Derecho de Sucesiones

La muerte de una persona es uno de los hechos jurídicos que mayor trascendencia acarre dentro del ordenamiento jurídico, no solo por implica el fin de la existencia de la persona, sino por todas aquellas consecuencia de índole patrimonial que ocasiona; por esta razón, su inclusión se convierte en un imperativo categórico para la buena formación del estudiantado. La prolongación de la personalidad jurídica del difunto en sus herederos es una de la ficciones legales de mayor importancia, de forma que constituye el mecanismo por medio del cual la ciencia jurídica ha configurado la transmisión de tanto de los derechos como de las obligaciones del de cuius, así se proporciona una efectiva seguridad jurídica concretada en el hecho de que, salvo en el caso de los derechos y obligaciones personalísimos, todas, las relaciones patrimoniales de la persona no extinguen por el hecho de su fallecimiento. Para comprender la trascendencia y significancia del Derecho sucesorio y de sus instituciones es insoslayable estudiar sus orígenes en Derecho romano, así como su evolución histórica; de esta manera, el estudiantado tendrá una visión integral de la materia objeto de nuestro estudio

Additional file 1: Table S1. of IgG Fc galactosylation predicts response to methotrexate in early rheumatoid arthritis

Demographic characteristics of the nationwide EIRA cohort. Table S2. Characterized complement pathway proteins and IgG-isotype proteins. Table S3. Individual IgG-Fc glycan distribution values in IgG1 and in IgG2 in control subjects, as well as in patients with RA prior to and following MTX treatment. Table S4. Significant differences for the 19 characterized glycan species when comparing healthy versus all, good, moderate, and nonresponding patients prior to and following MTX treatment. Table S5. IgG1 and IgG2 Fc glycan distributions grouped according to structural features, comparing healthy control subjects and patients with RA prior to and following MTX treatment. Table S6. Intra- and interindividual differences in the patients with RA, comparing individual glycan species prior to and following MTX treatment. Table S7. Complete list, ranking, and correlation (with response versus no response to MTX) of the features used in the OPLS-DA model shown in Fig. 3b. Figure S1. Extracted ion chromatograms of IgG1 and IgG2 Fc glycans quantified in a control subject and a patient with RA. Figure S2. Intraindividual changes in galactosylation status on IgG1 and on IgG2 for good and moderate responders and for nonresponders. Figure S3. Intraindividual correlation between the aGal/Gal status of glycans with different types of structural features and of IgG1 and IgG2 substituted glycans. Figure S4. Significant differences between control subjects and patients with early RA at baseline in the classical pathway initiating complements C1 and C9. Figure S5. Intraindividual correlation between the classical and lectin pathway inhibitor C4bBPα versus FA2/(FA2G1 + FA2G2). (DOCX 1180 kb

MOESM1 of Increased citrullination and expression of peptidylarginine deiminases independently of P. gingivalis and A. actinomycetemcomitans in gingival tissue of patients with periodontitis

Additional file 1: Figure S1. Expression of citrullinated proteins. Another representative example of citrullinated proteins staining in gingival tissue sections obtained from patients with periodontitis and periodontally healthy controls (non-periodontitis). Magnification 250x (scale bars 100 Îźm)

MOESM2 of Increased citrullination and expression of peptidylarginine deiminases independently of P. gingivalis and A. actinomycetemcomitans in gingival tissue of patients with periodontitis

Additional file 2: Figure S2. Detection of P. gingivalis and leukotoxins of M. haemolytica and A. actinomycetemcomitans in gingival biopsies from healthy patients without periodontitis. Representative immunohistochemistry images of gingival biopsies are shown. Magnification 100x and 2x zoom-in on the area of interest (scale bars 100 μm). E = Epithelium; CT = Connective Tissue

Additional file 1: of Antibodies to carbamylated Îą-enolase epitopes in rheumatoid arthritis also bind citrullinated epitopes and are largely indistinct from anti-citrullinated protein antibodies

Supplementary tables and methods. Table S1 Îą-enolase peptide sequences. Table S2 Association between PTPN22 polymorphism and RA in subgroups of patients, divided based on the presence/absence of anti-CEP-1 and anti-carb-CEP-1 IgG. (DOCX 22 kb

Patient characteristics and summarised results.

<p>Patient characteristics and summarised results.</p

The prevalence of hcmv-miR-UL112-3p was determined using a TaqMan miRNA assay, and the seroprevalence of IgG and IgM against HCMV was detected with ELISA assays in all patients and controls.

<p>HC = Healthy Controls, GBM = Glioblastoma multiforme, RA = Rheumatoid Arthritis and DM = Diabetes Mellitus (patients from the DIGAMI-2 cohort).</p

TaqMan assay standard curve plot (left) and amplification plot (right): For miRNA copy number quantification; standard curve was prepared from ten time dilutions of recombinant plasmid containing hcmv-miR-UL112-3p amplicon as insert, which was used as a template in TaqMan miRNA assays.

<p>TaqMan assay standard curve plot (left) and amplification plot (right): For miRNA copy number quantification; standard curve was prepared from ten time dilutions of recombinant plasmid containing hcmv-miR-UL112-3p amplicon as insert, which was used as a template in TaqMan miRNA assays.</p

Additional file 6: Figure S5. of The lung microbiota in early rheumatoid arthritis and autoimmunity

Optimal Bayesian network analysis at the genus level. Green circles = taxa; blue circles = metadata; black lines = positive correlations; blue lines = negative correlations. (JPEG 149 kb

Additional file 2: Figure S1. of The lung microbiota in early rheumatoid arthritis and autoimmunity

Unweighted UniFrac distance metric was used to compare BAL microbial communities within and between groups. Healthy BAL community structure was significantly different from sarcoid (A) and RA (B). By contrast, sarcoidosis and RA groups revealed a closer relative relatedness of taxonomic composition (C). (JPEG 146 kb