Short-Term Prognosis of Juvenile Myocardial Infarction: Role of Plasma Viscosity

In our early research1 regarding the hemorheological pattern in patients with acute myocardial infarction (AMI) with a mean age of 61.45 + 10.99 years, we showed that the major hemorheological parameters were almost normalized 2 weeks after the acute event. In the last decade, we focused on hemorheological parameters in juvenile myocardial infarction (JMI), defined as AMI in patients aged 45 years, in the \u2018\u2018Sicilian study on juvenile myocardial infarction\u2019\u2019

Cavity QED of Strongly Correlated Electron Systems: A No-go Theorem for Photon Condensation

In spite of decades of work it has remained unclear whether or not superradiant quantum phases, referred to here as photon condensates, can occur in equilibrium. In this Letter, we first show that when a non-relativistic quantum many-body system is coupled to a cavity field, gauge invariance forbids photon condensation. We then present a microscopic theory of the cavity quantum electrodynamics of an extended Falicov-Kimball model, showing that, in agreement with the general theorem, its insulating ferroelectric and exciton condensate phases are not altered by the cavity and do not support photon condensation.Comment: Reference list updated and minor typos correcte

Many-body localized quantum batteries

The collective and quantum behavior of many-body systems may be harnessed to achieve fast charging of energy storage devices, which have been recently dubbed quantum batteries. In this paper, we present an extensive numerical analysis of energy flow in a quantum battery described by a disordered quantum Ising chain Hamiltonian, whose equilibrium phase diagram presents many-body localized (MBL), Anderson localized (AL), and ergodic phases. We demonstrate that (i) the low amount of entanglement of the MBL phase guarantees much better work extraction capabilities, measured by the ergotropy, than the ergodic phase and (ii) interactions suppress temporal energy fluctuations in comparison with those of the noninteracting AL phase. Finally, we show that the statistical distribution of values of the optimal charging time is a clear-cut diagnostic tool of the MBL phase

QueryTogether: Enabling entity-centric exploration in multi-device collaborative search

Collaborative and co-located information access is becoming increasingly common. However, fairly little attention has been devoted to the design of ubiquitous computing approaches for spontaneous exploration of large information spaces enabling co-located collaboration. We investigate whether an entity-based user interface provides a solution to support co-located search on heterogeneous devices. We present the design and implementation of QueryTogether, a multi-device collaborative search tool through which entities such as people, documents, and keywords can be used to compose queries that can be shared to a public screen or specific users with easy touch enabled interaction. We conducted mixed-methods user experiments with twenty seven participants (nine groups of three people), to compare the collaborative search with QueryTogether to a baseline adopting established search and collaboration interfaces. Results show that QueryTogether led to more balanced contribution and search engagement. While the overall s-recall in search was similar, in the QueryTogether condition participants found most of the relevant results earlier in the tasks, and for more than half of the queries avoided text entry by manipulating recommended entities. The video analysis demonstrated a more consistent common ground through increased attention to the common screen, and more transitions between collaboration styles. Therefore, this provided a better fit for the spontaneity of ubiquitous scenarios. QueryTogether and the corresponding study demonstrate the importance of entity based interfaces to improve collaboration by facilitating balanced participation, flexibility of collaboration styles and social processing of search entities across conversation and devices. The findings promote a vision of collaborative search support in spontaneous and ubiquitous multi-device settings, and better linking of conversation objects to searchable entities

Flexible entity search on surfaces

Surface computing allows flexible search interaction where users can manipulate the representation of entities recommended for them to create new queries or augment existing queries by taking advantage of increased screen estate and almost physical tactile interaction. We demonstrate a search system based on 1) Direct Manipulation of Entity Representation on Surfaces and 2) Entity Recommendation and Document Retrieval. Entities are modeled as a knowledge-graph and the relevances of entities are computed using the graph structure. Users can manipulate the representation of entities via spatial grouping and assigning preferences on entities. Our contribution can help to design effective information exploration systems that take advantage of large surfaces

Ultra-stable charging of fast-scrambling SYK quantum batteries

Collective behavior strongly influences the charging dynamics of quantum batteries (QBs). Here, we study the impact of nonlocal correlations on the energy stored in a system of N QBs. A unitary charging protocol based on a Sachdev-Ye-Kitaev (SYK) quench Hamiltonian is thus introduced and analyzed. SYK models describe strongly interacting systems with nonlocal correlations and fast thermalization properties. Here, we demonstrate that, once charged, the average energy stored in the QB is very stable, realizing an ultraprecise charging protocol. By studying fluctuations of the average energy stored, we show that temporal fluctuations are strongly suppressed by the presence of nonlocal correlations at all time scales. A comparison with other paradigmatic examples of many-body QBs shows that this is linked to the collective dynamics of the SYK model and its high level of entanglement. We argue that such feature relies on the fast scrambling property of the SYK Hamiltonian, and on its fast thermalization properties, promoting this as an ideal model for the ultimate temporal stability of a generic QB. Finally, we show that the temporal evolution of the ergotropy, a quantity that characterizes the amount of extractable work from a QB, can be a useful probe to infer the thermalization properties of a many-body quantum system

