Routines, Reconfiguration and the Contribution of Business Analytics to Organisational Performance

Availability of large volumes of data in the firms has given a rise in interest in the potential use of business analytics applications. Research has investigated the potential of business analytics to deliver improved performance and competitive advantage at the firm level. However, a theoretical framework identifying the organisational factors which enables the firms to realise those performance gains and competitive advantage has not been clearly articulated. This paper proposes a theoretical framework identifying the organisational factors involved in realising performance gains and competitive advantage from business analytics. This paper draws on the foundational works of dynamic capabilities, routines and effective use to develop a research model. The data collected to test the research model is described along with the analytical strategies to test the model. Implications for research and practice are discussed

Comparative analysis between dynamic hip screw with trochanteric stabilisation plate and dynamic hip screw alone in the management of unstable intertrochanteric femur fractures

Background: Intertrochanteric fractures of the femur are difficult to manage because of the complex patterns they present with. A dynamic hip screw (DHS) and a DHS supplemented with a trochanteric stabilisation plate (TSP) are among a variety of fixation methods used in the management of such injuries. We compared the efficacy of DHS with TSP to DHS alone in the treatment of unstable intertrochanteric femur fractures.Methods: 30 patients of intertrochanteric femur fractures (mean age 72 years) were included in the study, 14 were treated using DHS with TSP while 16 were treated using DHS alone, they were followed up till 16 weeks and the progress was recorded according to the parameters in the Salvati and Wilson score.Results: 14 patients were treated using DHS with TSP, 11 of them had excellent Salvati and Wilson scores, 3 patients recorded good scores, 11 patients were able to walk with no pain while 3 needed aids for walking due to pain, normal function was restored in 12 patients while very little restriction was seen in 2 patientsOf the16 patients treated using DHS alone, 10 had excellent scores, 6 recorded a good score, 10 patients walked with no pain while 6 needed aids for walking due to pain, normal function was re-stored in 11 patients, very little restriction was seen in 4 patients while 1 patient had restricted nor-mal activity.Conclusions: DHS with TSP appears to provide better fixation and functional outcome in unstable inter trochanteric fractures over DHS alone

Who kicks whom?\u3csup\u3e1\u3c/sup\u3e Contextual and Temporal Effects in the IT Use - Performance Relationship

This research extends extant literature examining the relationship between IS use and performance. While prior theory has predominantly treated IS use as an antecedent of performance and hypothesized a positive effect of use on performance, this research provides an alternative perspective. Specifically, this paper theorizes that under certain contexts performance can be an antecedent of use and that the effect can be in the opposite direction. In contrast to non-contingent models, this paper proposes a contingent model in which the IS use-performance relationship is contingent on organizational performance and varies over time. The model proposed here is tested on longitudinal data. Distributed lag model was employed for data analysis. The results support our hypotheses that performance is an antecedent of IS use and that the effect is negative, i.e. when organizational performance declines, IS use increases but after a period of increased use, the effect declines to non-significant levels

How Organizational Performance Influences Managerial Search? – Towards ‘Informating Search’ Theory

Although we expect managers to use the capabilities of business analytics systems to search for solutions and improve firm performance, we do not have a good understanding of the factors that motivate managers to undertake such search. Drawing on attribution and control theories, we propose a theory that explicates the performance conditions under which managers undertake search activities. Specifically, we theorize that managers are motivated to search for knowledge when both, operational performance and overall organizational performance, are declining. Further, we propose that managers’ search response to sustained organizational performance failure is faster (low search latency) when the magnitude of sustained failure is larger. We tested our hypotheses with longitudinal data collected monthly over a period of four years from seven hospitals. Distributed lag model analysis of the data supports our hypotheses. We conclude with implications for research and practice, and plans for future research

SIMULTANEOUS ESTIMATION OF PROPAFENONE AND ITS TWO METABOLITES IN HUMAN PLASMA BY LIQUID CHROMATOGRAPHY/TANDEM MASS SPECTROMETRY LC-MS/MS

