Additional file 1: of Development of a core outcome set for use in determining the overall success of gastroschisis treatment

Spirit Checklist. This file contains the completed SPIRIT checklist describing where key portions of text can be identified in the protocol. (DOC 121 kb

Summary of AMSTAR scores by guideline.

<p>Summary of AMSTAR scores by guideline.</p

Systematic reviews used across guidelines.

<p>Systematic reviews used across guidelines.</p

Scatterplot of AMSTAR and PRISMA scores.

<p>Scatterplot of AMSTAR and PRISMA scores.</p

PRISMA flow diagram of excluded studies.

<p>PRISMA flow diagram of excluded studies.</p

Summary of PRISMA scores by guidelines.

<p>Summary of PRISMA scores by guidelines.</p

PRISMA and AMSTAR scores and use of SRs across guidelines.

<p>PRISMA and AMSTAR scores and use of SRs across guidelines.</p

Guideline characteristics.

<p>Guideline characteristics.</p

The insect nymph <i>Anebos phrixos</i> gen. et sp. nov. MNHN.F.SOT005630 from the Montceau-les-Mines Lagerstätte, France.

<p>A. Dorsal view, showing wingpads. B. Lateral aspect, of note is the orientation of the head and limbs. C. Ventral abdomen demonstrating trilobite underside. D. Anterior view, showing head, antennae and possible maxillary palps, in addition to leg segmentation. Abbreviations: an = antenna; ca = central axis; ce = cerci; e = eye; fe = femur; L1–3 = legs 1–3; lz = lateral zone; mp = maxillary palps (?); ms = mesonotum; mt = metanotum; pn = pronotum; ta = tarsus; ti = tibia; wp = wing pad. All scale bars equal 5 mm.</p

Atom-Transfer Cyclization with CuSO₄/KBH₄: A Formal “Activators Generated by Electron Transfer” Process Also Applicable to Atom-Transfer Polymerization

The 4-<i>exo</i> and 5-<i>exo-trig</i> atom-transfer cyclizations of <b>1</b>,<b> 8a</b>–<b>e</b>, <b>9</b>, <b>12</b>, and <b>13</b> can be mediated with as little as 0.05 mol % of Cu­(TPMA)­SO₄·5H₂O in the presence of 2.5 mol % of borohydride salts in 10 min at room temperature in air. This formal “activators generated by electron transfer” (AGET) procedure utilizes a cheap and oxidatively stable copper source (CuSO₄·5H₂O) and can be carried out in environmentally benign solvents (EtOH). It is possible to alter the product distribution in the 5-<i>endo</i> radical–polar crossover reactions of <b>10a</b>,<b>b</b> and <b>11</b> by tailoring the amount of borohydride. Cyclization onto alkynes <b>14</b> and <b>15</b> is also possible in only 20 min. Controlled radical polymerization of styrene, with increased rates over conventional atom-transfer radical polymerization (ATRP), can be carried out in a controlled fashion (Mn, PDI) using either CuBr or CuSO₄·5H₂O and Bu₄NBH₄