Attitude and level of COVID-19 vaccination and its determinants among patients with chronic disease visiting Debre Tabor Comprehensive Specialized Hospital, Northwest Ethiopia: A cross-sectional study.

IntroductionCoronavirus disease is a fatal viral disease caused by severe acute respiratory syndrome coronavirus 2. This study was aimed to assess the attitude, level of COVID-19 vaccine uptake, and its determinants among patients with chronic diseases visiting Debre Tabor Comprehensive Specialized Hospital, Northwest Ethiopia.MethodsAn institutional-based cross-sectional study was conducted among 422 randomly selected patients with chronic disease visiting Debre Tabor Comprehensive Specialized Hospital from February 1 to March 30, 2022. Bivariable and multivariable binary logistic regression analyses were done to identify associations between dependent and independent variables.ResultsAmong all participants, only 29.6% of patients were vaccinated with any of the COVID-19 vaccines at least one dose. Age from 31 to 40 years (AOR = 6.26, 95% CI: 2.69-14.56), attended collage and above (AOR = 6.3, 95% CI: 1.37, 28.68), positive attitude towards COVID-19 vaccine (AOR = 9.07, 95% CI: 4.51-18.22), good knowledge (AOR = 7.63, 95% CI: 1.08-16.85), history of COVID-19 (AOR = 4.33, 95% CI: 1.85-10.17), family history of COVID-19 (AOR = 3.99, 95% CI = 1.89-8.48), ever been tested for COVID-19 (AOR = 0.33, 95% CI: 0.15-0.74) were determinant factors for COVID-19 vaccine uptake.ConclusionCOVID-19 vaccine uptake among patients with chronic disease was very low. The main reasons for not being vaccinated were doubts about vaccine efficacy, the vaccine may cause disease by itself, and fear of adverse effects. Therefore, different stakeholders should enforce vaccine uptake and awareness creation

Attitude and level of COVID-19 vaccination and its determinants among patients with chronic disease visiting Debre Tabor Comprehensive Specialized Hospital, Northwest Ethiopia: A cross-sectional study

Introduction Coronavirus disease is a fatal viral disease caused by severe acute respiratory syndrome coronavirus 2. This study was aimed to assess the attitude, level of COVID-19 vaccine uptake, and its determinants among patients with chronic diseases visiting Debre Tabor Comprehensive Specialized Hospital, Northwest Ethiopia. Methods An institutional-based cross-sectional study was conducted among 422 randomly selected patients with chronic disease visiting Debre Tabor Comprehensive Specialized Hospital from February 1 to March 30, 2022. Bivariable and multivariable binary logistic regression analyses were done to identify associations between dependent and independent variables. Results Among all participants, only 29.6% of patients were vaccinated with any of the COVID-19 vaccines at least one dose. Age from 31 to 40 years (AOR = 6.26, 95% CI: 2.69–14.56), attended collage and above (AOR = 6.3, 95% CI: 1.37, 28.68), positive attitude towards COVID-19 vaccine (AOR = 9.07, 95% CI: 4.51–18.22), good knowledge (AOR = 7.63, 95% CI: 1.08–16.85), history of COVID-19 (AOR = 4.33, 95% CI: 1.85–10.17), family history of COVID-19 (AOR = 3.99, 95% CI = 1.89–8.48), ever been tested for COVID-19 (AOR = 0.33, 95% CI: 0.15–0.74) were determinant factors for COVID-19 vaccine uptake. Conclusion COVID-19 vaccine uptake among patients with chronic disease was very low. The main reasons for not being vaccinated were doubts about vaccine efficacy, the vaccine may cause disease by itself, and fear of adverse effects. Therefore, different stakeholders should enforce vaccine uptake and awareness creation

Incidence and predictors of early posttraumatic seizures among patients with moderate or severe traumatic brain injury in Northwest Ethiopia: an institution-based prospective study

