Contactless electrical conductivity measurement of metallic submicron-grain material: Application to the study of aluminum with severe plastic deformation

We measured the electrical conductivity σ of aluminum specimen consisting of submicron-grains by observing the AC magnetic susceptibility resulting from the eddy current. By using a commercial platform for magnetic measurement, contactless measurement of the relative electrical conductivity σn of a nonmagnetic metal is possible over a wide temperature (T) range. By referring to σ at room temperature, obtained by the four-terminal method, σn(T) was transformed into σ(T). This approach is useful for cylinder specimens, in which the estimation of the radius and/or volume is difficult. An experiment in which aluminum underwent accumulative roll bonding, which is a severe plastic deformation process, validated this method of evaluating σ as a function of the fraction of high-angle grain boundaries

Kenali, Cegah dan Atasi Dislipidemia Recognize, Prevent, and Eradicate Dyslipidemia

Dislipidemia adalah kelainan metabolisme lipid yang ditandai dengan peningkatan maupun penurunan satu atau lebih fraksi lipid dalam darah. Peningkatan kadar kolesterol total dan LDL darah dapat disebabkan oleh peningkatan konsumsi lemak jenuh dan kolesterol yang tinggi dalam makanan. Pada perjalanan dislipidemia, apabila kadar kolesterol tidak terkontrol dengan baik, maka akan meningkatkan risiko terjadi nya komplikasi baik akut maupun kronis. Pada umumnya, sebagian masyarakat telah mengenal perihal kolesterol secara umum namun mungkin belum memahami bagaimana cara mencegah dan mengatasi kadar kolesterol darah yang tinggi. Edukasi yang baik disertai terapi nutrisi, jasmani dan tatalaksana farmakologi diharapkan dapat mengendalikan progresifitas penyakit dislipidemia dan komplikasinya. Oleh karena itu pengabdian masyarakat berbasis webinar ini diadakan selain untuk meningkatkan keilmuan, juga diharapkan dapat meningkatkan kesadaran akan bahaya dari penyakit dislipidemia. Kegiatan webinar ini menargetkan mahasiswa UTA45 dan masyarakat umum dengan luaran yang diharapkan yaitu dapat meningkatkan pengetahuan tentang penyakit dislipidemia. Webinar dengan metode presentasi dan tanya jawab yang dilaksanakan pada 27 April 2022. Total peserta yang mengikuti kegiatan webinar dengan mengisi absen secara online sebanyak 66 peserta. Persentase rata – rata total skor prestest perserta sebesar 70,2% dan rata – rata skor posttest sebesar 79,6% dapat dilihat bahwa terjadi peningkatan skor posttest sebesar 9,4%

Combination of p53AIP1 and survivin expression is a powerful prognostic marker in non-small cell lung cancer

<p>Abstract</p> <p>Background</p> <p>p53AIP1 is a potential mediator of apoptosis depending on p53, which is mutated in many kinds of carcinoma. High survivin expression in non-small cell lung cancer is related with poor prognosis. To investigate the role of these genes in non-small cell lung cancer, we compared the relationship between p53AIP1 or survivin gene expression and the clinicopathological status of lung cancer.</p> <p>Materials and methods</p> <p>Forty-seven samples from non-small cell lung cancer patients were obtained between 1997 and 2003. For quantitative evaluation of RNA expression by PCR, we used Taqman PCR methods.</p> <p>Results</p> <p>Although no correlation between p53AIP1 or survivin gene expression and clinicopathological factors was found, the relationship between survivin gene expression and nodal status was significant (p = 0.03). Overall survival in the p53AIP1-negative group was significantly worse than in the positive group (p = 0.04); however, although survivin expression was not a prognostic factor, the combination of p53AIP1 and survivin was a significant prognostic predictor (p = 0.04). In the multivariate cox proportional hazard model, the combination was an independent predictor of overall survival (p53AIP1 (+) survivin (+), HR 0.21, 95%CI = [0.01–1.66]; p53AIP1 (+) survivin (-), HR 0.01, 95%CI = [0.002–0.28]; p53AIP1 (-) survivin (-), HR 0.01, 95%CI = [0.002–3.1], against p53AIP1 (-) survivin (+), p = 0.03).</p> <p>Conclusion</p> <p>These data suggest that the combination of p53AIP1 and survivin gene expression may be a powerful tool to stratify subgroups with better or worse prognosis from the variable non-small cell lung cancer population.</p

Traveling EEG slow oscillation along the dorsal attention network initiates spontaneous perceptual switching

An ambiguous figure such as the Necker cube causes spontaneous perceptual switching (SPS). The mechanism of SPS in multistable perception has not yet been determined. Although early psychological studies suggested that SPS may be caused by fatigue or satiation of orientation, the neural mechanism of SPS is still unknown. Functional magnetic resonance imaging (fMRI) has shown that the dorsal attention network (DAN), which mainly controls voluntary attention, is involved in bistable perception of the Necker cube. To determine whether neural dynamics along the DAN cause SPS, we performed simultaneous electroencephalography (EEG) and fMRI during an SPS task with the Necker cube, with every SPS reported by pressing a button. This EEG–fMRI integrated analysis showed that (a) 3–4 Hz spectral EEG power modulation at fronto-central, parietal, and centro-parietal electrode sites sequentially appeared from 750 to 350 ms prior to the button press; and (b) activations correlating with the EEG modulation traveled along the DAN from the frontal to the parietal regions. These findings suggest that slow oscillation initiates SPS through global dynamics along the attentional system such as the DAN