Social and Environmental Issues in Corporative Management: A Romanian Story

The complex process of monitoring entities environmental impact entails ability, respect for the environment and reduction of the ecological footprint. This research defines Romanian trends as regards the effects and actions to adapt to climate change and characterizes corporate management in terms of compliance with environmental management systems requirements. The main objective is to assess the current state of environmental management implementation and identifies relevant social and environmental issues that companies use to include in corporate management. The current agenda would allow developing a framework for environmental management implementation in Romanian entities, in order to assume the corporate social responsibility

EXTREME CEREBRAL MALFORMATION – CLINICAL AND ETHICAL ISSUES BASED ON A CASE

Hydranencephaly represents one of the most rare cerebral malformations, with poor prognosis and negative impact on both family and society. Usually the patients remain in a permanent vegetative state and require unlimited medical care. Although the majority of affected babies die in utero or in the fi rst days-months of life there have been cases in literature with prolonged survival, for 20 (1), 22 (2) and 32 (3) years. Therapeutically, the medical care provided are purely palliative and oriented to supporting vital function. Conclusions. Hydranencephaly is a rare brain malformation with poor prognosis, life expectancy and quality of life. Diagnosis imposes a number of ethical issues. The importance resides in the fact that prenatal detection represents an indication for therapeutic abortion. Another ethical issue raised is represented by medical care provided, which is exclusively palliative. Both surgical and novel therapeutic methods described by the literature, like endoscopic coagulation of choroid plexes, do not infl uence the neurological status and the neuropsychomotordevelopment (4). All this data should be clearly explained to parents and legal tutors for not raising any false hopes regarding the evolution

The prevalence and risk factors for visceral hemangiomas in children with infantile cutaneous hemangiomas

One of the most frequent benign tumor pathology in children is represented by infantile hemangiomas (IHs). Although they are mostly cutaneous, sometimes they can develop at visceral level, the liver being the most common localization. Objectives. Estimating visceral hemangiomas (VHs) prevalence, and identification of risk factors for VHs in patients with infantile cutaneous hemangiomas (ICHs). Materials and methods. 6 years cross-sectional study (2012-2017) including children diagnosed with ICHs, admitted in I.N.S.M.C “Alfred-Rusescu“. All patients underwent an ultrasound screening for the detection of VHs. In order to identify possible risk factors, we collected demographic and perinatal data. Outcomes. 138 patients diagnosed with infantile cutaneous hemangiomas (ICHs) were included, with a slight predominance of girls (58%). The prevalence of the VHs in our study was 7,24% (10 patients). The liver was the most common visceral localization (7 patients). Conclusions. Female gender, preterm birth, low birth weight, and multiple gestations were described as potential risk factors for IHs. In our study, only multiple gestations tend to be associated with visceral hemangiomas, but without a significant statistical correlation

QUESTIONNAIRE ON FOREIGN LANGUAGE LEARNING STYLES FOR BUSINESS AND ENGINEERING STUDENTS

Our current approach offers an opportunity to analyse the trends in a wide range of educational topics, policies and best practice over the past decade and to assess the challenges lying ahead. We hope that this body of data and information will serve as a valuable source for decision makers in various education areas. Reviewing and reforming educational strategies need to be performed so as to ensure access to high quality instruction and training for all citizens, thus facilitating long-term socio-economic growth and stability. This study analyses the main young adult English learning styles & strategies used in acquiring and improving the communicative competence in English for effectively meeting the demands of the future career. The labour market nowadays is characterized by rapid changes in technology, spectacular developments, higher standards and unprecedented mobility and comfort. All these have essentially changed the way we live and communicate, generating the need for lifelong learning, not only for jobs, but also for active and creative adaptation to the rhythm of common daily life. Foreign language(s) communication competences, as well as computer skills, are indispensable for meeting the current employment standards

Candidate proteomic biomarkers for non-alcoholic fatty liver disease (steatosis and non-alcoholic steatohepatitis) discovered with mass-spectrometry: a systematic review

<p><i>Context</i>: Non-alcoholic fatty liver disease (NAFLD) is characterized by lipid accumulation in the liver which is accompanied by a series of metabolic deregulations. There are sustained research efforts focusing upon biomarker discovery for NAFLD diagnosis and its prognosis in order investigate and follow-up patients as minimally invasive as possible.</p> <p><i>Objective</i>: The objective of this study is to critically review proteomic studies that used mass spectrometry techniques and summarize relevant proteomic NAFLD candidate biomarkers.</p> <p><i>Methods</i>: Medline and Embase databases were searched from inception to December 2014.</p> <p><i>Results</i>: A final number of 22 records were included that identified 251 candidate proteomic biomarkers. Thirty-three biomarkers were confirmed – 14 were found in liver samples, 21 in serum samples, and two from both serum and liver samples.</p> <p><i>Conclusion</i>: Some of the biomarkers identified have already been extensively studied regarding their diagnostic and prognostic capacity. However, there are also more potential biomarkers that still need to be addressed in future studies.</p

