Empirical study of the mental representation of the image of the city (on the example of Kazan and Naberezhnye Chelny)

The purpose of the study is to identify the formed image of the territory in the perception of its inhabitants, using empirical research data for this. The main results of the study are that a comprehensive analysis of the mental representation of the urban space was carried out, on the basis of which the key elements of the image of the territory, the boundaries of the vernacular districts of the city, their urbanonymy were identified, as well as the significant role of urban open public spaces in the formation of the image of the territory. The authors come to the conclusion about the peculiarities of building images of cities, centered on symbolically significant elements and spaces that act as anchors for forming the image of a city in the perception of residents, attaching the population to the territory and constructing local identity

Empirical study of the mental representation of the image of the city (on the example of Kazan and Naberezhnye Chelny)

The purpose of the study is to identify the formed image of the territory in the perception of its inhabitants, using empirical research data for this. The main results of the study are that a comprehensive analysis of the mental representation of the urban space was carried out, on the basis of which the key elements of the image of the territory, the boundaries of the vernacular districts of the city, their urbanonymy were identified, as well as the significant role of urban open public spaces in the formation of the image of the territory. The authors come to the conclusion about the peculiarities of building images of cities, centered on symbolically significant elements and spaces that act as anchors for forming the image of a city in the perception of residents, attaching the population to the territory and constructing local identity

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field