Idiopathic gingival fibromatosis with unilateral aggressive periodontitis: A case report

BACKGROUND AND AIM: Until now there are a few case reports in which idiopathic gingival enlargement and aggressive periodontitis are diagnosed in combination but in none of them unilateral aggressive periodontitis was seen. CASE REPORT: A 25-year-old female was referred with the chief complaint of swelling of the gingiva in the regions of right upper and lower jaws, for the past 7 years. No relevant medical or family history was recorded. There was not any local or environmental factor. On physical examination, generalized diffused enlargement of gingiva was observed. Radiographs showed unilateral advanced destruction of supporting bone in right upper and lower sextants. The histological analysis of excisional biopsy revealed hyper parakeratinized epithelium. Enormous distribution of inflammatory cells was seen in subepithelial tissue. RESULTS: The combination of gingival fibromatosis (GF) and unilateral aggressive periodontitis in this rare case can be a kind of syndromic form that is uncommon in GF. There is little information in this area. KEYWORDS: Gingival Fibromatosis, Agressive Periodontitis, Unilateral Bone Loss, Gingival Enlargemen

Different type of periodontitis and gingivitis in patients with major thalassemia comparing to healthy people

BACKGROUND AND AIM: Iran is located on the thalassemia belt and has the highest prevalence rate of patients compared to the general population in the world. This investigation was performed to determine the prevalence of gingivitis and periodontitis in thalassemia patients in comparison to healthy people and evaluate the relationship between periodontal disease and age, gender, splenectomy and dosage of desferal. METHODS: In this cross-sectional study, 133 thalassemia patients and 133 healthy people were examined. Clinical examination was performed by periodontal probe and age, gender, desferal dosage, smoking, occlusion, dental alignment were recorded. The results were analyzed using ANOVA, Chi-square, and t-test. RESULTS: Prevalence of gingivitis and periodontitis in thalassemia patients was significantly higher than the control group (P = 0.049). However, no difference was observed in the severity of periodontitis. Results showed that age, xerostomia and splenectomy are associated with periodontitis, and dental alignment was correlated with gingivitis. Calculus index (CI) was reported to be more in thalassemia patients, but results showed no significant difference in debris index (DI) however DI was significantly higher in anterior maxillary sextant. CONCLUSION: Due to the higher prevalence of gingivitis and periodontitis in patients with thalassemia and susceptibility to infection, preventive and therapeutic treatment is essential in these patients. KEYWORDS: Major Thalassemia, Gingivitis, Periodontitis, Splenectomy, Desfera

Disseminated Strongyloidiasis in an Immunodeficient Patient (Pemphigus Vulgaris) Due to Corticosteroid Therapy: A Case Report

Strongyloidiasis is a frequent misdiagnosed parasitic infection in the world that caused by Strongyloides stercoralis. In Iran, the disease is predominantly reported from warm and humid climate provinces. The patient was a 54-yr-old man, originated from Khuzestan Province with a history of pemphigus and diabetes that was treated with high-dose of corticosteroid drugs before admission in a non-private hospital in Shiraz, Iran in 2014. After different primary diagnosis and administrating of several drugs, endoscopy and histopatholgical biopsy revealed a massive S. stercoralis infection in the duodenal mucosa and gastric wall. In spite treating with anti-helminthic drugs in the last days, due to using different steroid drugs, clinical manifestations of the patient were exacerbated and he was expired on the seventeenth day due to severe dyspnea. Physicians’ awareness and using various diagnosis methods like serology, endoscopy, and biopsy should be considered in the endemic areas. In suspicious cases, anthelmintic drugs should be started before the initiation of immunosuppressive therapy