103 research outputs found

    Efficient layering for high speed communication: the MPI over Fast Messages (FM) experience

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    We describe our experience of designing, implementing, and evaluating two generations of high performance communication libraries, Fast Messages (FM) for Myrinet. In FM 1, we designed a simple interface and provided guarantees of reliable and in-order delivery, and flow control. While this was a significant improvement over previous systems, it was not enough. Layering MPI atop FM 1 showed that only about 35 % of the FM 1 bandwidth could be delivered to higher level communication APIs. Our second generation communication layer, FM 2, addresses the identified problems, providing gather-scatter, interlayer scheduling, receiver flow control, as well as some convenient API features which simplify programming. FM 2 can deliver 55–95 % to higher level APIs such as MPI. This is especially impressive as the absolute bandwidths delivered have increased over fourfold to 90 MB/s. We describe general issues encountered in matching two communication layers, and our solutions as embodied in FM 2

    Effects of hydrogen on 4130 steel microstructure during tensile loading

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    The hydrogen effects on materials program at NIST-Boulder

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    Facial onset sensory and motor neuronopathy: new cases, cognitive changes and pathophysiology

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    Purpose of review To improve our clinical understanding of facial onset sensory and motor neuronopathy (FOSMN). Recent findings We identified 29 new cases and 71 literature cases, resulting in a cohort of 100 patients with FOSMN. During follow-up, cognitive and behavioral changes became apparent in 8 patients, suggesting that changes within the spectrum of frontotemporal dementia (FTD) are a part of the natural history of FOSMN. Another new finding was chorea, seen in 6 cases. Despite reports of autoantibodies, there is no consistent evidence to suggest an autoimmune pathogenesis. Four of 6 autopsies had TAR DNA-binding protein (TDP) 43 pathology. Seven cases had genetic mutations associated with neurodegenerative diseases. Summary FOSMN is a rare disease with a highly characteristic onset and pattern of disease progression involving initial sensory disturbances, followed by bulbar weakness with a cranial to caudal spread of pathology. Although not conclusive, the balance of evidence suggests that FOSMN is most likely to be a TDP-43 proteinopathy within the amyotrophic lateral sclerosis–FTD spectrum

    Domesticating Urban Theory? US Concepts, British Cities and the Limits of Cross-national Applications

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    The efficacy of the urban regime and growth machine concepts beyond the US remains a matter of considerable debate. Some argue that these frameworks retain considerable value so long as they are 'properly' applied and that recent concerns about the limits to these frameworks result from no more than their 'misapplication'. I critically examine this argument through a review of recent work on the mobilisation of business interests in British cities. The central claim is that, even when focused on the 'right' issues and questions, US frameworks quickly exhaust their explanatory capacity. In the context of a widening diversity of alternative approaches, I suggest that it is time to move squarely beyond growth coalition and regime accounts. The paper makes a number of suggestions for ways in which this new phase of theory building might proceed.Yeshttps://us.sagepub.com/en-us/nam/manuscript-submission-guideline
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