Construct Validity Of Rorschach Space Responses

Background: The diagnostic meaning of the Space response, a Rorschach variable, is far from established. Previous studies on Rorschach Space responses suggested that different figure-ground relationships, shown in the three subtypes of Space responses (Integration, Reversal, and Fusion), could indicate different psychological processes. Objective: The aim of the current study was to investigate the construct validity of Space responses in a nonclinical sample by exploring the association of the three different types of Space responses with (a) the observer-rated motor, emotional, and cognitive components of aggression; and (b) the direction and emotional regulation of aggression in socially frustrating situations. Methods: The Rorschach Inkblot Method and the Rosenzweig Picture-Frustration Study were administered to 151 volunteers from a nonclinical community sample. The Aggression Questionnaire was administered as an observer-rated version to the participants' mothers. Correlation analyses were performed to investigate the associations between the three different Space responses, the scores reported on the Rosenzweig Picture-Frustration Study, and the observer-reported scores on the Aggression Questionnaire. Conclusion: This study offers support for differentiating the three types of mutually exclusive Space responses. Space reversal responses were found to be indicative of a propensity to direct aggression outward in the context of frustrating interpersonal situations, whereas Space fusion responses positively correlated with a greater amount of anger feelings and hostile thoughts associated with a deficit in anger and emotional regulation that may contribute to impair reality testing. As with previous studies, no association between S integration responses and anger or aggression was observed

Validity of Space Responses: What Can We Learn from Rorschach Protocols of Divorcing Couples Fighting for Child Custody?

Divorcing couples who require the intervention of the court system to resolve their child custody disputes usually exhibit intense anger and experience strong resentment. The Rorschach Inkblot Method (RIM) is one of the most commonly used tests in child custody evaluations, in which one crucial issue is affectivity and its regulation, and, specifically, negative emotions such as anger and resentment. White Space (S) is one of the Rorschach Comprehensive System (CS) variables usually taken into account to assess anger and resentment, but to date the construct validity of S responses for this purpose is far from established. Our study addresses this issue by exploring the association between S responses (coded on the basis of the following classifications: the CS, the Rorschach Performance Assessment System, and Rosso, Chiorri, and Denevi, 2015) and the motor, emotional, and cognitive components of aggression reported by clinicians in a sample of divorcing couples engaged in child custody litigation (n = 85). Our findings support the hypothesis that Space fusion responses may be a marker of separation and emptiness anxiety, whereas no support is provided by this study for the hypothesis that Space reversal and Space integration responses are indicative of anger

Interplay between <i>Helicobacter pylori</i> and host gene polymorphisms in inducing oxidative DNA damage in the gastric mucosa

Infection by Helicobacter pylori is the most important risk factor for gastric cancer. However, only a small fraction of colonized individuals, representing at least half of the world’s population, develop this malignancy. In order to shed light on host-microbial interactions, gastric mucosa biopsies were collected from 119 patients suffering from dyspeptic symptoms. 8-Hydroxy-20-deoxyguanosine (8-oxo-dG) levels in the gastric mucosa were increased in carriers of H.pylori, detected either by cultural method or by polymerase chain reaction, and were further increased in subjects infected with strains positive for the cagA gene, encoding the cytotoxin-associated protein, cagA. Oxidative DNA damage was more pronounced in males, in older subjects, and in H.pylori-positive subjects suffering from gastric dysplasia. Moreover, 8-oxo-dG levels were significantly higher in a small subset of subjects having a homozygous variant allele of the 8-oxoguanosine-glycosylase 1 (OGG1) gene, encoding the enzyme removing 8- oxo-dG from DNA. Conversely, they were not significantly elevated in glutathione S-transferase M1 (GSTM1)-null subjects. Thus, both bacterial and host gene polymorphisms affect oxidative stress and DNA damage, which is believed to represent a key mechanism in the pathogenesis of gastric cancer. The interplay between bacterial and host gene polymorphisms may explain why gastric cancer only occurs in a small fraction of H.pylori-infected individuals