Evaluation of the therapeutic efficacy of clindamycin in patients hospitalised with erysipelas

Introduction : Erysipelas is an acute skin infection of a streptococcal-related aetiology. Penicillin is the first-line antibiotic in the treatment of erysipelas; however, a number of other antibiotics are used. Aim of the research : To evaluate the clinical response of erysipelas to clindamycin in hospitalised patients. Material and methods : A retrospective cohort study was performed of all patients hospitalised with erysipelas and treated with the antibiotic clindamycin in Hospital de Base, São José do Rio Preto between 2000 and 2008. Results : The efficacy of this medication was evaluated. Failure of clinical treatment was detected in 4% of the 50 patients treated with clindamycin, but no failure was seen in 51 patients who were treated with clindamycin combined with other antibiotics. Conclusions : Clindamycin is clinically efficacious (96%) to treat patients hospitalised for erysipelas. Clindamycin is a good therapeutic option

Appendicular endometriosis as a cause of chronic abdominal pain alone in the right iliac fossa: case report and literature review

Endometriosis is a disease characterized by the presence of ectopic endometrial glands and stroma. Although its etiology is undefined, it is suggested to be a result of coelomic metaplasia, retrograde menstruation, to provide a genetic component, or to be one that occurs due to blood or lymphatic spread. The involvement of the gastrointestinal tract is common. However, appendicular endometriosis is a rare condition. It is usually asymptomatic. Recurrent pain in the right iliac fossa is an unusual clinical manifestation. There are no non-invasive complementary tests to confirm the diagnosis. Laparoscopy is the main option for research, due to its diagnostic and therapeutic features. A histopathological examination is necessary for the diagnosis. Although surgical and drug therapies have special indications, the combination therapy showed lower symptom recurrence. This study reports a case of appendicular endometriosis that was diagnosed and treated in the service of Coloproctology of the Base Hospital at Faculdade de Medicina of São Jose do Rio Preto. There is also a literature review about this situation