5,463 research outputs found
The Minorities and their Voices: A Critical Study of the Contemporary Indian English Writing with rererence to the Novels of Salman Rushdie, Rohinton Mistry, I. Allan Sealy and Esther David
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Adversarially Trained Autoencoders for Parallel-Data-Free Voice Conversion
We present a method for converting the voices between a set of speakers. Our
method is based on training multiple autoencoder paths, where there is a single
speaker-independent encoder and multiple speaker-dependent decoders. The
autoencoders are trained with an addition of an adversarial loss which is
provided by an auxiliary classifier in order to guide the output of the encoder
to be speaker independent. The training of the model is unsupervised in the
sense that it does not require collecting the same utterances from the speakers
nor does it require time aligning over phonemes. Due to the use of a single
encoder, our method can generalize to converting the voice of out-of-training
speakers to speakers in the training dataset. We present subjective tests
corroborating the performance of our method
A randomized prospective comparative study of efficacy of asenapine, iloperidone and zotepine in patients with psychosis
Background: Antipsychotic drugs constitute the mainstay in the treatment of schizophrenia and other psychotic disorders. For these medications to be maximally beneficial, they must be efficacious, with an acceptable side effect profile and be taken as prescribed. The objective of the study was to compare the efficacy of iloperidone, asenapine and zotepinein subjects with psychotic disorders.Methods: Randomized prospective study was conducted in the Department of Psychiatry of a tertiary care hospital, at Mysore, India. Sixty Patients who met the criteria for acute psychosis and schizophrenia according to ICD 10 were recruited. Atypical antipsychotics-asenapine, iloperidone and zotepine were administered and their efficacy was monitored by brief psychiatric rating scale (BPRS), which was administered on day one, week 1, week 3 and week 6.Results: Out of 60 recruited subjects 31 (51.7%) completed all four visits of the study. Iloperidone and asenapine showed significant improvement in efficacy than zotepine at week 6. Among the total dropouts 55.2% subjects didn’t come for follow-up and 44.8% were dropped due to development of side effects.Conclusions: In patients with acute psychosis and schizophrenia, iloperidone appears more effective and tolerated than the other two. Asenapine was effective but less tolerated and zotepine was less efficacious and produced poor response. Asenapine and zotepine have more dropouts and showed few uncommon extrapyramidal side effects
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