Slope estimates (the change in log odds for a 1% increase in <i>Froh</i>; points) and their 95% confidence intervals (bars) of <i>Froh</i> from the combined unimputed SNP data predicting schizophrenia for different SNP thresholds of calling ROHs.

<p>All SNP thresholds greater than 60 SNPs-in-a-row were significant.</p

Slope estimates (the change in log odds for a 1% increase in <i>Froh</i>; points) and their 95% confidence intervals (bars) of <i>Froh</i> from the combined unimputed SNP data predicting schizophrenia for different Mb thresholds of calling ROHs.

<p>All length thresholds longer than 1 Mb were significant.</p

Results of the INRICH pathway analysis.

<p>Results of the INRICH pathway analysis are shown in bar plot format. The x-axis shows negative logarithmic enrichment p-values for all nominally associated pathways containing two and more genes prior to- (gray) and after- (blue) correction for multiple testing. The red horizontal line indicates a p-value of 0.05.</p

Results of the Ingenuity Pathway Analysis.

<p>Results of the Ingenuity Pathway Analysis (IPA) are shown in bar plot format. The x-axis shows negative logarithmic enrichment p-values for all associated pathways containing two and more genes prior to- (gray) and after- (blue) Benjamini Hochberg correction for multiple testing. The red horizontal line indicates a p-value of 0.05.</p

IPA pathway synaptic long term potentiation.

<p>Results of the Ingenuity pathway analysis (IPA) for the pathway “Synaptic Long Term Potentiation” are shown. Shared schizophrenia-bipolar disorder associated genes (<i>GRIN2A</i>, <i>GRM3</i>, <i>CACNA1C</i>) are highlighted in purple.</p