4 research outputs found

    Guided Modes in the Plane Array of Optical Waveguides

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    It is known that for an isolated dielectric cylinder waveguide there exists the cutoff frequency ω∗\omega_\ast below which there is no guided mode. It is shown in the paper that the infinite plane periodic array of such waveguides possesses the guided modes in the frequency domain which is below the frequency ω∗\omega_\ast. In the case of a finite array, the modes in this frequency domain are weakly radiating ones, but their quality factor QQ increases with the number of waveguides NN as Q(N)∼N3Q(N)\sim N^3. This dependence is obtained both numerically, using the multiple scattering formalism, and is justified with a simple analytical model

    Evaluation of effectiveness of solvent-detergent viral in activation in the manufacture of intravenous human immunoglobulin G in a model of virus diarrhea — mucosal disease of cattle

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    In model experiments using in vitro virus diarrhea — mucosal disease in cattle (bovine VD-MDC) studied the effectiveness of solvent-detergent (SD) virus inactivation used in the production of intravenous human immunoglobulin G (IgG). Optimized conditions for SD processing of immunoglobulin: the final concentration of tributylphosphate (TBP) 0.3% 0.2% sodium cholate, process temperature of 30 ± 1 °C to 36 ± 1 °C, incubation time 6 hours. The level of reduction of VD-MDC in the processing of the drug in these conditions was more than 6 log 10 TCD 50/ml
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