Obesity Is Associated with Changes in Iron Nutrition Status and Its Homeostatic Regulation in Pregnancy

The influence of obesity on maternal iron homeostasis and nutrition status during pregnancy remains only partially clarified. Our study objectives were (1) to describe how obesity influences broad iron nutrition spectrum biomarkers such as available or circulating iron (serum transferrin receptor (sTfr) and serum iron), iron reserves (ferritin), and functional iron (hemoglobin); and (2) to depict the regulating role of hepcidin. The above was carried out while considering influential factors such as initial iron nutrition status, iron intake, and the presence of inflammation. Ninety three non-anemic pregnant adult women were included, 40 with obesity (Ob) and 53 with adequate weight (AW); all took ≈30 mg/day of supplementary iron. Information on iron intake and blood samples were obtained at gestational weeks 13, 20, 27, and 35. A series of repeated measure analyses were performed using General Linear Models to discern the effect of obesity on each iron indicator; iron intake, hepcidin, and C-reactive protein were successively introduced as covariates. Available and circulating iron was lower in obese women: sTfr was higher (p = 0.07) and serum iron was lower (p = 0.01); and ferritin and hemoglobin were not different between groups. Hepcidin was higher in the Ob group (p = 0.01) and was a significant predictor variable for all biomarkers. Obesity during pregnancy dysregulates iron homeostasis, resembling “obesity hypoferremia„

Tendencias en la circulación, experiencias y resignificaciones de la migración y el retorno en el Estado de Méxíco

Para abonar al estudio de las migraciones entre México y Estados Unidos y en especial de las migraciones y los migrantes desde el Estrado de México, el libro Continuidades y Cambios en las Migraciones de México a Estados Unidos. Tendencia en la circulación, experiencia y significaciones de la migración y el retorno en el ]Estado de México compila un total de 16 Capítulos que con diferentes acercamientos posicionamientos teóricos y metodologías basadas en estudios de caso y análisis cuantitativo y cualitativo exponen diversas temáticas que revisten la complejidad que ha adquirido el fenómeno migratorio. También exponen la migración internacional desde el Estado de México, entidad que además de constituirse como un Territorio expulsor de migrantes internacionales, ha incrementado su importancia como receptor de migrantes de retorno(no necesariamente originarios del Estado de México) y migrantes en transito que buscan llegar al vecino país del norte