Psoriasis risk conferred by the three MHC loci in the GAIN dataset.

a<p>‘+’ denotes genotype CT/TT (presence of the risk allele T);</p>b<p>‘+’ denotes genotype AA (absence of the protective allele G).</p

Comparison of the imputed <i>HLA-C</i> genotypes with true genotypes.

<p>Comparison of the imputed <i>HLA-C</i> genotypes with true genotypes.</p

Association of MHC SNPs with psoriasis.

<p>(A) Trend test of MHC SNPs in the GAIN dataset; (B) Logistic regression adjusted for <i>HLA-Cw*0602</i> in the GAIN dataset; (C) Logistic regression adjusted for <i>HLA-Cw*0602</i> and rs2073048 in the GAIN dataset. (D) Logistic regression adjusted for <i>HLA-Cw*0602</i> in the Chinese dataset; (E) Logistic regression adjusted for <i>HLA-Cw*0602</i> and rs28732201 in the Chinese dataset. The red lines indicate the significance level by Bonferroni correction for the number of SNPs tested. The numbers of SNPs are 1593, 1593, 1591, 226, and 252 for (A–E), respectively.</p