Preterm Birth Prevention Post-Conization: A Model of Cervical Length Screening with Targeted Cerclage - Fig 2

<p><b>Mean difference in CL (mean % Δ CL) between time-points A: 13+0–15+6 weeks, B: 16+0–18+6 weeks, C: 20+0–22+6 weeks (A-B, B-C, and A-C) according to delivery outcome and cerclage insertion.</b> In women receiving a cerclage, mean CL started above 25mm at timepoint A, and went on to shorten, most significantly at timepoint C. The greatest difference in CL is observed between timepoints B-C and A-C in those that received a cerclage and went on to deliver preterm <37weeks, followed by term delivery with a cerclage. (<i>% ΔCL = percentage change in CL (mm) between screening time points; PTB = preterm birth <37 weeks; Screening time points = A</i>: <i>13+0–15+6 weeks</i>, <i>B</i>: <i>16+0–18+6 weeks</i>, <i>C</i>: <i>20+0–22+6 weeks; SD = standard deviation; Term = birth >37 weeks; W = weeks)</i>.</p

Sensitivity, specificity, likelihood ratios, and positive and negative predictive values for cerclage intervention and/or preterm birth <37 weeks, for screening time-points A, B and C, and percentage difference in CL between screening time-points A, B and C.

<p>Sensitivity, specificity, likelihood ratios, and positive and negative predictive values for cerclage intervention and/or preterm birth <37 weeks, for screening time-points A, B and C, and percentage difference in CL between screening time-points A, B and C.</p

Patient characteristics for women that delivered at term without cerclage (Group 1) and women that had cerclage or delivered prematurely (Group 2).

<p>Patient characteristics for women that delivered at term without cerclage (Group 1) and women that had cerclage or delivered prematurely (Group 2).</p

Preterm birth rates: A in the UK; B in the local population (three study units); C estimated in women post-cervical treatment based on UK rates; D in this study cohort.

<p>Preterm birth rates: A in the UK; B in the local population (three study units); C estimated in women post-cervical treatment based on UK rates; D in this study cohort.</p

Mean CL (mm)(SD) at screening time-points A, B, C and mean percentage ΔCL (SD) between screening time-points A-B, B-C, and A-C for Group 1 and 2.

<p>Mean CL (mm)(SD) at screening time-points A, B, C and mean percentage ΔCL (SD) between screening time-points A-B, B-C, and A-C for Group 1 and 2.</p