Objective: A simple, sensitive and rapid performance liquid chromatography/positive ion electrospray tandem mass spectrometry method was to be developed and validated for quantification of propafenone (PPF) and its two major metabolite 5-hydroxy propafenone (5-OHP) and N-depropyl propafenone (NDP) in human plasma.Methods: Liquid-liquid extraction (LLE) with ethyl acetate was used of extraction of plasma samples. The analytes were separated using an isocratic mixture of 0.1% formic acid/acetonitrile (20:80 v/v) on a reversed-phase column Hypurity Advance C18 50 x2.1 mm, 5µ and analysed by mass spectrometry in the multiple reaction monitoring mode using the respective [M+H] Ions. The m/z was 342.20/116.10 for propafenone, m/z 299.80/74.10 for N depropyl propafenone and m/z 358.30/98.10 for 5-hydroxy propfenone along with m/z 409.2/238.0 for Amlodipine as internal standard respectively.Results: The method had a short chromatographic run time of 1.5 min. The method exhibited a linear dynamic range over 5.11 to 1000.73 ng/ml for propafenone, 0.51 to 100.06 ng/ml for N-depropyl propafenone and 5.11 to 1001.64 ng/ml for 5-hydroxy propafenone respectively, in human plasma.Conclusion: The validated method has been successfully used to analyze human plasma samples for application in pharmacokinetics, bioavailability and bioequivalence studies

Evaluation of apparent diffusion coefficient in endometrial carcinoma compared to normal endometrium: a retrospective study

Background: To determine whether diffusion-weighted imaging (DWI) with measurement of apparent diffusion coefficient (ADC) will help in differentiating endometrial cancer from normal endometrium and to determine whether the grades of endometrial cancer will show significant difference in ADC values.Methods: This is a retrospective study done in MOSC medical college hospital Kolencherry. on patients on whom preoperative MRI was done before hysterectomy. Cases from July 2017 to March 2021 were included. Study cases included 40 females with pathologically confirmed endometrial cancer and 30 females with pathologically proven normal endometrium in cases of uterine leiomyoma and cervical cancer. The exclusion criteria for the study were patients with endometrial cancer in whom surgery was not done within 2 weeks of MRI, patients who were treated with chemotherapy or radiotherapy before surgery, patients who had hydrometra or pyometra.Results: The mean ADC value (10−3 mm2/second) of endometrial cancer was 0.77±0.04, which was significantly lower (p0.05).Conclusions: Our study showed that ADC measurement can differentiate between normal endometrium and endometrial cancer. The ADC values of different grades of endometrial cancers did not show any statistically significant difference.

The Effects of Firm IT Capabilities on Firm Performance: The Mediating Effects of Process Improvement

Prior research has examined the direct relationship between the firm IT capabilities and firm performance. Here, we extend that stream of literature and examine the mediating effects of performance at the process level on the relationship between firm IT capabilities and firm performance. This paper draws on the resource-based theory and the dynamic capabilities perspective to develop a theoretical framework to examine the mediated effects. The results suggest that the effect of firm IT capabilities on firm performance is fully mediated through performance at the process level

Assessment of the outcome of fracture proximal humerus transdeltoid versus deltopectoral approach with PHILOS

