<p>The solid line is the estimate. The dash-dotted lines are the point-wise 95% confidence intervals. The y-axis is the value of the function.</p

Model (ii.1): estimated covariate effects for age, BMI, HDL, and LDL.

<p>The solid line is the estimate. The dash-dotted lines are the point-wise 95% confidence intervals. The y-axis is the value of the function.</p

Model (ii.2): estimated covariate effects for age, BMI, HDL, and LDL.

<p>The solid line is the estimate. The dash-dotted lines are the point-wise 95% confidence intervals. The y-axis is the value of the function.</p

Estimated regression coefficients (standard errors) for covariates with parametric effects in all models.

<p>Estimated regression coefficients (standard errors) for covariates with parametric effects in all models.</p

Model (i.2): estimated covariate effects for age, BMI, HDL, and LDL.

<p>The solid line is the estimate. The dash-dotted lines are the point-wise 95% confidence intervals. The y-axis is the value of the function.</p

Primers used for mutant construction, complementation and RT-PCR analyses.

<p>Primers used for mutant construction, complementation and RT-PCR analyses.</p

Confocal scanning laser microscopy images of <i>Geobacter sulfurreducens</i> grown with different electron acceptors.

<p>Confocal scanning laser microscopy images of current harvesting and fumarate control biofilms of wild type <i>G. sulfurreducens.</i> Metabolically active (green) and inactive (red) cells where differentiated with a LIVE/DEAD kit based on the permeability of the cell membrane. A. 3-D projection, top view, fumarate control biofilm; B. slices through biofilm parallel to electrode large panel and perpendicular to electrode top and side panel, fumarate control biofilm; C. 3-D projection, top view, current harvesting biofilm; D. slices through biofilm parallel to electrode large panel and perpendicular to electrode top and side panel, current harvesting biofilm.</p

OmcZ sequence and identification.

<p>A. Amino acid sequence of OmcZ. The predicted cleavage site for mature OmcZ indicated by arrow. Confirmed heme-binding domains (CXXCH) are enclosed in boxes. OmcZ has 473 amino acid residues and 7 heme binding domains. B. Cytochrome content of loosely bound outer membrane protein-enriched fractions from fumarate and current-harvesting biofilms. Proteins (10 µg/lane) were separated by 12% Tris-Tricine denaturing polyacryamide gel electrophoresis and stained for heme. C. Peptides detected from two different sizes of OmcZs, fragments detected in the 50 KDa OmcZ are indicated in panel A in red; fragments detected in the 30 KDa OmcZ are indicated in panel A in green and fragments detected in both size OmcZ are indicated in blue.</p