Designing for Exploratory Search on Touch Devices

Exploratory search confront users with challenges in expressing search intents as the current search interfaces require investigating result listings to identify search directions, iterative typing, and reformulating queries. We present the design of Exploration Wall, a touch-based search user interface that allows incremental exploration and sense-making of large information spaces by combining entity search, flexible use of result entities as query parameters, and spatial configuration of search streams that are visualized for interaction. Entities can be flexibly reused to modify and create new search streams, and manipulated to inspect their relationships with other entities. Data comprising of task-based experiments comparing Exploration Wall with conventional search user interface indicate that Exploration Wall achieves significantly improved recall for exploratory search tasks while preserving precision. Subjective feedback supports our design choices and indicates improved user satisfaction and engagement. Our findings can help to design user interfaces that can effectively support exploratory search on touch devices

Crowdboard: Augmenting in-person idea generation with real-time crowds

Online crowds can help infuse creativity into the design process, but traditional strategies for leveraging them, such as large-scale ideation platforms, require time and organizational effort in order to obtain results. We propose a new method for crowd-based ideation that simplifies the process by having smaller crowds join in-person ideators during synchronous creative sessions. Our system Crowdboard allows online crowds to provide real-time creative input during early-stage design activities, such as brainstorming or concept mapping. The system enables in-person ideators to develop ideas on a physical or digital whiteboard which is augmented with real-time creative input from online participants who see and hear a live broadcast of the meeting. We validate Crowdboard via two user studies in which dyads of in-person ideators brainstormed with the help of crowd ideators. Our studies suggest that Crowdboard can effectively enhance ongoing brainstorming sessions, but also revealed key challenges for how to better facilitate interactions among in-person and crowd ideator

Persistent post-traumatic headache and migraine: Pre-clinical comparisons

Background: Oftentimes, persistent post traumatic headache (PPTH) and migraine are phenotypically similar and the only clinical feature that differentiate them is the presence of a mild or moderate traumatic brain injury (mTBI). The aim of this study is to describe the differences in brain area and in biochemical cascade after concussion and to define the efficacy and safety of treatments in use. Methods: Sources were chosen in according to the International Classification of Headache Disorder (ICHD) criteria. Results: The articles demonstrated a significant difference between PPTH and migraine regarding static functional connectivity (sFC) and dynamic functional connectivity (dFC) in brain structure that could be used for exploring the pathophysiological mechanisms in PPTH. Many studies described a cascade of neurometabolic changes that occur after traumatic brain injury. These variations are associated to the mechanism occurring when developing a PPTH. Conclusions: The state of art of this important topic show how although the mechanisms underlying the development of the two different diseases are different, the treatment of common migraine is efficacious in patients that have developed a post traumatic form

An uncommon presentation of eosinophilic granulomatosis with polyangiitis: a case report

INTRODUCTION: Eosinophilic granulomatosis with polyangiitis is a rare and potentially fatal disease if not readily diagnosed. Cerebral involvement is extremely rare and clinical presentation as hemorrhagic stroke is even rarer. CASE PRESENTATION: A 58-year-old Caucasian man was admitted to our medical unit because of a computed tomography-diagnosed hemorrhagic stroke with right-sided hemiparesis and fever. A chest computed tomography scan also revealed multiple bilateral pulmonary infiltrates; coronary artery, and carotid and left vertebral artery calcifications were also observed. Empiric antimicrobial therapy with cephalosporins was promptly undertaken; low-molecular-weight heparin was introduced as prophylaxis for venous thromboembolism. Over the following days, magnetic resonance imaging scans showed a regression of the hemorrhagic framework, also revealing hypoxic areas consistent with acute ischemic lesions. With a computed tomography scan showing a worsening of his pulmonary framework, antimicrobial therapy was modified and corticosteroids were introduced. A new blood cell count revealed further increased leukocytosis (17.49×10(3)μL), characterized by a surprising rise of eosinophilic cells (32.8%). Angiography of the coronary arteries found diffuse dilatations with severe signs of endothelial damage. Such an unexpected framework induced a strong suspicion that the stroke was the expression of a systemic vasculitis, which had triggered his cerebral, coronary, and pulmonary frameworks. The search for antineutrophil cytoplasmic antibody was positive for perinuclear antineutrophil cytoplasmic antibody, and eosinophilic granulomatosis with polyangiitis was diagnosed. Explaining to the patient the rarity of his disease, and what the most typical presentations of eosinophilic granulomatosis with polyangiitis were, he revealed that before admission he had had scalp injuries, in the nuchal region, and had taken corticosteroids as self-medication, with subsequent disappearance of the lesions. Therefore, high-dose corticosteroid treatment was started, and at discharge he was in good clinical condition with a slight right-sided hyposthenia. CONCLUSIONS: A diagnosis of eosinophilic granulomatosis with polyangiitis is often difficult, but we are convinced that intake of corticosteroids on a self-prescribed basis may have obscured the clinical presentation. Therefore, this case also suggests how the growing phenomenon of self-medication can be harmful, and that a careful investigation of clinical history is still an act of paramount importance