Chemical Composition, an Antioxidant, Cytotoxic and Microbiological Activity of the Essential Oil from the Leaves of <i>Aeollanthus suaveolens</i> Mart. ex Spreng

<div><p><i>Aeollanthus suaveolens</i> species popularly known as catinga de mulata belongs to the Lamiaceae family. In the Amazon region, it is used in folk medicine for the treatment of gastritis, convulsions of epileptic origin, stomach pain and diarrhea in the form of tea and juice. Essential oils have analgesic, anti-inflammatory, and antimicrobial activity. This study evaluated the chemical composition of the <i>A</i>. <i>suaveolens</i> essential oil, and its cytotoxic, antimicrobial and antioxidant activity on <i>Artemia salina</i> Leach. The plant species was collected in Fazendinha district in the city of Macapa-AP. The essential oil obtained from the process was performed by hydrodistillation and identification of components by gas chromatography coupled with mass spectrometer. The antioxidant activity was evaluated by the kidnapping method of 2,2- diphenyl -1-picrilhidrazil radical, while the cytotoxic activity was assessed using saline A. and the microbiological activity was carried out by microdilution method with <i>Escherichia coli</i>, <i>Salmonella</i> sp. and <i>Staphylococcus aureus</i> bacteria. In a chromatographic analysis, the major constituents found in the essential oil of <i>A</i>. <i>suaveolens</i> were (E) -β-farnesene (37.615%), Linalool (33.375%), α-Santalene (3.255%) and linalyl acetate (3.222%). The results showed that the <i>Escherichia coli</i> and <i>Salmonella</i> sp. bacteria were more susceptible to MIC 50 mg.mL^-1 when compared with the <i>Staphylococcus aureus</i> bacterium MIC 100 mg.mL^-1. With respect to MBC concentration of 100 mg.mL^-1 it was sufficient to inhibit the growth of <i>E</i>. <i>coli</i>. The essential oil did not show antioxidant activity, however, has a high cytotoxic activity against the <i>A</i>. <i>salina</i>, LC₅₀ 8.90 μg.mL^-1.</p></div

Essential oil toxicity of <i>Aeollanthus suaveolens</i> front of the larvae of <i>A</i>. <i>salina</i>.

<p>Essential oil toxicity of <i>Aeollanthus suaveolens</i> front of the larvae of <i>A</i>. <i>salina</i>.</p

Antioxidant activity of <i>Aeollanthus suaveolens</i> essential oil.

<p>Antioxidant activity of <i>Aeollanthus suaveolens</i> essential oil.</p

Chemical composition of the <i>Aeollanthus suaveolens</i> essential oil.

<p>Chemical composition of the <i>Aeollanthus suaveolens</i> essential oil.</p