Agreement among panel members for 1st and 2nd round of the online Delphi questionnaire on the list of surgical steps generated by the hierarchical task analysis.

<p>Reformulations between round 1 and 2 are underlined, and deletions are in italic.</p

Additional file 2: Table S2. of Effect of driving pressure on mortality in ARDS patients during lung protective mechanical ventilation in two randomized controlled trials

Multivariate Cox regression analysis for factors on day 1 including plateau pressure associated with ARDS mortality at day 90. (DOC 33 kb

Comparison of scores for different components of total laparoscopic hysterectomy performed on a virtual reality simulator, as assessed by Hysterectomy Objective Structured Assessment of technical Skill scale, using case-volume criteria for definition of novice intermediate and experienced operators.

<p>Comparison of scores for different components of total laparoscopic hysterectomy performed on a virtual reality simulator, as assessed by Hysterectomy Objective Structured Assessment of technical Skill scale, using case-volume criteria for definition of novice intermediate and experienced operators.</p

Composition of the international expert panel for the online Delphi questionnaire.

<p>Composition of the international expert panel for the online Delphi questionnaire.</p

Spearman’s rank correlation between H-OSATS scores and OSATS scores for virtual reality laparoscopic hysterectomy.

<p>H-OSATS, Hysterectomy Objective Structured Assessment of Technical Skill; OSATS, Objective Structured Assessment of Technical Skills Global Rating Scale.</p

Comparisons of S-QoL 18 score means (SD) between homeless (n=236) and non-homeless individuals with schizophrenia (n=236) matched by age and gender.

<div><p>S-QoL 18—PsW: psychological well-being; SE: self-esteem; RFa: family relationships; RFr: relationships with friends; RE: resilience; PhW: physical well-being; AU: autonomy; and SL: sentimental life.</p> <p>* p < 0.05; ** p < 0.01.</p></div

Toward Meeting the Needs of Homeless People with Schizophrenia: The Validity of Quality of Life Measurement

<div><p>Objective</p><p>To provide new evidence regarding the suitability of using quality of life (QoL) measurements in homeless people with schizophrenia, we assess the acceptability and psychometric properties of a specific QoL instrument (S-QoL 18) in a population of homeless people with schizophrenia, and we compare their QoL levels with those observed in non-homeless people with schizophrenia.</p> <p>Methods</p><p>This multi-centre prospective study was conducted in the following 4 French cities: Lille, Marseille, Paris and Toulouse. Two hundred and thirty-six homeless patients with schizophrenia were recruited over a 12 month-period. The S-QoL 18 was tested for construct validity, reliability, external validity and sensitivity to change. The QoL of the 236 homeless patients was compared with 236 French age- and sex-matched non-homeless patients with schizophrenia.</p> <p>Results</p><p>The eight-factor structure of the S-QoL 18 was confirmed by confirmatory factor analysis (RMSEA = 0.035, CFI = 0.95, GFI = 0.99 and SRMR = 0.015). Internal consistency, reliability and sensitivity to change were satisfactory. External validity was confirmed via correlations between S-QoL 18 dimension scores and SF-36, symptomatology and recovery scores. The percentage of missing data did not exceed 5%. Finally, homeless patients had significantly lower QoL levels than non-homeless patients with schizophrenia.</p> <p>Conclusions</p><p>These results demonstrate the satisfactory acceptability and psychometric properties of the S-QoL 18, suggesting the validity of QoL measurement among homeless patients with schizophrenia. Our study also reported that QoL levels in homeless patients with schizophrenia were dramatically low, highlighting the need for new policies to eradicate homelessness and tackle poverty.</p> </div

Relevance of Quality of Life Assessment for Multiple Sclerosis Patients with Memory Impairment

<div><h3>Background</h3><p>Memory disturbances, in particular episodic verbal memory dysfunction, are the most frequent cognitive impairment observed in multiple sclerosis (MS) patients. The use of self-reported outcomes for evaluating treatment and managing care of these subjects has been questioned. The aim of this study was to provide new evidence about the suitability of self-reported outcomes for use in this impaired population by exploring the internal structure, reliability and external validity of a specific quality of life (QoL) instrument, the Multiple Sclerosis International Quality of Life questionnaire (MusiQoL).</p> <h3>Methods</h3><p><em>Design</em>: cross-sectional study. <em>Inclusion criteria</em>: MS patients of any disease subtype. <em>Data collection</em>: sociodemographic (age, gender, marital status, education level, and occupational activity) and clinical data (MS subtype, Expanded Disability Status Scale, disease duration); QoL (MusiQoL and SF36); and memory performance (Grober and Buschke test). In accordance with the French norms of the memory test, non-impaired and impaired populations were defined for short- and long-delay free composites and for short- and long-delay total composites. For the 8 populations, psychometric properties were compared to those reported from the reference population assessed in the validation study.</p> <h3>Principal Findings</h3><p>One hundred and twenty-four consecutive patients were enrolled. The analysis performed in the impaired populations showed that the questionnaire structure adequately matched the initial structure of the MusiQoL. The unidimensionality of the dimensions was preserved, and the internal/external validity indices were close to those of the reference population.</p> <h3>Conclusions/Significance</h3><p>Our study suggests that memory dysfunction did not compromise the reliability or validity of the self-reported QoL questionnaires.</p> </div

Psychometric properties of a QoL questionnaire: definitions.

<p>Psychometric properties of a QoL questionnaire: definitions.</p