Regional association plot of the 1q24.1 risk locus.

<p>The figure shows −log₁₀<i>P</i> values (y-axis) versus chromosomal positions (x-axis; NCBI build 37). Genotyped SNPs are shown as triangles, with imputed SNPs as circles. rs3845536 has been highlighted through the use of a larger symbol. Colour intensity is proportional to LD with rs3845536: from white (<i>r</i>² = 0) to red (<i>r</i>² = 1.0). The light blue line indicates genetic recombination rates (estimated from 1000 Genomes Phase 1 CEU data). Nearby genes and transcripts are also shown.</p