Abstract Background Early posttraumatic seizure (PTS) is a well-known complication of traumatic brain injury (TBI) that can induce the development of secondary brain injuries, including increased intracranial pressure, brain death, and metabolic crisis which may result in worse outcomes. It is also a well-recognized risk factor for the development of late post-traumatic seizure and epilepsy. This study was aimed to assess the incidence and predictors of PTS among patients with moderate or severe TBI admitted to Debre Tabor Comprehensive Specialized Hospital, Northwest Ethiopia. Methods and setting An institutional-based prospective follow-up study was conducted on 402 patients with TBI admitted to the neurologic unit from June 1, 2022 to January 30, 2023. A systematic sampling technique was employed. The incidence rate of occurrence of early PTS was calculated. Both bivariable and multivariable Cox proportional hazard regression was performed. The strength of the association was measured using adjusted hazard ratios with a 95% confidence interval and p-values < 0.05. Results The incidence rate of early PTS was 2.7 per 100 person-days observation. Early PTS was observed in 17.7% of TBI patients. Age 75 and above (AHR = 2.85, 95%CI: 1.58–5.39), severe TBI (AHR = 2.06, 95%CI: 1.03–3.71), epidural hematoma (AHR = 2.4, 95% CI: 1.28–4.57), brain contusion (AHR = 2.6, 95%CI: 1.07–4.09), surgical intervention (AHR = 1.7, 95%CI: 1.03–3.82), posttraumatic amnesia (AHR = 1.99, 95%CI: 1.08–3.48), history of comorbidities (AHR = 1.56, 95%CI: 1.08–3.86), and history of alcohol abuse (AHR = 3.1, 95%CI: 1.89–5.23) were potential predictors of early PTS. Conclusion The incidence of early PTS was high. Since, early PTS can worsen secondary brain damage, knowing the predictors helps to provide an effective management plan for patients likely to develop early PTS and improve their outcome

Attitude towards COVID-19 vaccine among patients with chronic disease visiting in Debre Tabor Comprehensive Specialized Hospital, Northwest Ethiopia, 2022.

Attitude towards COVID-19 vaccine among patients with chronic disease visiting in Debre Tabor Comprehensive Specialized Hospital, Northwest Ethiopia, 2022.</p

Determinant factors of COVID-19 vaccine uptake among patients with chronic disease visiting Debre Tabor Comprehensive Specialized Hospital, Northwest Ethiopia, 2022.

Determinant factors of COVID-19 vaccine uptake among patients with chronic disease visiting Debre Tabor Comprehensive Specialized Hospital, Northwest Ethiopia, 2022.</p

Health status-related characteristics of patients with chronic disease visiting Debre Tabor Comprehensive Specialized Hospital, Northwest Ethiopia, 2022.

Health status-related characteristics of patients with chronic disease visiting Debre Tabor Comprehensive Specialized Hospital, Northwest Ethiopia, 2022.</p

Respondents’ main reason for not being vaccinated in patients with chronic disease, 2022.

Respondents’ main reason for not being vaccinated in patients with chronic disease, 2022.</p

Socio-demographic characteristics of patients with chronic disease visiting Debre Tabor Comprehensive Specialized Hospital, Northwest Ethiopia, 2022.

Socio-demographic characteristics of patients with chronic disease visiting Debre Tabor Comprehensive Specialized Hospital, Northwest Ethiopia, 2022.</p

Knowledge towards COVID-19 vaccine among patients with chronic disease visiting Debre Tabor Comprehensive Specialized Hospital, Northwest Ethiopia, 2022.

Knowledge towards COVID-19 vaccine among patients with chronic disease visiting Debre Tabor Comprehensive Specialized Hospital, Northwest Ethiopia, 2022.</p

Incidence, time to occurrence and predictors of peripheral intravenous cannula-related complications among neonates and infants in Northwest Ethiopia: an institutional-based prospective study

Abstract Background Peripheral intravenous cannulas (PIVC) are venous access devices commonly used for the administration of intravenous fluids, drugs, blood products, and parenteral nutrition. Despite its frequent use, it has complications that can seriously threaten patient safety, prolong hospital stays, and increases medical care costs. PIVC complications are associated with increased morbidity and reinsertion attempts are painful and anxiety-provoking for children and their parents. Therefore, this study was aimed to assess the incidence, time to occurrence and identify predictors for PIVC complications among infants admitted to Debre Tabor Comprehensive Specialized Hospital (DTCSH), Northwest Ethiopia. Methods and setting An institutional-based prospective cohort study was conducted on 358 infants admitted to a neonatal intensive care unit and pediatric ward, DTCSH from January 1 to April 30, 2022. A systematic sampling technique was employed. Results The incidence rate of PIVC complication was 11.6 per 1000 person-hours observation. PIVC complication was observed in 56.4% (202) of PIVCs, of which infiltration (42.1%) was the most common complication followed by phlebitis (29.7%). The median time to complication was 46 h. Anatomical insertion site (AHR = 2.85, 95%CI: 1.63–6.27), admission unit (AHR = 1.88, 95%CI: 1.07–4.02), sickness (AHR = 0.24, 95% CI: 1.31–4.66), medication type (AHR = 2.04, 95%CI: 1.13–3.66), blood transfusion (AHR = 0.79, 95%CI: 0.02–0.99), clinical experience (AHR = 0.52, CI:0.26–0.84), and flushing (AHR = 0.71, 95%CI: 0.34–0.98) were potential predictors of PIVC complication. Conclusion Knowing the predictor factors helps clinicians to provide effective care and to detect complications early