First Synthesis of (20S) 3β,16β-Dihydroxy-5-pregnen-20,16carbolactone (Diosgeninlactone)

Abstract: Diosgeninlactone (1), a natural product from Solanum vespertilio, was stereoselectively synthesized in high yield from 3β-hydroxy-5-androstene

Personalized Subcutaneous Model-Predictive Closed-Loop Control of T1DM: Pilot Studies in the USA and Italy

none15B. Kovatchev; S. Anderson; M. Breton; S. Patek; D. Bruttomesso; A. Maran; S. Costa; A. Avogaro; L. Magni; D.M. Raimondo; G. De Nicolao; C. Dalla Man; A. Facchinetti; S. Guerra; C. CobelliB., Kovatchev; S., Anderson; M., Breton; S., Patek; D., Bruttomesso; A., Maran; S., Costa; A., Avogaro; Magni, Lalo; Raimondo, DAVIDE MARTINO; DE NICOLAO, Giuseppe; C., Dalla Man; A., Facchinetti; S., Guerra; C., Cobell

A multi-element psychosocial intervention for early psychosis (GET UP PIANO TRIAL) conducted in a catchment area of 10 million inhabitants: study protocol for a pragmatic cluster randomized controlled trial

Multi-element interventions for first-episode psychosis (FEP) are promising, but have mostly been conducted in non-epidemiologically representative samples, thereby raising the risk of underestimating the complexities involved in treating FEP in 'real-world' services