Description of the specimens studied and heat map presentation of the ratio values of gene expression in tumor vs. adjacent tissues without histological pathology.

<p>SCC, squamous cell lung carcinoma; AdC, adenocarcinoma; AdC/SCC, both AdC and SCC cells were found in the tumor tissue; SCLC, small cell lung carcinoma; P, peripheral tumor location; C, central tumor location; Y, tumor with keratinization; N, tumor without keratinization; ‘-’, no data. The heat map is shown in log₂ scale. Gray cells indicate specimens with undetectable mRNA in both tumor and normal tissues.</p

Clustering of PC genes' expression data.

<p>Specimens numbering corresponds to <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0055752#pone-0055752-g001" target="_blank">Fig. 1</a>. The Ratio^T/N values in the heat map were row-normalized and shown in linear scale. Gray cells indicate specimens with undetectable mRNA in both normal and cancer tissues. Branch length reflects the distance between the dendrogram nodes. The clusters found are marked as C1, C2, C3 and C4.</p

Gene designations and TaqMan Gene Expression Assays used in real-time PCR.

*<p>HGNC – HUGO Gene Nomenclature Committee (<a href="http://www.genenames.org" target="_blank">www.genenames.org</a>).</p

Correlations between expression profiles of the genes studied.

*<p>R_s is Spearman correlation coefficient (p<0.05).</p