15 research outputs found
Low Doses of Bisphenol A and Diethylstilbestrol Impair Ca Signals in Pancreatic Ī±-Cells through a Nonclassical Membrane Estrogen Receptor within Intact Islets of Langerhans-9
<p><b>Copyright information:</b></p><p>Taken from "Low Doses of Bisphenol A and Diethylstilbestrol Impair Ca Signals in Pancreatic Ī±-Cells through a Nonclassical Membrane Estrogen Receptor within Intact Islets of Langerhans"</p><p>Environmental Health Perspectives 2005;113(8):969-977.</p><p>Published online 18 May 2005</p><p>PMCID:PMC1280335.</p><p>This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original DOI.</p
Low Doses of Bisphenol A and Diethylstilbestrol Impair Ca Signals in Pancreatic Ī±-Cells through a Nonclassical Membrane Estrogen Receptor within Intact Islets of Langerhans-8
<p><b>Copyright information:</b></p><p>Taken from "Low Doses of Bisphenol A and Diethylstilbestrol Impair Ca Signals in Pancreatic Ī±-Cells through a Nonclassical Membrane Estrogen Receptor within Intact Islets of Langerhans"</p><p>Environmental Health Perspectives 2005;113(8):969-977.</p><p>Published online 18 May 2005</p><p>PMCID:PMC1280335.</p><p>This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original DOI.</p
Hypothetical model of the molecular pathway involved in E-induced Ca regulation in Ī±-cells
<p><b>Copyright information:</b></p><p>Taken from "Low Doses of Bisphenol A and Diethylstilbestrol Impair Ca Signals in Pancreatic Ī±-Cells through a Nonclassical Membrane Estrogen Receptor within Intact Islets of Langerhans"</p><p>Environmental Health Perspectives 2005;113(8):969-977.</p><p>Published online 18 May 2005</p><p>PMCID:PMC1280335.</p><p>This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original DOI.</p> Abbreviations: G, G-protein; P, intra-cellular phosphate. 17Ī²-E and EDCs activate a PTX-sensitive pathway, indicating either that a G-proteinācoupled receptor (GPCR) is involved or that a receptor with a different structure from GPCRs is coupled to a classical GPCR that activates a G-protein. This receptor is coupled in a yet undetermined manner with NOS, which generates NO. This activates soluble GC, which increases cGMP levels, which activates PKG, regulating ion channels and producing the abolishment of low-glucoseāinduced [Ca]
Low Doses of Bisphenol A and Diethylstilbestrol Impair Ca Signals in Pancreatic Ī±-Cells through a Nonclassical Membrane Estrogen Receptor within Intact Islets of Langerhans-5
<p><b>Copyright information:</b></p><p>Taken from "Low Doses of Bisphenol A and Diethylstilbestrol Impair Ca Signals in Pancreatic Ī±-Cells through a Nonclassical Membrane Estrogen Receptor within Intact Islets of Langerhans"</p><p>Environmental Health Perspectives 2005;113(8):969-977.</p><p>Published online 18 May 2005</p><p>PMCID:PMC1280335.</p><p>This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original DOI.</p
Low Doses of Bisphenol A and Diethylstilbestrol Impair Ca Signals in Pancreatic Ī±-Cells through a Nonclassical Membrane Estrogen Receptor within Intact Islets of Langerhans-7
<p><b>Copyright information:</b></p><p>Taken from "Low Doses of Bisphenol A and Diethylstilbestrol Impair Ca Signals in Pancreatic Ī±-Cells through a Nonclassical Membrane Estrogen Receptor within Intact Islets of Langerhans"</p><p>Environmental Health Perspectives 2005;113(8):969-977.</p><p>Published online 18 May 2005</p><p>PMCID:PMC1280335.</p><p>This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original DOI.</p
Low Doses of Bisphenol A and Diethylstilbestrol Impair Ca Signals in Pancreatic Ī±-Cells through a Nonclassical Membrane Estrogen Receptor within Intact Islets of Langerhans-3
<p><b>Copyright information:</b></p><p>Taken from "Low Doses of Bisphenol A and Diethylstilbestrol Impair Ca Signals in Pancreatic Ī±-Cells through a Nonclassical Membrane Estrogen Receptor within Intact Islets of Langerhans"</p><p>Environmental Health Perspectives 2005;113(8):969-977.</p><p>Published online 18 May 2005</p><p>PMCID:PMC1280335.</p><p>This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original DOI.</p
Low Doses of Bisphenol A and Diethylstilbestrol Impair Ca Signals in Pancreatic Ī±-Cells through a Nonclassical Membrane Estrogen Receptor within Intact Islets of Langerhans-1
<p><b>Copyright information:</b></p><p>Taken from "Low Doses of Bisphenol A and Diethylstilbestrol Impair Ca Signals in Pancreatic Ī±-Cells through a Nonclassical Membrane Estrogen Receptor within Intact Islets of Langerhans"</p><p>Environmental Health Perspectives 2005;113(8):969-977.</p><p>Published online 18 May 2005</p><p>PMCID:PMC1280335.</p><p>This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original DOI.</p
Low Doses of Bisphenol A and Diethylstilbestrol Impair Ca Signals in Pancreatic Ī±-Cells through a Nonclassical Membrane Estrogen Receptor within Intact Islets of Langerhans-6
<p><b>Copyright information:</b></p><p>Taken from "Low Doses of Bisphenol A and Diethylstilbestrol Impair Ca Signals in Pancreatic Ī±-Cells through a Nonclassical Membrane Estrogen Receptor within Intact Islets of Langerhans"</p><p>Environmental Health Perspectives 2005;113(8):969-977.</p><p>Published online 18 May 2005</p><p>PMCID:PMC1280335.</p><p>This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original DOI.</p
STX does not change glucose homeostasis in ovariectomized female mice.
<p>A, Intraperitoneal glucose tolerance test (IPGTT) in ovariectomized female mice after one single dose of vehicle (ā¢) or 100 Āµg/kg STX (ā). B, Area under the curve in the IPGTT in A; nā=ā7ā8 mice/condition. C, Body weight in ovariectomized female mice before and after the 6 day-treatment with either vehicle or STX; nā=ā5ā6 mice/condition. D, Fasting glycemia in the following morning after the 6-day treatment with vehicle or STX treated mice (nā=ā5ā6 mice/condition). E, IPGTT in the same mice as in D; vehicle (ā¢), STX (ā); nā=ā5ā6 mice/condition. F, Insulin content in isolated islets from vehicle and STX-treated ovariectomized female mice; nā=ā110ā140 islets from 4ā6 mice/condition.</p
STX does not alter insulin content or blood glucose homeostasis at long-term in male mice.
<p>A, Body weight in male mice before and after the 6 day-treatment with either vehicle or STX; nā=ā5 mice/condition. B, Fasting glycemia in the following morning after the 6-day treatment with vehicle or STX treated mice (nā=ā5 mice/condition). C, IPGTT in the same mice as in B; vehicle (ā¢), STX (ā); nā=ā4ā5 mice/condition. D, Insulin content in isolated islets from vehicle and STX-treated mice; nā=ā60ā120 islets from 2ā3 mice/condition.</p