MALFORMAŢIE CEREBRALĂ EXTREMĂ – CONSIDERAŢII CLINICE ŞI ETICE PE MARGINEA UNUI CAZ

Rezumat. Hidranencefalia reprezintă una dintre malformaţiile cerebrale extrem de rară şi cu prognostic nefavorabil, cu impact psihoafectiv negativ asupra familiei şi societăţii. În mod obişnuit, cei afectaţi rămân într-o stare vegetativă permanentă şi necesită îngrijiri pe termen nelimitat. Deşi majoritatea celor afectaţi decedează în primele zile-luni de viaţă, o parte dintre ei supravieţuiesc până în decada a 2-a a 3-a de viaţă. Din punct de vedere al tratamentului, îngrijirile acordate sunt pur paliative şi sunt îndreptate spre menţinerea funcţiilor vitale. Concluzii. Hidranencefalia reprezintă o malformaţie cerebrală rară, cu prognostic rezervat şi speranţă de viaţă şi calitate a vieţii scăzute. Diagnosticul impune o serie de probleme etice. Importanţa diagnosticului prenatal se impune prin faptul că hidranencefaliare prezintă indicaţie de avort terapeutic. O altă problemă etică o ridică îngrijirile medicale acordate, ce sunt pur paliative, pacienţii fi ind în stare vegetativă permanentă. Atât instituirea tratamentului chirurgical pentru drenajul cantităţii excesive al LCR, cât şi metodele noi terapeutice descrise în literatură, de tipul coagulării endoscopice a plexurilor choroide, nu infl uenţează statusul neurologic şi dezvoltarea neuropsihomotorie a pacienţilor. Toate aceste date trebuie explicate clar aparţinătorilor, pentru a nu-şi ridica speranţe false în ceea ce priveşte evoluţia acestor bolnavi

INFANTIL CUTANED HEMANGIOMATOSIS ASSOCIATED WITH MULTIFOCAL HEPATIC HEMANGIOMATOSIS – CASE PRESENTATION

Infantile hemangiomas are the most frequent tumors of infancy, with an incidence reaching almost 10% (1). In children with more than 5 skin hemangiomas it has been noticed a highly association with visceral hemangiomas, the liver being the main site for their localization (2). Regarding therapeutic approach, if for skin hemangiomas the treatment is well established, for hepatic infantile hemangiomas clear guidelines are still necessary

PERI-INTRAVENTRICULAR HEMORRHAGE IN PRETERM INFANTS: THE IMPORTANCE OF SCREENING BY TRANSFONTANELLAR ULTRASOUND

Objectives. In preterm babies, peri-intraventricular hemorrahges (PIVH) might cause various degrees of neuropsycho-motor impairment. A 4-year prospective study (2009-2012) performed in the IOMC, was aimed to determine the prevalence of different degrees of PIVH diagnosed by head ultrasound (HUS) among 160 admitted preterm babies, the associated risk factors, along with the neuro-developmental effects on a 12-month follow-up period. Material and methods. In the above-mentioned period all admitted preterms were examined by transfontanelar ultrasound according to a standardized protocol based on Papile’s PIVH classifi cation. For those preterms included in the study a 12-month systematic neurologic follow-up was performed. Results. PIVH grade I (45%) and II (37,5%) were the most prevalent types. Grade IV PIVH represented 4,4% from all PIVH cases. The good neurological outcome of grade I and II PIVH, was found to be statistically signifi cant (p < 0.01) for both types. Severe neurological sequelae were associated with grade III and IV and a statistically signifi cant correlation (p<0.01) was found only for grade IV hemorrhages. Conclusion. Systematic HUS screenings for all preterm babies is useful for early diagnosis and PIVH staging, for neurologic outcome prediction, providing the appropriate management strategy and a well-suited parental counseling

HEMORAGIA PERI-INTRAVENTRICULARĂ LA PREMATURI: IMPORTANŢA SCREENINGULUI PRIN ECOGRAFIE TRANSFONTANELARĂ

Obiective. Hemoragiile peri-intraventriculare (HPIV) pot determina la sugarii născuţi prematur diferite grade de re tard neuropsihomotor. Un studiu prospectiv efectuat în IOMC pe o perioadă de 4 ani (2009-2012), pe un lot de 160 prematuri, a urmărit prevalenţa gradelor de HPIV diagnosticate prin ecografi e transfontanelară (ETF), identifi carea factorilor de risc asociaţi şi a severităţii afectării neurologice la aceşti pacienţi prin urmărirea lor pe o perioadă de 12 luni. Material şi metodă. Pe perioada studiului, prematurii internaţi în IOMC au fost examinaţi sistematic prin ETF, printr-un protocol standardizat; aprecierea gradelor HPIV s-a efectuat conform clasifi cării Papile. Evaluarea neurologică a fost efectuată sistematic până la vârsta de 1 an. Rezultate. Cel mai frecvent înregistrate au fost HPIV I şi II – 45%, respectiv 37,5% din numărul total de pacienţi. HPIV gradul IV au reprezentat 4,4%. În HPIV grad I şi II afectarea neurologică a fost uşoară, această corelaţie având semnifi caţie statistică (p < 0,01) pentru ambele forme. Hemoragiile gradul III şi IV au fost asociate cu o evoluţie neurologică nefavorabilă, corelaţia între HPIV grad IV şi sechelele neurologice majore având semnifi caţie statistică (p < 0,01). Concluzii. ETF efectuată de rutină tuturor prematurilor permite diagnosticul precoce şi stadializarea HPIV, aprecierea evoluţiei neurologice cu instituirea precoce a tratamentului şi asigurarea consilierii adecvate