Association between quality of clinical practice guidelines and citations given to their references

It has been suggested that bibliometric analysis of different document types may reveal new aspects of research performance. In medical research a number of study types play different roles in the research process and it has been shown, that the evidence-level of study types is associated with varying citation rates. This study focuses on clinical practice guidelines, which are supposed to gather the highest evidence on a given topic to give the best possible recommendation for practitioners. The quality of clinical practice guidelines, measured using the AGREE score, is compared to the citations given to the references used in these guidelines, as it is hypothesised, that better guidelines are based on higher cited references. AGREE scores are gathered from reviews of clinical practice guidelines on a number of diseases and treatments. Their references are collected from Web of Science and citation counts are normalised using the item-oriented z-score and the PPtop-10% indicators. A positive correlation between both citation indicators and the AGREE score of clinical practice guidelines is found. Some potential confounding factors are identified. While confounding cannot be excluded, results indicate low likelihood for the identified confounders. The results provide a new perspective to and application of citation analysis.Comment: Paper submitted to 14th International Society of Scientometrics and Informetrics Conferenc

Hvordan motiverer man ligestilling

Omtale af Ea Høg Utoft: Motivation, organisational gender equality work and the postfeminist gender regime: A feminist approachOmtale af Ea Høg Utoft: Motivation, organisational gender equality work and the postfeminist gender regime: A feminist approac

Organic Food and Health: A new project to study the effects of plant cultivation methods (organic and conventional) on nutritional value, health and reproduction in an animal experiment

Many consumers believe that food from plants grown under certain conditions, such as organic agriculture, will benefit health more than conventional food. This cannot be determined simply by analysing the material, since our understanding of the connections between food components and health is still to imprecise for such a purpose. Rather than waiting until basic research provides the knowledge needed for this approach, in the spring of 2001 we have initiated a project to study physiological effects of plant quality directly, in an animal experiment. The following cultivation treatments are used to grow plants that are typical ingredients for a human diet (potato, mature peas, kale, spring wheat, oilseed rape, carrots and apples): 1. A model of a distinct conventional cultivation system, with high input of mineral nutrients and use of as much pesticides as is allowed. 2. A model of a distinct organic cultivation system, with low input of organic plant nutrients and no use of pesticides. 3. A combination of model 1 and 2, with low input of nutrients and use of pesticides. The materials from each cultivation treatment will be thoroughly characterised, by measuring contents of nutrients (protein, minerals, energy content, vitamins), the biological value of major protein sources of feed plants will be assessed, selected secondary metabolites including known anti-nutrients will be measured and other quality indicators will be assessed including biocrystallization. Based on these results, 3 feed mixtures will be prepared, either based on defined weight percentages of each material from each treatment, or, if large variation in biological value is found, one or two feed mixtures can be adjusted to provide the same availability of protein and energy as the reference treatment (model 1). Potato, mature peas and kale will be cooked and freeze-dried, wheat is ground and baked to biscuits, oil is produced from the rapeseed, and raw carrots and apples are shredded and freeze dried, before feed pellets with the desired composition are prepared from the material. Three groups of rats are each provided one of the dietary treatments during 2.5 generation, and reproductive characteristics and performance are recorded. Subgroups of the last generation are selected for an intensive study in which uptake and excretion of energy and protein and selected micronutrients are determined. Respiration trials are performed to assess the energy metabolism, and simultaneous measurements of the activity levels of the rats are performed. In addition, blood and tissue samples of the rats will be obtained to study the effect of the dietary treatments on the immunological and antioxidant status of the rats. Data from the experiments are assembled and analysed using relevant statistical models, and the relationship to the nutritional characteristics of the plant material is described. Funding for the core project for a 4-year period is secured from the Danish Research Centre for Organic Farming (DARCOF). However, the intention is to provide a platform for international collaboration, since the well-documented material of plants and animals can provide multiple opportunities for associated projects. To investigate other aspects of plant composition or health than what is foreseen in the present project, or to follow up on it with additional experiments

Økologiske fødevarer og menneskets sundhed

Økologiske fødevarer er genstand for stigende forbrugerinteresse og politisk opmærksomhed i hele den vestlige verden i disse år. Det er i den forbindelse blevet et stadig væsentligere tema hvorvidt økologiske fødevarer kan anses for at have særlige sundhedsfremmende og sygdomsforebyggende egenskaber. På anbefaling af Det Økologiske Fødevareråd bevilgede Strukturdirektoratet i efteråret 1999 derfor midler til at få samlet den faktuelle viden om økologiske fødevarers sundhedsmæssige betydning. Det Økologiske Fødevareråd anbefalede at denne sammenstilling af viden skulle benyttes som fundament for iværksættelse af ny forskning til yderligere belysning af emnet