Additional file 1: of The associations between socioeconomic status and risk of Staphylococcus aureus bacteremia and subsequent endocarditis – a Danish nationwide cohort study

Incidence rate ratios of Staphylococcus aureus bacteremia according to SES. Incidence rate ratios (IRR) of Staphylococcus aureus bacteremia in accordance to SES stratified in two age groups (30–65 years and >65 years). The IRR are adjusted for calendar year, age and sex (highest SES used as reference). (EPS 137 kb

Additional file 2: of The associations between socioeconomic status and risk of Staphylococcus aureus bacteremia and subsequent endocarditis – a Danish nationwide cohort study

Incidence rate ratios of infective endocarditis in patients with Staphylococcus aureus bacteremia according to SES. Incidence rate ratios (IRR) of infective endocarditis in patients hospitalized with Staphylococcus aureus bacteremia prior to and after 2007 in accordance to SES. The IRR are adjusted for calendar year, age and sex (highest SES used as reference). (EPS 140 kb

Additional file 4: of The associations between socioeconomic status and risk of Staphylococcus aureus bacteremia and subsequent endocarditis – a Danish nationwide cohort study

Incidence rate ratios of Staphylococcus aureus bacteremia according to income. Incidence rate ratios (IRR) of Staphylococcus aureus bacteremia according to income stratified by age and adjusted for calendar year, age and sex (highest quartile used as reference). (EPS 115 kb

Characteristics of the three <i>S</i>. <i>haemolyticus</i> isolates found in the survey of conference participants.

1<p>Susceptibilities tested: linezolid, rifampicin, kanamycin, norfloxacin, erythromycin, clindamycin, fusidic acid, tetracycline, trimethoprim/sulfamethoxazole and mupirocin.</p

Characteristics of the eight MRSA isolates found in the survey of conference participants.

1<p>Susceptibilities tested: linezolid, rifampicin, kanamycin, norfloxacin, erythromycin, clindamycin, fusidic acid, tetracycline, trimethoprim/sulfamethoxazole and mupirocin.</p>2<p>Genome screened for <i>tetM</i> M21136, <i>tetK</i> NC_017331_REGION: 69118.70497, <i>msrSA</i> AB013298_487.1953, <i>mphC</i> NC_017351 REGION: 53170.54069, <i>ileS</i> AJJR01000036 REGION: 742.3816, <i>fusC</i> HE980450 REGION: 10019.10657, <i>ermA</i> NC_002745 _N315, <i>dfrG</i> AB205645 REGION: 1013.1510, AB568461 <i>Staphylococcus aureus aacA</i>-<i>aphD</i> gene for bifunctional AAC/APH, <i>gyrA</i> CP000046_COL, <i>rpoB</i> X64172 REGION: 1222.4770, <i>tetL</i> JN970906 REGION: 8454.9830, <i>ermC</i> NC007792 REGION: 7865.8599 <i>ermT</i> NC017673 REGION: 1795197.1795946.</p

A summary of the results from previous MRSA carriage surveys undertaken at veterinary or animal health conferences.

<p>ACVIM, The American College of Veterinary Internal Medicine; AAEP, American Association of Equine practitioners; ACVS, American College of Veterinary Surgeons.</p

Primers and TaqMan probes used to identify canonical single-nucleotide polymorphisms (canSNPs) that define the two major host-associated <i>S</i>. <i>aureus</i> CC398 clades.

a<p>TaqMan probes for the specific allele of the two canSNP states (underlined) were fluorescently labeled with either 6-FAM or VIC dye.</p>b<p>The genomic position was mapped to the chromosome (genes) of <i>S</i>. <i>aureus</i> CC398 strain SO385 (GenBank accession no. AM990992).</p

Maximum-parsimony tree of 89 <i>S. aureus</i> CC398 isolates based on 4,238 total SNPs, including 1,102 parsimony-informative SNPs.

<p>The bracket highlights the ancient human clade and the newly evolved livestock clade. Arrows indicate the position of the branch used to identify canSNPs, and isolates with unique <i>scn</i> and <i>tet</i>(M) patterns not consistent with the archetypal patterns are highlighted. The figure was adapted from Price <i>et al</i>. <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0079645#pone.0079645-Price1" target="_blank">[3]</a>.</p

List of bi-allelic, non-synonymous canonical single-nucleotide polymorphisms (canSNPs) that define the two major host-associated <i>S. aureus</i> CC398 clades.

a<p>canSNPs used in the study are underlined.</p>b<p>The genomic position was mapped to the chromosome (genes) of <i>S</i>. <i>aureus</i> CC398 reference strain SO385 (GenBank accession no. AM990992).</p