Association between bleeding severity score and platelet secretion testing results in 32 patients with primary secretion defects.

a<p>Adjusted for age at referral, sex, clinic of referral, region of residence.</p>b<p>Adjusted for sex, clinic of referral, region of residence.</p><p>CI, confidence intervals.</p

Diagnosis and bleeding severity score values in 207 patients.

<p>Patients with clinical bleeding or coagulation abnormalities and bleeding severity score of 4 or more are presented.</p>a<p>Including hemophilia A and B or rare bleeding disorders.</p>b<p>Includes δ-storage pool deficiency and Glanzmanńs thrombasthenia.</p>c<p>Secondary to drugs or to underlying medical conditions.</p>d<p>Individual values are reported.</p><p>BSS, bleeding severity score.</p

Relationships between measures of bleeding severity and pattern of platelet defect.

<p>The Figure shows the distribution of bleeding severity score (top), age-normalized bleeding severity score (middle) and age of first bleeding requiring medical attention (bottom) in patients with different patterns of platelet defect. The asterisk (*) indicates a patient with age-normalized bleeding severity score of 1.89. P-values were calculated by Kruskal-Wallis test.</p

Demographic, clinical and laboratory characteristics in 32 patients with primary secretion defects.

<p>a Number and percentage of patients showing reduced ATP secretion upon stimulation by the reported agonist at the reported concentration.</p><p>IQR, interquartile range; ADP, adenosine diphosphate; TRAP, thrombin receptor-activating peptide.</p

Flow-chart of the study population of patients with hepatocellular carcinoma.

<p>Flow-chart of the study population of patients with hepatocellular carcinoma.</p

Incidence rates of mortality and need of re-transplantation in patients with or without thrombosis.

<p>Incidence rates of mortality and need of re-transplantation in patients with or without thrombosis.</p

Characteristics of patients who underwent liver transplantation.

<p>Characteristics of patients who underwent liver transplantation.</p

Kaplan Meier curve for cumulative incidence of thrombosis after liver transplantation.

<p>Kaplan Meier curve for cumulative incidence of thrombosis after liver transplantation.</p

Characteristics of patients included in the nested case-control study.

<p>Characteristics of patients included in the nested case-control study.</p