Measuring exposure to bullying and harassment in health professional students in a clinical workplace environment : Evaluating the psychometric properties of the clinical workplace learning NAQ-R scale

Acknowledgments: The authors would like to thank all of the Associate Deans of Medical Education for Otago Medical School who assisted with the data collection for this questionnaire, as well as Faculty in The School of Nursing at Otago Polytechnic. We would also like to thank Dr Ella Iosua and Michel de Lange for their initial advice on the analysis of this paper. We would also like to thank the students for their time and effort in completing this questionnaire.Peer reviewedPostprin

Best Practice Guidance for Working with Transgender Community Members in Health Professional Teaching

The relationship between teaching staff and transgender community members is integral for the success of education sessions that these community members contribute to. In order for good learning outcomes for students, and a good experience for community members, there needs to be strong leadership from teaching staff. This manuscript contains best practice guidance for teaching staff and community members

The Olympic Games in Japan and East Asia: Images and Legacies: An Introduction

Introduction to The International Journal of Japanese Sociology Special Issue: 'The Olympic Games in Japan and East Asia: Images and Legacies,' edited by Mike Featherstone & Tomoko Tamar

Sport-related concussion research agenda beyond medical science: culture, ethics, science policy

The Concussion in Sport Group guidelines have successfully brought the attention of brain injuries to the global medical and sport research communities, and has significantly impacted brain injury-related practices and rules of international sport. Despite being the global repository of state-of-the-art science, diagnostic tools and guides to clinical practice, the ensuing consensus statements remain the object of ethical and sociocultural criticism. The purpose of this paper is to bring to bear a broad range of multidisciplinary challenges to the processes and products of sport-related concussion movement. We identify lacunae in scientific research and clinical guidance in relation to age, disability, gender and race. We also identify, through multidisciplinary and interdisciplinary analysis, a range of ethical problems resulting from conflicts of interest, processes of attributing expertise in sport-related concussion, unjustifiably narrow methodological control and insufficient athlete engagement in research and policy development. We argue that the sport and exercise medicine community need to augment the existing research and practice foci to understand these problems more holistically and, in turn, provide guidance and recommendations that help sport clinicians better care for brain-injured athletes

Functional diversity and co-operativity between subclonal populations of paediatric glioblastoma and diffuse intrinsic pontine glioma cells

The failure to develop effective therapies for pediatric glioblastoma (pGBM) and diffuse intrinsic pontine glioma (DIPG) is in part due to their intrinsic heterogeneity. We aimed to quantitatively assess the extent to which this was present in these tumors through subclonal genomic analyses and to determine whether distinct tumor subpopulations may interact to promote tumorigenesis by generating subclonal patient-derived models in vitro and in vivo. Analysis of 142 sequenced tumors revealed multiple tumor subclones, spatially and temporally coexisting in a stable manner as observed by multiple sampling strategies. We isolated genotypically and phenotypically distinct subpopulations that we propose cooperate to enhance tumorigenicity and resistance to therapy. Inactivating mutations in the H4K20 histone methyltransferase KMT5B (SUV420H1), present in <1% of cells, abrogate DNA repair and confer increased invasion and migration on neighboring cells, in vitro and in vivo, through chemokine signaling and modulation of integrins. These data indicate that even rare tumor subpopulations may exert profound effects on tumorigenesis as a whole and may represent a new avenue for therapeutic development. Unraveling the mechanisms of subclonal diversity and communication in pGBM and DIPG will be an important step toward overcoming barriers to effective treatments

Concussion ethics and sports medicine

Despite considerable scientific dispute the science of concussion, there has been a proliferation of position statements and professional guidelines published on sports concussion management over the last 15 years. A number of ethical and clinical problems associated with concussion management protocols remain concerning, (i) diagnosis and management; (ii) conflicts of interest and coercion; (iii) same day return to play; and (iv) reporting, auditing and confidentiality. These issues are critically discussed in the light of recent Consensus Statements. It is argued that the use of independent match day doctors may ameliorate some of these concerns