Introduction: Fracture proximal humerus accounts for 4 percent of all fractures. Out of all the humerus fractures, proximal fractures accounts for 26%. According to the Neer’s classification, 2, 3- and 4-part fracture are difficult to achieve stable fixation. In this study, we want to assess whether the different surgical approach, deltopectoral and transdeltoid approach, used for the stabilization of the fracture proximal humerus effects on the outcome of the surgery.Method: A total of 30 patients with fracture proximal humerus 2, 3 and 4-part were included in this study and were divided into 2 groups. In group 1, 15 patients were taken and were operated by deltopectoral approach, while in group 2, 15 patients were taken and operated by transdeltoid approach. All the fixation was done by PHILOS.Result: In group 1, out of 3 patients having 2-part fracture, 2 had excellent result and 1 had fair result. Out of 4 patients having 3-part fracture, 3 had good outcome and 1 had fair result. Out of 6 patients having 4-part fracture, 1 had good outcome. In group 2, out of the 3 patients having 2-part fracture, 1 had excellent outcome and 2 had good outcome. Out of the 4 patients having 3-part fracture, 1 had excellent outcome, 3 had good outcome. Out of the 6 patients having 4-part fracture, 3 had good result.Conclusions: Deltopectoral approach is recommended for calcar reconstruction that provides better visibility of medial calcar reduction while transdeltoid approach is recommended for greater tuberosity reduction that provides better visibility of greater tuberosity

A study of the association between hyperuricemia and knee osteoarthritis in the coastal Indian population

Background: Hyperuricemia and knee osteoarthritis are common problems that affect the aging population and they have an increasing prevalence with obesity and hypertension. Epidemiologic and immunological studies have shown a possible relation between the two conditions. Uric acid is a common factor found in association with the evaluation and treatment of osteoarthritis. There are serious therapeutic implications, particularly in using traditional gout medications, for use in osteoarthritis treatment is to be explored in detail. Our diet contains a good amount of purine containing food stuffs. The common items which increase our uric acid levels are red meat, all alcoholic beverages, seafood and shellfish. Previous studies have shown an association between serum uric acid and generalized osteoarthritis, but with the limited studies on the evidence of association between serum uric acid and knee joint osteoarthritis. This study aims to know the association between serum uric acid levels and osteoarthritis of knee joint.Methods: This is a Cross-sectional analytical study including eight hundred and thirty patients (461 males, 369 females) in a population screening during a patient education program on joint pains. Their serum uric acid level, total count, differential count, erythrocyte sedimentation rate (ESR), height, weight, blood pressure, BMI and standing radiographs of affected knees were obtained. The presence of radiographic osteoarthritis of the knee was analyzed using Kellgren-Lawrence system. The patients were divided into cohorts with hyperuricemia and osteoarthritis and compared with the subjects without either of the problems.Results: Isolated knee joint osteoarthritis is present in 183 subjects (22%), hyperuricemia was present in 154 subjects (18.55%). There is a significant positive association present between isolated knee joint osteoarthritis and the highest level of serum uric acid (adjusted odd’s ratio-2.24, 95% confidence interval-1.57-2.94). There is a significant positive association between high serum uric acid levels and progression of the knee joint osteoarthritis (highest level versus lowest level of serum uric acid odd’s ratio-1.38, 95% confidence interval-0.96-2.74).Conclusions: It is concluded that knee joint osteoarthritis and its progression are associated with hyperuricemia

Influence of an Engineered Notch on the Electromagnetic Radiation Performance of NiTi Shape Memory Alloy

This work explores the influence of a pre-engineered notch on the electromagnetic radiation (EMR) parameters in NiTi shape memory alloy (SMA) during tensile tests. The test data showed that the EMR signal fluctuated between oscillatory and exponential, signifying that the specimen’s viscosity damping coefficient changes during strain hardening. The EMR parameters, maximum EMR amplitude, and average EMR energy release rate remained constant initially but rose sharply with the plastic zone radius with progressive loading. It was postulated that new Frank–Read sources permit dislocation multiplication and increase the number of edge dislocations participating in EMR emissions, leading to a rise in the value of EMR parameters. The study of the correlation between EMR emission parameters and the plastic zone radius before the crack tip is a vital crack growth monitoring tool. An analysis of the interrelationship of the EMR energy release rate at fracture with the elastic strain energy release rate would help develop an innovative approach to assess fracture toughness, a critical parameter for the design and safety of metals. The microstructural analysis of tensile fractures and the interrelation between deformation behaviours concerning the EMR parameters offers a novel and real-time approach to improve the extant understanding of the behaviour of metallic materials